GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons.
Pelsman et al. 2003·International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience·cited by 45
PMID 12711349DOI 10.1016/s0736-5748(03)00031-5PUB-12711349
Full text at the publisher9 results where Noopept (omberacetam) was given
Ex vivo tissue · mouse · 2006
Taurine rescues hippocampal long-term potentiation from ammonia-induced impairment.
Chepkova et al. 2006·Neurobiology of disease·cited by 44
PMID 16766203DOI 10.1016/j.nbd.2006.04.006PUB-16766203
Full text at the publisher1 result where Noopept (omberacetam) was given
Animal study (in vivo) · mouse · 2007
The nootropic and neuroprotective proline-containing dipeptide noopept restores spatial memory and increases immunoreactivity to amyloid in an Alzheimer's disease model.
Ostrovskaya et al. 2007·Journal of psychopharmacology (Oxford, England)·cited by 33
PMID 17092975DOI 10.1177/0269881106071335PUB-17092975
Full text at the publisher5 results where Noopept (omberacetam) was given
Animal study (in vivo) · rat · 2021
Noopept Attenuates Diabetes-Mediated Neuropathic Pain and Oxidative Hippocampal Neurotoxicity via Inhibition of TRPV1 Channel in Rats.
Düzova et al. 2021·Molecular neurobiology·cited by 28
PMID 34241806DOI 10.1007/s12035-021-02478-8PUB-34241806
Full text at the publisher19 results where Noopept (omberacetam) was given
Animal study (in vivo) · rat · 1999
Memory restoring and neuroprotective effects of the proline-containing dipeptide, GVS-111, in a photochemical stroke model.
Ostrovskaya et al. 1999·Behavioural pharmacology·cited by 23
PMID 10780261DOI 10.1097/00008877-199909000-00013PUB-10780261
Full text at the publisher2 results where Noopept (omberacetam) was given
Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation.
Ostrovskaya et al. 2014·Journal of biomedical science·cited by 17
PMID 25096780PMC4422191DOI 10.1186/s12929-014-0074-2PUB-25096780
CC BY8 results where Noopept (omberacetam) was given
Animal study (in vivo) · rat · 1997
The major metabolite of dipeptide piracetam analogue GVS-111 in rat brain and its similarity to endogenous neuropeptide cyclo-L-prolylglycine.
Gudasheva et al. 1997·European journal of drug metabolism and pharmacokinetics·cited by 13
PMID 9358206DOI 10.1007/bf03189814PUB-09358206
Full text at the publisher2 results where Noopept (omberacetam) was given (plus 2 on tools or combinations, listed separately)
Animal study (in vivo) · rat · 2014
Noopept normalizes parameters of the incretin system in rats with experimental diabetes.
Ostrovskaya et al. 2014·Bulletin of experimental biology and medicine·cited by 13
PMID 25065315DOI 10.1007/s10517-014-2562-5PUB-25065315
Full text at the publisher4 results where Noopept (omberacetam) was given
In vitro (cells) · helix pomatia · 1997
The effects of piracetam and its novel peptide analogue GVS-111 on neuronal voltage-gated calcium and potassium channels.
Solntseva et al. 1997·General pharmacology·cited by 12
PMID 9195198DOI 10.1016/s0306-3623(96)00529-0PUB-09195198
Full text at the publisher5 results where Noopept (omberacetam) was given
Ex vivo tissue · helix pomatia · 2002
Selective suppression of the slow-inactivating potassium currents by nootropics in molluscan neurons.
Bukanova et al. 2002·The international journal of neuropsychopharmacology·cited by 12
PMID 12366875DOI 10.1017/s1461145702002997PUB-12366875
Rights unknown4 results where Noopept (omberacetam) was given
Animal study (in vivo) · rat · 2008
Noopept stimulates the expression of NGF and BDNF in rat hippocampus.
Ostrovskaya et al. 2008·Bulletin of experimental biology and medicine·cited by 12
PMID 19240853DOI 10.1007/s10517-008-0297-xPUB-19240853
Full text at the publisher7 results where Noopept (omberacetam) was given
Neuroprotective and nootropic drug noopept rescues α-synuclein amyloid cytotoxicity.
Jia et al. 2011·Journal of molecular biology·cited by 11
PMID 21986202DOI 10.1016/j.jmb.2011.09.044PUB-21986202
Full text at the publisher3 results where Noopept (omberacetam) was given
Neuroprotective properties of nootropic dipeptide GVS-111 in in vitro oxygen-glucose deprivation, glutamate toxicity and oxidative stress.
Andreeva et al. 2000·Bulletin of experimental biology and medicine·cited by 10
PMID 11177296DOI 10.1023/a:1002828707337PUB-11177296
Full text at the publisher4 results where Noopept (omberacetam) was given
Animal study (in vivo) · rat · 2008
Noopept efficiency in experimental Alzheimer disease (cognitive deficiency caused by beta-amyloid25-35 injection into Meynert basal nuclei of rats).
Ostrovskaya et al. 2008·Bulletin of experimental biology and medicine·cited by 9
PMID 19145356DOI 10.1007/s10517-008-0211-6PUB-19145356
Full text at the publisher2 results where Noopept (omberacetam) was given
Not a test of Noopept (omberacetam) alone · 2021
QbD-driven development of dissolving microneedle patch loaded with ultradeformable liposomes encapsulated Noopept: Exploring a patient friendly, once-daily option to manage dementia.
Srivastava et al. 2021·European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·cited by 9
PMID 34126240DOI 10.1016/j.ejps.2021.105909PUB-34126240
Full text at the publisher8 results where Noopept (omberacetam) was a tool, carrier or part of a combination
Animal study (in vivo) · rat · 2011
Effects of nootropics on the EEG in conscious rats and their modification by glutamatergic inhibitors.
Vorobyov et al. 2011·Brain research bulletin·cited by 7
PMID 21414388DOI 10.1016/j.brainresbull.2011.02.011PUB-21414388
Full text at the publisher3 results where Noopept (omberacetam) was given (plus 3 on tools or combinations, listed separately)
Animal study (in vivo) · rat · 2022
Intranasal Administration of Forskolin and Noopept Reverses Parkinsonian Pathology in PINK1 Knockout Rats.
Dagda et al. 2022·International journal of molecular sciences·cited by 7
PMID 36614135PMC9820624DOI 10.3390/ijms24010690PUB-36614135
CC BY1 result where Noopept (omberacetam) was given (plus 7 on tools or combinations, listed separately)
Animal study (in vivo) · rat · 1997
The novel substituted acylproline-containing dipeptide, GVS-111, promotes the restoration of learning and memory impaired by bilateral frontal lobectomy in rats.
Ostrovskaya et al. 1997·Behavioural pharmacology·cited by 6
PMID 9833021PUB-09833021
Full text at the publisher3 results where Noopept (omberacetam) was given
Cognitive Enhancer Noopept Activates Transcription Factor HIF-1.
Zainullina et al. 2020·Doklady. Biochemistry and biophysics·cited by 6
PMID 33119829DOI 10.1134/s1607672920050129PUB-33119829
Full text at the publisher5 results where Noopept (omberacetam) was given