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Study · Animal study (in vivo) · rat · 2005

9 results

[Comparative study of the long-term behavioral effects of noopept and piracetam in adult male rats and female rats in postnatal period].

Voronina TA, Guzevatykh LS, Trofimov SS

Eksperimental'naia i klinicheskaia farmakologiia1 Mar 2005Cited by 1 (Europe PMC)

PMID15934357 (opens in a new tab)PepBankPUB-15934357
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study9

8 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, noopept suppressed horizontal activity during the period from the 8th to 20th day versus saline controls.

    In plain wordsIn rats, noopept reduced horizontal activity compared with saline controls.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseHorizontal activity
    Study

    ratn: not reported in source

    Comparator
    0.9 % aqueous NaCl solution
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    0.1 mg/kg dailyAs given in this study (rat).

    Source sentences

    Summary
    In the period from 8th to 20th day, both drugs (cognitive enhancers) suppressed the horizontal and vertical activity and the anxiety in test animals as compared to the control group treated with 0.9 % aqueous NaCl solution.
    1 context sentence
    Summary · context
    Adult male and female rats were treated with the peptide nootrope drug noopept (daily dose, 0.1 mg/kg) and piracetam (200 mg/kg).
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, noopept suppressed vertical activity during the period from the 8th to 20th day versus saline controls.

    In plain wordsIn rats, noopept reduced vertical activity compared with saline controls.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseVertical activity
    Study

    ratn: not reported in source

    Comparator
    0.9 % aqueous NaCl solution
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    0.1 mg/kg dailyAs given in this study (rat).

    Source sentences

    Summary
    In the period from 8th to 20th day, both drugs (cognitive enhancers) suppressed the horizontal and vertical activity and the anxiety in test animals as compared to the control group treated with 0.9 % aqueous NaCl solution.
    1 context sentence
    Summary · context
    Adult male and female rats were treated with the peptide nootrope drug noopept (daily dose, 0.1 mg/kg) and piracetam (200 mg/kg).
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats, noopept suppressed anxiety during the period from the 8th to 20th day versus saline controls.

    In plain wordsIn rats, noopept reduced anxiety compared with saline controls.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseAnxiety
    Study

    ratn: not reported in source

    Comparator
    0.9 % aqueous NaCl solution
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    0.1 mg/kg dailyAs given in this study (rat).

    Source sentences

    Summary
    In the period from 8th to 20th day, both drugs (cognitive enhancers) suppressed the horizontal and vertical activity and the anxiety in test animals as compared to the control group treated with 0.9 % aqueous NaCl solution.
    1 context sentence
    Summary · context
    Adult male and female rats were treated with the peptide nootrope drug noopept (daily dose, 0.1 mg/kg) and piracetam (200 mg/kg).
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In female rats, early postnatal noopept injections did not affect morphological development.

    In plain wordsIn female rats, early noopept injections did not affect body development.

    Peptide
    Noopept (omberacetam)
    Outcome
    No significant changeMorphological development
    Study

    ratn: not reported in source

    Adult female rats after early postnatal injections
    Outcome group
    Cell proliferation and differentiation · Nervous system and cognition
    Studied dose
    0.1 mg/kg dailyAs given in this study (rat).

    Source sentences

    Summary
    Early postnatal injections of the nootropes influenced neither the morphology development nor the behavior of adult female rats in the plus maze, extrapolational escape, passive avoidance, and pain sensitivity threshold tests.
    1 context sentence
    Summary · context
    Adult male and female rats were treated with the peptide nootrope drug noopept (daily dose, 0.1 mg/kg) and piracetam (200 mg/kg).
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In adult female rats, early postnatal noopept injections did not affect plus maze behavior.

    In plain wordsIn adult female rats, early noopept injections did not affect plus maze behavior.

    Peptide
    Noopept (omberacetam)
    Outcome
    No significant changePlus maze behavior
    Study

    ratn: not reported in source

    Adult female rats after early postnatal injections
    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    0.1 mg/kg dailyAs given in this study (rat).

    Source sentences

    Summary
    Early postnatal injections of the nootropes influenced neither the morphology development nor the behavior of adult female rats in the plus maze, extrapolational escape, passive avoidance, and pain sensitivity threshold tests.
    1 context sentence
    Summary · context
    Adult male and female rats were treated with the peptide nootrope drug noopept (daily dose, 0.1 mg/kg) and piracetam (200 mg/kg).
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In adult female rats, early postnatal noopept injections did not affect extrapolational escape behavior.

    In plain wordsIn adult female rats, early noopept injections did not affect escape task behavior.

    Peptide
    Noopept (omberacetam)
    Outcome
    No significant changeExtrapolational escape behavior
    Study

    ratn: not reported in source

    Adult female rats after early postnatal injections
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.1 mg/kg dailyAs given in this study (rat).

    Source sentences

    Summary
    Early postnatal injections of the nootropes influenced neither the morphology development nor the behavior of adult female rats in the plus maze, extrapolational escape, passive avoidance, and pain sensitivity threshold tests.
    1 context sentence
    Summary · context
    Adult male and female rats were treated with the peptide nootrope drug noopept (daily dose, 0.1 mg/kg) and piracetam (200 mg/kg).
  7. 07AnimalAnimal study (in vivo)Efficacy outcome

    In adult female rats, early postnatal noopept injections did not affect passive avoidance behavior.

    In plain wordsIn adult female rats, early noopept injections did not affect passive avoidance behavior.

    Peptide
    Noopept (omberacetam)
    Outcome
    No significant changePassive avoidance behavior
    Study

    ratn: not reported in source

    Adult female rats after early postnatal injections
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.1 mg/kg dailyAs given in this study (rat).

    Source sentences

    Summary
    Early postnatal injections of the nootropes influenced neither the morphology development nor the behavior of adult female rats in the plus maze, extrapolational escape, passive avoidance, and pain sensitivity threshold tests.
    1 context sentence
    Summary · context
    Adult male and female rats were treated with the peptide nootrope drug noopept (daily dose, 0.1 mg/kg) and piracetam (200 mg/kg).
  8. 08AnimalAnimal study (in vivo)Efficacy outcome

    In adult female rats, early postnatal noopept injections did not affect pain sensitivity thresholds.

    In plain wordsIn adult female rats, early noopept injections did not affect pain thresholds.

    Peptide
    Noopept (omberacetam)
    Outcome
    No significant changePain sensitivity threshold
    Study

    ratn: not reported in source

    Adult female rats after early postnatal injections
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    0.1 mg/kg dailyAs given in this study (rat).

    Source sentences

    Summary
    Early postnatal injections of the nootropes influenced neither the morphology development nor the behavior of adult female rats in the plus maze, extrapolational escape, passive avoidance, and pain sensitivity threshold tests.
    1 context sentence
    Summary · context
    Adult male and female rats were treated with the peptide nootrope drug noopept (daily dose, 0.1 mg/kg) and piracetam (200 mg/kg).

Studies that did not test the peptide alone1

In this study, Noopept (omberacetam) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Noopept (omberacetam).

  1. 09AnimalNot a test of Noopept (omberacetam) aloneAnimal study (in vivo)Efficacy outcome

    In rats, noopept-treated and saline control groups showed greater open field habituation than intact rats in a poor sensory environment.

    In plain wordsIn rats, noopept-treated and saline groups showed more habituation than intact rats with poor sensory stimulation.

    Peptide
    Noopept (omberacetam)
    Outcome
    IncreaseOpen field habituation
    Study

    ratn: not reported in source

    Comparator
    Intact rats in a poor sensory environment
    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    Animals in the "intact" group (having received neither drugs not physiological solution, that is, developing in a poor sensor environment), showed less pronounced habituation in the open field test as compared to the control and drug treated groups.
    1 context sentence
    Summary · context
    Adult male and female rats were treated with the peptide nootrope drug noopept (daily dose, 0.1 mg/kg) and piracetam (200 mg/kg).

    In this study, Noopept (omberacetam) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Noopept (omberacetam).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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