Skip to content

Study · Animal study (in vivo) · rat · 2008

2 results

Noopept efficiency in experimental Alzheimer disease (cognitive deficiency caused by beta-amyloid25-35 injection into Meynert basal nuclei of rats).

Ostrovskaya RU, Belnik AP, Storozheva ZI

Bulletin of experimental biology and medicine1 Jul 2008Cited by 9 (Europe PMC)

PMID19145356 (opens in a new tab)DOI10.1007/s10517-008-0211-6 (opens in a new tab)PepBankPUB-19145356
Publisher pagePubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with amyloid-induced cognitive deficiency, preventive Noopept completely prevented memory disorders.

    In plain wordsIn rats with amyloid-induced brain injury, preventive Noopept completely prevented memory disorders.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreasePrevention of memory disorders
    Study

    ratn: not reported in source

    Adult Wistar rats with beta-amyloid25-35 injection into Meynert basal nuclei
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.5 mg/kg · intraperitoneal · 7 days before injuryAs given in this study (rat).

    Source sentences

    Summary
    Preventive (for 7 days before the injury) intraperitoneal injections of noopept in a dose of 0.5 mg/kg completely prevented mnestic disorders under conditions of this model.
    1 context sentence
    Summary · context
    Experiments on adult Wistar rats showed that injection of beta-amyloid25-35 (2 microg) into Meynert basal nuclei caused long-term memory deficiency which was detected 24 days after this injection by the memory trace retrieval in conditioned passive avoidance reflex (CPAR).
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats with amyloid-induced cognitive deficiency, Noopept significantly normalized impairment when treatment started 15 days after injury.

    In plain wordsIn rats with amyloid-induced brain injury, Noopept reduced cognitive impairment when treatment started 15 days after injury.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseNormalization of cognitive deficiency after injury
    Study

    ratn: not reported in source

    Adult Wistar rats with beta-amyloid25-35 injection into Meynert basal nuclei
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Noopept exhibited a significant normalizing effect, if the treatment was started 15 days after the injury, when neurodegenerative changes in the basal nuclei, cortex, and hippocampus were still acutely pronounced.
    1 context sentence
    Summary · context
    Experiments on adult Wistar rats showed that injection of beta-amyloid25-35 (2 microg) into Meynert basal nuclei caused long-term memory deficiency which was detected 24 days after this injection by the memory trace retrieval in conditioned passive avoidance reflex (CPAR).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.