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Study · Animal study (in vivo) · rat · 2008

2 results

Original nootropic drug noopept prevents memory deficit in rats with muscarinic and nicotinic receptor blockade.

Radionova KS, Belnik AP, Ostrovskaya RU

Bulletin of experimental biology and medicine1 Jul 2008Cited by 2 (Europe PMC)

PMID19145351 (opens in a new tab)DOI10.1007/s10517-008-0209-0 (opens in a new tab)PepBankPUB-19145351
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with cholinoceptor blockade, Noopept abolished the antagonist effect described in the abstract as antiamnesic.

    In plain wordsIn rats with receptor blockade, Noopept abolished the antagonist effect that the abstract calls antiamnesic.

    Peptide
    Noopept (omberacetam)
    Outcome
    MixedAntagonist-associated memory effect
    Study

    ratn: not reported in source

    Muscarinic and nicotinic receptor blockade
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Noopept abolished the antiamnesic effect of cholinoceptor antagonists and improved spatial preference.
    2 context sentences
    Summary · context
    Antiamnesic activity of Noopept was studied on the original three-way model of conditioned passive avoidance response, which allows studying spatial component of memory.
    Summary · context
    Cholinoceptor antagonists of both types (scopolamine and mecamylamine) decreased entry latency and reduced the probability for selection of the safe compartment.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats with cholinoceptor blockade, Noopept improved spatial preference.

    In plain wordsIn rats with receptor blockade, Noopept improved spatial preference.

    Peptide
    Noopept (omberacetam)
    Outcome
    IncreaseSpatial preference
    Study

    ratn: not reported in source

    Muscarinic and nicotinic receptor blockade
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Noopept abolished the antiamnesic effect of cholinoceptor antagonists and improved spatial preference.
    2 context sentences
    Summary · context
    Antiamnesic activity of Noopept was studied on the original three-way model of conditioned passive avoidance response, which allows studying spatial component of memory.
    Summary · context
    Cholinoceptor antagonists of both types (scopolamine and mecamylamine) decreased entry latency and reduced the probability for selection of the safe compartment.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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