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Study · Animal study (in vivo) · rat · 2013

5 results

Efficiency of noopept in streptozotocin-induced diabetes in rats.

Ostrovskaya RU, Ozerova IV, Gudascheva TA, Kapitsa IG, Ivanova EA, Voronina TA, Seredenin SB

Bulletin of experimental biology and medicine1 Jan 2013Cited by 4 (Europe PMC)

PMID23484194 (opens in a new tab)DOI10.1007/s10517-013-1944-4 (opens in a new tab)PepBankPUB-23484194
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In diabetic rats, Noopept alleviated glycemia.

    In plain wordsIn rats with diabetes, Noopept reduced blood sugar.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseGlycemia
    Study

    ratsn: not reported in source

    Streptozotocin-induced diabetes
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In experimental diabetic rats, Noopept alleviated glycemia and weight loss and normalized enhanced pain sensitivity.
    1 context sentence
    Summary · context
    We studied the effects of new nootropic and neuroprotective drug Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) in various dosage regimens on the dynamics of glycemia, body weight, and pain sensitivity in rats receiving diabetogenic toxin streptozotocin.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In diabetic rats, Noopept alleviated weight loss.

    In plain wordsIn rats with diabetes, Noopept reduced weight loss.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseWeight loss
    Study

    ratsn: not reported in source

    Streptozotocin-induced diabetes
    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In experimental diabetic rats, Noopept alleviated glycemia and weight loss and normalized enhanced pain sensitivity.
    1 context sentence
    Summary · context
    We studied the effects of new nootropic and neuroprotective drug Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) in various dosage regimens on the dynamics of glycemia, body weight, and pain sensitivity in rats receiving diabetogenic toxin streptozotocin.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In diabetic rats, Noopept normalized enhanced pain sensitivity.

    In plain wordsIn rats with diabetes, Noopept restored increased pain sensitivity toward normal.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseEnhanced pain sensitivity
    Study

    ratsn: not reported in source

    Streptozotocin-induced diabetes
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In experimental diabetic rats, Noopept alleviated glycemia and weight loss and normalized enhanced pain sensitivity.
    1 context sentence
    Summary · context
    We studied the effects of new nootropic and neuroprotective drug Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) in various dosage regimens on the dynamics of glycemia, body weight, and pain sensitivity in rats receiving diabetogenic toxin streptozotocin.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In diabetic rats, Noopept's normalizing effect was greatest with preventive administration before the toxin.

    In plain wordsIn rats with diabetes, Noopept had its greatest normalizing effect when given before the toxin rather than other regimens.

    Peptide
    Noopept (omberacetam)
    Outcome
    IncreaseNormalizing effect by administration timing
    Study

    ratsn: not reported in source

    Streptozotocin-induced diabetes
    Comparator
    Other administration regimens
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The normalizing effect of Noopept was most pronounced when it was administered as a preventive agent prior to injection of the toxin.
    1 context sentence
    Summary · context
    We studied the effects of new nootropic and neuroprotective drug Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) in various dosage regimens on the dynamics of glycemia, body weight, and pain sensitivity in rats receiving diabetogenic toxin streptozotocin.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In streptozotocin-treated rats, preventive and therapeutic Noopept administration, including delayed injections, significantly weakened the toxin-induced metabolic effects.

    In plain wordsIn rats, preventive and therapeutic Noopept treatment, including delayed injections, reduced the metabolic effects of streptozotocin.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseMetabolic effects with preventive and therapeutic administration
    Study

    ratsn: not reported in source

    Streptozotocin-induced diabetes
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Both preventive and therapeutic administration of Noopept (delayed injections included) significantly weakened the examined metabolic effects of diabetogenic toxin.
    1 context sentence
    Summary · context
    We studied the effects of new nootropic and neuroprotective drug Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) in various dosage regimens on the dynamics of glycemia, body weight, and pain sensitivity in rats receiving diabetogenic toxin streptozotocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

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