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Study · Non-randomized trial · n = 30 · 2009

5 results

[Prevention of neuro- and cardiotoxic side effects of tuberculosis chemotherapy with noopept].

Mordyk AV, Lysov AV, Kondria AV, Gol'dzon MA, Khlebova NV

Klinicheskaia meditsina1 Jan 2009

PMID19565831 (opens in a new tab)PepBankPUB-19565831
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. 5 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In patients with newly diagnosed respiratory tuberculosis, adjunctive Noopept promoted normalization of autonomic nervous system function.

    In plain wordsIn patients with tuberculosis, Noopept added to treatment promoted normal autonomic nervous system function.

    Peptide
    Noopept (omberacetam)
    Outcome
    Direction not reportedAutonomic nervous system function
    Study

    n = 30

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    10 mg twice daily · first monthAs given in this study (human).

    Source sentences

    Summary
    The treatment promoted functional normalization of vegetative nervous system and antioxidative systems, reduced manifestations of anxiety, decreased frequency of adverse neuro- and cardiotoxic responses to antituberculous drugs.
    2 context sentences
    Summary · context
    It included 60 patients with newly diagnosed respiratory tuberculosis.
    Summary · context
    Those in group 1 (n = 30) received 10 mg of noopept twice daily during the first month.
  2. 02HumanNon-randomized trialEfficacy outcome

    In patients with newly diagnosed respiratory tuberculosis, adjunctive Noopept promoted normalization of antioxidative systems.

    In plain wordsIn patients with tuberculosis, Noopept added to treatment promoted normal antioxidant function.

    Peptide
    Noopept (omberacetam)
    Outcome
    Direction not reportedAntioxidative systems
    Study

    n = 30

    Outcome group
    Oxidative stress · Whole body
    Studied dose
    10 mg twice daily · first monthAs given in this study (human).

    Source sentences

    Summary
    The treatment promoted functional normalization of vegetative nervous system and antioxidative systems, reduced manifestations of anxiety, decreased frequency of adverse neuro- and cardiotoxic responses to antituberculous drugs.
    2 context sentences
    Summary · context
    It included 60 patients with newly diagnosed respiratory tuberculosis.
    Summary · context
    Those in group 1 (n = 30) received 10 mg of noopept twice daily during the first month.
  3. 03HumanNon-randomized trialEfficacy outcome

    In patients with newly diagnosed respiratory tuberculosis, adjunctive Noopept reduced anxiety manifestations.

    In plain wordsIn patients with tuberculosis, Noopept added to treatment reduced anxiety symptoms.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseAnxiety manifestations
    Study

    n = 30

    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    10 mg twice daily · first monthAs given in this study (human).

    Source sentences

    Summary
    The treatment promoted functional normalization of vegetative nervous system and antioxidative systems, reduced manifestations of anxiety, decreased frequency of adverse neuro- and cardiotoxic responses to antituberculous drugs.
    2 context sentences
    Summary · context
    It included 60 patients with newly diagnosed respiratory tuberculosis.
    Summary · context
    Those in group 1 (n = 30) received 10 mg of noopept twice daily during the first month.
  4. 04HumanNon-randomized trialSafety outcome

    In patients with newly diagnosed respiratory tuberculosis, adjunctive Noopept decreased the frequency of neurotoxic responses to antituberculous drugs.

    In plain wordsIn patients with tuberculosis, Noopept added to treatment reduced neurotoxic reactions to tuberculosis drugs.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseNeurotoxic responses to antituberculous drugs
    Study

    n = 30

    Outcome group
    Adverse events · Nervous system and cognition
    Studied dose
    10 mg twice daily · first monthAs given in this study (human).

    Source sentences

    Summary
    The treatment promoted functional normalization of vegetative nervous system and antioxidative systems, reduced manifestations of anxiety, decreased frequency of adverse neuro- and cardiotoxic responses to antituberculous drugs.
    2 context sentences
    Summary · context
    It included 60 patients with newly diagnosed respiratory tuberculosis.
    Summary · context
    Those in group 1 (n = 30) received 10 mg of noopept twice daily during the first month.
  5. 05HumanNon-randomized trialSafety outcome

    In patients with newly diagnosed respiratory tuberculosis, adjunctive Noopept decreased the frequency of cardiotoxic responses to antituberculous drugs.

    In plain wordsIn patients with tuberculosis, Noopept added to treatment reduced cardiotoxic reactions to tuberculosis drugs.

    Peptide
    Noopept (omberacetam)
    Outcome
    DecreaseCardiotoxic responses to antituberculous drugs
    Study

    n = 30

    Outcome group
    Adverse events · Cardiovascular
    Studied dose
    10 mg twice daily · first monthAs given in this study (human).

    Source sentences

    Summary
    The treatment promoted functional normalization of vegetative nervous system and antioxidative systems, reduced manifestations of anxiety, decreased frequency of adverse neuro- and cardiotoxic responses to antituberculous drugs.
    2 context sentences
    Summary · context
    It included 60 patients with newly diagnosed respiratory tuberculosis.
    Summary · context
    Those in group 1 (n = 30) received 10 mg of noopept twice daily during the first month.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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