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Study · Non-randomized trial · 2007

4 results

[Meteoadaptogenic properties of peptide drugs in healthy volunteers].

Shabanov PD, Ganapol'skiĭ VP, Aleksandrov PV

Eksperimental'naia i klinicheskaia farmakologiia1 Nov 2007

PMID18318195 (opens in a new tab)PepBankPUB-18318195
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In healthy volunteers, noopept positively affected psychological functional state in cold and hot climates.

    In plain wordsIn healthy volunteers, noopept improved psychological functional state in cold and hot climates.

    Peptide
    Noopept (omberacetam)
    Outcome
    IncreasePsychological functional state in cold and hot climates
    Study

    n: not reported in source

    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Noopept, affecting positively a psychological component of the functional state, can be used for rapid adaptation to both cold and hot climate.
    1 context sentence
    Summary · context
    The meteoadaptogenic properties of a series of drugs with peptide (cortexin, noopept, dilept) and nonpeptide (vinpotropil) structure were investigated in a climate thermobarocomplex (Tabay, Japan) on a group of healthy volunteers aged 20-24.
  2. 02HumanNon-randomized trialEfficacy outcome

    In healthy volunteers, noopept enhanced physical work capacity in a hot climate.

    In plain wordsIn healthy volunteers, noopept increased physical work capacity in a hot climate.

    Peptide
    Noopept (omberacetam)
    Outcome
    IncreasePhysical work capacity in hot climate
    Study

    n: not reported in source

    Outcome group
    Exercise and physical function · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In the hot climate, noopept also enhanced the physical work capacity.
    1 context sentence
    Summary · context
    The meteoadaptogenic properties of a series of drugs with peptide (cortexin, noopept, dilept) and nonpeptide (vinpotropil) structure were investigated in a climate thermobarocomplex (Tabay, Japan) on a group of healthy volunteers aged 20-24.
  3. 03HumanNon-randomized trialEfficacy outcome

    In healthy volunteers, Cortexin qualified as an adaptogen and actoprotector only under hypobaric hypoxia.

    In plain wordsIn healthy volunteers, Cortexin showed adaptation and performance protection only under low-pressure, low-oxygen conditions.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    IncreaseAdaptogenic and actoprotective activity under hypobaric hypoxia
    Study

    n: not reported in source

    Outcome group
    Overall treatment effect · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cortexin is qualified as an adaptogen and actoprotector only for hypobaric hypoxia conditions (uplands).
    1 context sentence
    Summary · context
    The meteoadaptogenic properties of a series of drugs with peptide (cortexin, noopept, dilept) and nonpeptide (vinpotropil) structure were investigated in a climate thermobarocomplex (Tabay, Japan) on a group of healthy volunteers aged 20-24.

Studies that did not test the peptide alone1

In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cortexin (cortical polypeptide complex).

  1. 04HumanNot a test of Cortexin (cortical polypeptide complex) aloneNon-randomized trialEfficacy outcome

    In healthy volunteers, the studied drugs showed environment-dependent meteoadaptogenic action, without a separate Cortexin estimate.

    In plain wordsIn healthy volunteers, the studied drugs aided adaptation to environmental conditions. The abstract gives no separate Cortexin estimate.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    IncreaseMeteoadaptogenic action
    Study

    n: not reported in source

    Outcome group
    Overall treatment effect · Whole body

    Source sentences

    Summary
    All the studied drugs produced a meteoadaptogenic action, the extent of which depended on the environmental test conditions (overcooling, overheating, hypobaric hypoxia).
    1 context sentence
    Summary · context
    The meteoadaptogenic properties of a series of drugs with peptide (cortexin, noopept, dilept) and nonpeptide (vinpotropil) structure were investigated in a climate thermobarocomplex (Tabay, Japan) on a group of healthy volunteers aged 20-24.

    In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortexin (cortical polypeptide complex).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 18:59 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    21 Oct 2026, 15:58 UTC

    Study results updated

  3. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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