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Melanotan I (afamelanotide) studies: 218 papers with results

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  1. Quantitative analysis of MC1R gene expression in human skin cell cultures.

    Roberts DW · Pigment cell research · 2006

    In vitro (cells) · 2 results

  2. Activation of MAP kinase by MC4-R through PI3 kinase.

    Vongs A · Regulatory peptides · 2004

    In vitro (cells) · 4 results

  3. Cloning and expression of a new member of the melanocyte-stimulating hormone receptor family.

    Barrett P · Journal of molecular endocrinology · 1994

    In vitro (cells) · ovine receptor · 2 results

  4. Cultured human melanocytes respond to MSH peptides and ACTH.

    Hunt G · Pigment cell research · 1994

    In vitro (cells) · 6 results

  5. The human melanocyte stimulating hormone receptor has evolved to become "super-sensitive" to melanocortin peptides.

    Mountjoy KG · Molecular and cellular endocrinology · 1994

    In vitro (cells) · mouse · 2 results

  6. Melanocortin 4 receptor activation induces brain-derived neurotrophic factor expression in rat astrocytes through cyclic AMP-protein kinase A pathway.

    Caruso C · Molecular and cellular endocrinology · 2012

    In vitro (cells) · rat · 6 results

  7. Activation of the melanocortin-4 receptor mobilizes intracellular free calcium in immortalized hypothalamic neurons.

    Newman EA · The Journal of surgical research · 2006

    In vitro (cells) · 6 results

  8. Autoradiographic discrimination of melanocortin receptors indicates that the MC3 subtype dominates in the medial rat brain.

    Lindblom J · Brain research · 1998

    In vitro (cells) · 4 results

  9. Morphology and function of lacrimal gland acinar cells in primary culture.

    Hann LE · Investigative ophthalmology & visual science · 1989

    In vitro (cells) · rat · 2 results

  10. Peripheral effect of alpha-melanocyte-stimulating hormone on fatty acid oxidation in skeletal muscle.

    An JJ · The Journal of biological chemistry · 2007

    In vitro (cells) · 1 result

  11. Expression of functional melanocortin-4 receptor in the hypothalamic GT1-1 cell line.

    Khong K · Neuroendocrinology · 2001

    In vitro (cells) · 2 results

  12. Agouti signaling protein and other factors modulating differentiation and proliferation of immortal melanoblasts.

    Sviderskaya EV · Developmental dynamics : an official publication of the American Association of Anatomists · 2001

    In vitro (cells) · mouse · 3 results

  13. Evidence for alternate points of attachment for alpha-MSH and its stereoisomer [Nle4, D-Phe7]-alpha-MSH at the melanocortin-1 receptor.

    Frändberg PA · Biochemical and biophysical research communications · 1994

    In vitro (cells) · 1 result

  14. Melanocortin-3 receptor activates MAP kinase via PI3 kinase.

    Chai B · Regulatory peptides · 2007

    In vitro (cells) · 11 results

  15. Biased signaling initiated by agouti-related peptide through human melanocortin-3 and -4 receptors.

    Yang Z · Biochimica et biophysica acta · 2016

    In vitro (cells) · 3 results

  16. Differential regulation of cAMP-mediated gene transcription and ligand selectivity by MC3R and MC4R melanocortin receptors.

    Lee EJ · European journal of biochemistry · 2001

    In vitro (cells) · 1 result

  17. Proopiomelanocortin peptides and sebogenesis.

    Zhang L · Annals of the New York Academy of Sciences · 2003

    In vitro (cells) · 4 results

  18. Molecular cloning, tissue distribution, and pharmacological characterization of melanocortin-4 receptor in spotted scat, Scatophagus argus.

    Li JT · General and comparative endocrinology · 2016

    In vitro (cells) · spotted scat (receptor) · 3 results

  19. Melanocortin 4 receptor activates ERK-cFos pathway to increase brain-derived neurotrophic factor expression in rat astrocytes and hypothalamus.

    Ramírez D · Molecular and cellular endocrinology · 2015

    In vitro (cells) · rat · 7 results

  20. MC1R variant allele effects on UVR-induced phosphorylation of p38, p53, and DDB2 repair protein responses in melanocytic cells in culture.

    Wong SS · The Journal of investigative dermatology · 2012

    In vitro (cells) · 7 results

  21. Agouti-related protein antagonizes glucocorticoid production induced through melanocortin 4 receptor activation in bovine adrenal cells: a possible autocrine control.

    Doghman M · Endocrinology · 2004

    In vitro (cells) · bovine · 3 results

  22. Melanocortin-4 receptor in swamp eel (Monopterus albus): Cloning, tissue distribution, and pharmacology.

    Yi TL · Gene · 2018

    In vitro (cells) · 2 results

  23. Molecular cloning and pharmacological characterization of porcine melanocortin-3 receptor.

    Fan ZC · The Journal of endocrinology · 2008

    In vitro (cells) · 5 results

  24. Alpha-melanocyte-stimulating hormone and endothelin-1 have opposing effects on melanocyte adhesion, migration, and pp125FAK phosphorylation.

    Scott G · Experimental cell research · 1997

    In vitro (cells) · 3 results

  25. Molecular cloning, tissue distribution, and pharmacological characterization of melanocortin-4 receptor in grass carp (Ctenopharyngodon idella).

    Li L · Domestic animal endocrinology · 2017

    In vitro (cells) · grass carp (receptor) · 3 results

  26. [Nle4, D-Phe7]-α-MSH Inhibits Toll-Like Receptor (TLR)2- and TLR4-Induced Microglial Activation and Promotes a M2-Like Phenotype.

    Carniglia L · PloS one · 2016

    In vitro (cells) · rat · 8 results

  27. Kinetic evidence for tandemly arranged ligand binding sites in melanocortin 4 receptor complexes.

    Kopanchuk S · Neurochemistry international · 2006

    In vitro (cells) · 4 results

  28. Binding and internalization of the melanocyte stimulating hormone receptor ligand [Nle4, D-Phe7] alpha-MSH in B16 melanoma cells.

    Wong W · The international journal of biochemistry & cell biology · 1996

    In vitro (cells) · mouse · 9 results

  29. Leptin infusion and obesity in mouse cause alterations in the hypothalamic melanocortin system.

    Gout J · Obesity (Silver Spring, Md.) · 2008

    In vitro (cells) · mouse · 1 result

  30. Melanocytes expressing MC1R polymorphisms associated with red hair color have altered MSH-ligand activated pigmentary responses in coculture with keratinocytes.

    Roberts DW · Journal of cellular physiology · 2008

    In vitro (cells) · 2 results

  31. Analyzing the signaling properties of gar (Lepisosteus oculatus) melanocortin receptors: Evaluating interactions with MRAP1 and MRAP2.

    Wolverton EA · General and comparative endocrinology · 2019

    In vitro (cells) · chinese hamster · 5 results

  32. Analysis of the pharmacological properties of chicken melanocortin-2 receptor (cMC2R) and chicken melanocortin-2 accessory protein 1 (cMRAP1).

    Barlock TK · General and comparative endocrinology · 2014

    In vitro (cells) · chicken receptor · 1 result

  33. Three novel human sporadic melanoma cell lines: signaling pathways controlled by MC1R, BRAF and β-catenins.

    Zanna P · Journal of biological regulators and homeostatic agents · 2013

    In vitro (cells) · 1 result

  34. NDP-MSH reduces oxidative damage induced by palmitic acid in primary astrocytes.

    Ramírez D · Journal of neuroendocrinology · 2019

    In vitro (cells) · 7 results

  35. Functional characterization of melanocortin-3 receptor in rainbow trout (Oncorhynchus mykiss).

    Yu HX · Fish physiology and biochemistry · 2022

    In vitro (cells) · rainbow trout · 4 results

  36. Melanocortin 4 receptor activation protects striatal neurons and glial cells from 3-nitropropionic acid toxicity.

    Saba J · Molecular and cellular neurosciences · 2019

    In vitro (cells) · rat · 7 results

  37. Functional Characterization of Melanocortin-3 Receptor in a Hibernating Cavefish Onychostoma macrolepis.

    Wu L · Animals : an open access journal from MDPI · 2021

    In vitro (cells) · onychostoma macrolepis · 3 results

  38. The melanocortin 4 receptor: oligomer formation, interaction sites and functional significance.

    Chapman KL · Biochimica et biophysica acta · 2013

    In vitro (cells) · 2 results

  39. Characterization of cell lines stably expressing human normal or mutated EGFP-tagged MC4R.

    Blondet A · Journal of biochemistry · 2004

    In vitro (cells) · 2 results

  40. Molecular cloning, tissue distribution, and pharmacological characterization of blunt snout bream (Megalobrama amblycephala) melanocortin-5 receptor.

    Liao S · Fish physiology and biochemistry · 2019

    In vitro (cells) · 1 result

  41. Melanocortin-4 receptor activation promotes insulin-stimulated mTOR signaling.

    Chai B · Peptides · 2010

    In vitro (cells) · 4 results

  42. The melanocortin receptor agonist NDP-MSH impairs the allostimulatory function of dendritic cells.

    Rennalls LP · Immunology · 2010

    In vitro (cells) · 7 results

  43. Mitogen- and stress-activated protein kinase-1 activation is involved in melanocortin-induced BDNF expression in Neuro2a neuronal cells.

    Zhang W · Neuroreport · 2020

    In vitro (cells) · mouse · 7 results

  44. Pharmacology of the giant panda (Ailuropoda melanoleuca) melanocortin-3 receptor.

    Zhang HJ · General and comparative endocrinology · 2019

    In vitro (cells) · 2 results

  45. Stable expression of human melanocortin 3 receptor fused to EGFP in the HEK293 cells.

    Rached M · Biochemical and biophysical research communications · 2003

    In vitro (cells) · 1 result

  46. Molecular cloning and pharmacological characterization of giant panda (Ailuropoda melanoleuca) melanocortin-4 receptor.

    Wang ZQ · General and comparative endocrinology · 2016

    In vitro (cells) · giant panda (receptor) · 2 results

  47. Melanogenic response of the Kupffer cells of Rana esculenta L to melanocyte stimulating hormone.

    Guida G · Pigment cell research · 2004

    In vitro (cells) · rana esculenta · 3 results

  48. Molecular cloning and functional characterization of melanocortin-3 receptor in grass carp (Ctenopharyngodon idella).

    Mo H · Fish physiology and biochemistry · 2023

    In vitro (cells) · grass carp · 2 results

  49. Molecular cloning, tissue distribution, and pharmacologic function of melanocortin-3 receptor in common carp (Cyprinus carpio).

    Du YY · General and comparative endocrinology · 2023

    In vitro (cells) · common carp · 3 results

  50. Pharmacological characterization of three chicken melanocortin-3 receptor mutants.

    Zhang HJ · Domestic animal endocrinology · 2021

    In vitro (cells) · chicken · 4 results

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