IGF-1 DES (des(1-3)IGF-I) studies: 150 papers with results
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- Insulin-like growth factor (IGF)-I regulates IGF-binding protein-5 gene expression through the phosphatidylinositol 3-kinase, protein kinase B/Akt, and p70 S6 kinase signaling pathway.
Duan C · The Journal of biological chemistry · 1999
In vitro (cells) · 7 results
- Regulation of vascular smooth muscle cell responses to insulin-like growth factor (IGF)-I by local IGF-binding proteins.
Hsieh T · The Journal of biological chemistry · 2003
In vitro (cells) · 2 results
- Protein kinases C-gamma and -delta are involved in insulin-like growth factor I-induced migration of colonic epithelial cells.
André F · Gastroenterology · 1999
In vitro (cells) · 1 result
- Insulin-like growth factor (IGF)-II binding to IGF-binding proteins and IGF receptors is modified by deletion of the N-terminal hexapeptide or substitution of arginine for glutamate-6 in IGF-II.
Francis GL · The Biochemical journal · 1993
In vitro (cells) · rat · 3 results
- A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.
Bagley CJ · The Biochemical journal · 1989
In vitro (cells) · rat · 3 results
- Mitogenic effect of the insulin analogue glargine in malignant cells in comparison with insulin and IGF-I.
Liefvendahl E · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2008
In vitro (cells) · 1 result
- Insulin-like growth factors stimulate expression of hepatocyte growth factor but not transforming growth factor beta1 in cultured hepatic stellate cells.
Skrtic S · Endocrinology · 1997
In vitro (cells) · rat · 4 results
- Human renal fibroblasts modulate proximal tubule cell growth and transport via the IGF-I axis.
Johnson DW · Kidney international · 1997
In vitro (cells) · 1 result
- Membrane-associated insulin-like growth factor-binding protein-3 inhibits insulin-like growth factor-I-induced insulin-like growth factor-I receptor signaling in ishikawa endometrial cancer cells.
Karas M · The Journal of biological chemistry · 1997
In vitro (cells) · 3 results
- Interactions between growth hormone, insulin-like growth factor I, and basic fibroblast growth factor in melanocyte growth.
Edmondson SR · The Journal of clinical endocrinology and metabolism · 1999
In vitro (cells) · 4 results
- IGF-I stimulates chemotaxis of human neuroblasts. Involvement of type 1 IGF receptor, IGF binding proteins, phosphatidylinositol-3 kinase pathway and plasmin system.
Puglianiello A · The Journal of endocrinology · 2000
In vitro (cells) · 3 results
- Insulin and insulin-like growth factors (IGFs) stimulate production of IGF-binding proteins by ovarian granulosa cells.
Grimes RW · Endocrinology · 1992
In vitro (cells) · 6 results
- Combination of insulin-like growth factor (IGF)-I and IGF-binding protein-1 promotes fibroblast-embedded collagen gel contraction.
Lee YR · Endocrinology · 1996
In vitro (cells) · 2 results
- des-(1-3)-IGF-I, an insulin-like growth factor analog used to mimic a potential IGF-II autocrine loop, promotes the differentiation of human colon-carcinoma cells.
Remacle-Bonnet M · International journal of cancer · 1992
In vitro (cells) · 5 results
- Skeletal muscle cell-derived insulin-like growth factor (IGF) binding proteins inhibit IGF-I-induced myogenesis in rat L6E9 cells.
Silverman LA · Endocrinology · 1995
In vitro (cells) · rat · 4 results
- Regulation of insulin-like growth factor-binding protein-5 by insulin-like growth factor I and interleukin-1alpha in ovine articular chondrocytes.
Sunic D · Endocrinology · 1998
In vitro (cells) · sheep · 8 results
- Retrovirally mediated overexpression of insulin-like growth factor binding protein 4: evidence that insulin-like growth factor is required for skeletal muscle differentiation.
Damon SE · Journal of cellular physiology · 1998
In vitro (cells) · mouse · 1 result
- Differential effects of IGF-binding proteins, IGFBP-3 and IGFBP-5, on IGF-I action and binding to cell membranes of immortalized human chondrocytes.
Matsumoto T · The Journal of endocrinology · 2000
In vitro (cells) · 2 results
- Inhibition of cellular proliferation and modulation of insulin-like growth factor binding proteins by retinoids in a bovine mammary epithelial cell line.
Woodward TL · Journal of cellular physiology · 1996
In vitro (cells) · bovine · 5 results
- Expression of insulin-like growth factor binding protein-3 (IGFBP-3) in human keratinocytes is regulated by EGF and TGFbeta1.
Edmondson SR · Journal of cellular physiology · 1999
In vitro (cells) · 2 results
- IGF-binding protein-6 is involved in growth inhibition in SH-SY5Y human neuroblastoma cells: its production is both IGF- and cell density-dependent.
Babajko S · The Journal of endocrinology · 1997
In vitro (cells) · 8 results
- Granulosa cell-derived insulin-like growth factor (IGF) binding proteins are inhibitory to IGF-I hormonal action. Evidence derived from the use of a truncated IGF-I analogue.
Adashi EY · The Journal of clinical investigation · 1992
In vitro (cells) · rat · 2 results
- Protective role of retinoic acid from antiproliferative action of TNF-alpha on lung epithelial cells.
Besnard V · American journal of physiology. Lung cellular and molecular physiology · 2002
In vitro (cells) · 1 result
- Regulation of insulin-like growth factor-binding protein-4 in human endometrial stromal cell cultures: evidence for ligand-induced proteolysis.
Irwin JC · The Journal of clinical endocrinology and metabolism · 1995
In vitro (cells) · 3 results
- Insulinlike growth factor-binding protein modulates the growth response to insulinlike growth factor 1 by human gastric cancer cells.
Guo YS · Gastroenterology · 1993
In vitro (cells) · 1 result
- Evidence for insulin-like growth factor (IGF)-independent transcriptional regulation of IGF binding protein-3 by growth hormone in SKHEP-1 human hepatocarcinoma cells.
Gucev ZS · Endocrinology · 1997
In vitro (cells) · 2 results
- The role of the acid-labile subunit in regulating insulin-like growth factor transport across human umbilical vein endothelial cell monolayers.
Payet LD · The Journal of clinical endocrinology and metabolism · 2004
In vitro (cells) · 1 result
- Effect of insulin-like growth factor (IGF)-I and Des (1-3) IGF-I on the level of IGF binding protein-3 and IGF binding protein-3 mRNA in cultured porcine embryonic muscle cells.
Yang F · Journal of cellular physiology · 1999
In vitro (cells) · pig · 2 results
- Transcriptional and post-translational regulation of insulin-like growth factor-binding protein-5 in rat articular chondrocytes.
Matsumoto T · The Journal of endocrinology · 1996
In vitro (cells) · rat · 4 results
- Insulin-like growth factor (IGF) suppression of IGFBP-1 production: evidence for mediation by the type I IGF receptor.
Lee PD · Regulatory peptides · 1993
In vitro (cells) · 4 results
- Influence of IGF-IR stimulation or blockade on proliferation of human renal cell carcinoma cell lines.
Rosendahl A · International journal of oncology · 2004
In vitro (cells) · 1 result
- Inhibition of insulin-like growth factor I activity contributes to the premature apoptosis of cerebellar granule neuron in weaver mutant mice: in vitro analysis.
Zhong J · Journal of neuroscience research · 2002
In vitro (cells) · mouse · 3 results
- Insulin-like growth factor binding proteins (IGF-BPs) in bovine articular and ovine growth-plate chondrocyte cultures: their regulation by IGFs and modulation of proteoglycan synthesis.
Sunic D · Biochimica et biophysica acta · 1995
In vitro (cells) · bovine and ovine · 6 results
- Expression and down-regulation by retinoic acid of IGF binding protein-2 and -4 in medium from human neuroblastoma cells.
Bernardini S · Journal of neuroendocrinology · 1994
In vitro (cells) · 3 results
- Involvement of insulin-like growth factor-1 and its binding proteins in proliferation and differentiation of murine bone marrow-derived macrophage precursors.
Long E · Endocrine · 1998
In vitro (cells) · mouse · 6 results
- Epidermal growth factor-induced activation of the insulin-like growth factor I receptor in rat hepatocytes.
Hallak H · Hepatology (Baltimore, Md.) · 2002
In vitro (cells) · rat · 1 result
- Interrelationships between follicle stimulating hormone and the growth hormone--insulin-like growth factor--IGF-binding proteins axes in human granulosa cells in culture.
Barreca A · Journal of endocrinological investigation · 1996
In vitro (cells) · 2 results
- Des (1-3) IGF-I-stimulated growth of human stromal BPH cells is inhibited by a vitamin D3 analogue.
Crescioli C · Molecular and cellular endocrinology · 2002
In vitro (cells) · 3 results
- Insulin-like growth factor binding protein production in bovine retinal endothelial cells.
Giannini S · Metabolism: clinical and experimental · 1997
In vitro (cells) · bovine · 2 results
- Differential regulation by TGF-beta 1 and insulin of insulin-like growth factor binding protein-2 in IEC-6 cells.
Guo YS · The American journal of physiology · 1995
In vitro (cells) · 2 results
- Hormonal and extracellular matrix regulation of plasminogen activator in a bovine mammary epithelial cell line.
Politis I · Endocrine · 1995
In vitro (cells) · bovine · 2 results
- Insulin-like growth factors enhance phagocytosis by human neutrophils in vitro.
Jin GF · Regulatory peptides · 1993
In vitro (cells) · 8 results
- Insulin-like growth factor (IGF)-I stimulates IGF-I and type 1 IGF receptor expression in cultured rat granulosa cells: autocrine regulation of the intrafollicular IGF-I system.
deMoura MD · Endocrine · 2000
In vitro (cells) · rat · 2 results
- Insulin-like growth factors I and II induce cell death in Wilms's tumour cells.
Granérus M · Molecular pathology : MP · 2001
In vitro (cells) · 5 results
- The effects of insulin-like growth factor-I (IGF-I), IGF-II and des(1-3)IGF-I, a potent IGF analogue, on growth hormone and IGF-binding protein secretion from cultured rat anterior pituitary cells.
Simes JM · The Journal of endocrinology · 1991
In vitro (cells) · rat · 4 results
- Do insulin-like growth factor binding proteins (IGFBPs) modulate the IGF-I growth promoting and differentiating effects in human neuroblastoma cells?
Cianfarani S · European journal of endocrinology · 1996
In vitro (cells) · 3 results
- Expression and synthesis of insulin-like growth factor (IGF)-I, -II and their receptors in human glioma cell lines.
Zumkeller W · International journal of oncology · 1996
In vitro (cells) · 1 result
- Effect of the somatostatin analog, octreotide, and of other hormones on the release of the acid-labile subunit of the 150 kDa complex by rat hepatocyte in primary culture.
Barreca AM · European journal of endocrinology · 1997
In vitro (cells) · rat · 1 result
- Effects of insulin-like growth factor-I and its analogues on bovine hydrogen peroxide release by neutrophils and blastogenesis by mononuclear cells.
Zhao X · The Journal of endocrinology · 1993
In vitro (cells) · bovine · 8 results
- [Expression of mechano-growth factor in Escherichia coli and activity analysis].
Zhang B · Sheng wu gong cheng xue bao = Chinese journal of biotechnology · 2008
In vitro (cells) · 5 results