IGF-1 DES (des(1-3)IGF-I) studies: 150 papers with results
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- Platelet-activating factor enhances production of insulin-like growth factor binding proteins in a human adenocarcinoma cell line (HEC-1A)
Giannini S · Gynecologic oncology · 1996
In vitro (cells) · 3 results
- The processing of insulin-like growth factor-I (IGF-I) by a cultured kidney cell line is altered by IGF-binding protein-3.
Fawcett J · Endocrinology · 1995
In vitro (cells) · opossum · 2 results
- Response of the porcine MYH4-promoter and MYH4-expressing myotubes to known anabolic and catabolic agents in vitro.
Brearley MC · Biochemistry and biophysics reports · 2021
In vitro (cells) · mouse · 2 results
- Insulin-like growth factor binding protein-1 from Hep G2 cells is potently inhibited by the truncated IGF-I analogue des-(1-3) IGF-I.
Lindgren BF · Acta endocrinologica · 1993
In vitro (cells) · 8 results
- Characterization of the IGF axis in a rat liver-derived epithelial cell line.
Bramani S · Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 1999
In vitro (cells) · rat · 2 results
- Gene construction, expression, and characterization of double-copy truncated form of human insulin-like growth factor I.
Sun HY · Acta pharmacologica Sinica · 2001
In vitro (cells) · 4 results
- Gene construction, expression, and characterization of double-copy truncated form of human insulin-like growth factor Ⅰ
Sun Heying · Zhongguo yao li xue bao = Acta pharmacologica Sinica · 2001
In vitro (cells) · 4 results
- Binding of insulin-like growth factor (IGF) I or II to IGF-binding protein-2 enables it to bind to heparin and extracellular matrix.
Arai T · Endocrinology · 1996
In vitro (cell-free) · 1 result
- Two insulin-like growth factor (IGF)-binding proteins are responsible for the selective affinity for IGF-II of cerebrospinal fluid binding proteins.
Roghani M · The Journal of clinical endocrinology and metabolism · 1991
In vitro (cell-free) · 2 results
- Classification of the insulin-like growth factor binding proteins into three distinct categories according to their binding specificities.
Forbes B · Biochemical and biophysical research communications · 1988
In vitro (cell-free) · 2 results
- BIAcore analysis of bovine insulin-like growth factor (IGF)-binding protein-2 identifies major IGF binding site determinants in both the amino- and carboxyl-terminal domains.
Carrick FE · The Journal of biological chemistry · 2001
In vitro (cell-free) · 3 results
- Characterization of an insulin-like growth factor binding protein-5 protease produced by rat articular chondrocytes and a neuroblastoma cell line.
Matsumoto T · Growth regulation · 1996
In vitro (cell-free) · rat · 1 result
- PDGF-BB regulates IGF-mediated IGFBP-4 proteolysis in fetal lung fibroblasts.
Price WA · Experimental lung research · 2001
In vitro (cell-free) · rat · 1 result
- Cooperative interaction between mutant p53 and des(1-3)IGF-I accelerates mammary tumorigenesis.
Hadsell DL · Oncogene · 2000
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 10 results
- Enforced epithelial expression of IGF-1 causes hyperplastic prostate growth while negative selection is requisite for spontaneous metastogenesis.
Kaplan-Lefko PJ · Oncogene · 2008
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 9 results
- Overexpression of des(1-3) insulin-like growth factor 1 in the mammary glands of transgenic mice delays the loss of milk production with prolonged lactation.
Hadsell DL · Biology of reproduction · 2005
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 9 results
- Insulin-like growth factor-I (IGF-I) and especially IGF-I variants are anabolic in dexamethasone-treated rats.
Tomas FM · The Biochemical journal · 1992
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 14 results
- Insulin-like growth factor (IGF) binding protein-3 inhibits type 1 IGF receptor activation independently of its IGF binding affinity.
Ricort JM · Endocrinology · 2001
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 5 results
- Differential effects of retinoids on proliferation of bovine mammary epithelial cells in collagen gel culture.
Purup S · The Journal of dairy research · 2001
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 5 results
- Differences in the association of insulin-like growth factor-I (IGF-I) and IGF-I variants with rat, sheep, pig, human and chicken plasma-binding proteins.
Lord AP · The Journal of endocrinology · 1994
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 8 results
- Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-independent activation of beta-catenin signaling.
Sunters A · The Journal of biological chemistry · 2010
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 3 results
- Antiproliferative effects of insulin-like growth factor-binding protein-3 in mesenchymal chondrogenic cell line RCJ3.1C5.18. relationship to differentiation stage.
Spagnoli A · The Journal of biological chemistry · 2001
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 3 results
- Insulin-like growth factor-binding protein-3 activates a phosphotyrosine phosphatase. Effects on the insulin-like growth factor signaling pathway.
Ricort JM · The Journal of biological chemistry · 2002
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 3 results
- Efficient transdermal delivery of functional protein cargoes by a hydrophobic peptide MTD 1067.
Shin HJ · Scientific reports · 2022
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 6 results
- Expression, purification and characterization of secreted recombinant human insulin-like growth factor-I (IGF-I) and the potent variant des(1-3) IGF-I in Chinese hamster ovary cells.
McKinnon P · Journal of molecular endocrinology · 1991
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 6 results
- Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease.
Loeser RF · Arthritis and rheumatism · 2000
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 2 results
- Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1.
Ross M · The Biochemical journal · 1989
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 2 results
- Characterization of the affinities of insulin-like growth factor (IGF)-binding proteins 1-4 for IGF-I, IGF-II, IGF-I/insulin hybrid, and IGF-I analogs.
Oh Y · Endocrinology · 1993
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 2 results
- Insulin-like growth factor-I and its N-terminal modified analogues induce marked gut growth in dexamethasone-treated rats.
Read LC · The Journal of endocrinology · 1992
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 3 results
- Interaction between the insulin-like growth factor family and the integrin receptor family in tissue repair processes. Evidence in a rabbit ear dermal ulcer model.
Galiano RD · The Journal of clinical investigation · 1996
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 2 results
- Insulin-like growth factor (IGF)-binding protein-related protein-1: an autocrine/paracrine factor that inhibits skeletal myoblast differentiation but permits proliferation in response to IGF.
Haugk KL · Endocrinology · 2000
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 2 results
- A 30-kDa fragment of insulin-like growth factor (IGF) binding protein-3 in human pregnancy serum with strongly reduced IGF-I binding.
Ahlsén M · Cellular and molecular life sciences : CMLS · 2007
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 2 results
- Effect of IGFBP-3 on IGF- and IGF-analogue-induced insulin-like growth factor-I receptor (IGFIR) signalling.
Devi GR · Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2001
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 2 results
- Insulin-like growth factor-I and- II in combination inhibit the release of growth hormone-releasing hormone from the rat hypothalamus in vitro.
Korbonits M · Growth regulation · 1996
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 2 results
- Insulin-like growth factor binding protein 2 is a growth inhibitory protein conserved in zebrafish.
Duan C · Proceedings of the National Academy of Sciences of the United States of America · 1999
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Osteogenic protein-1 and insulin-like growth factor I synergistically stimulate rat osteoblastic cell differentiation and proliferation.
Yeh LC · Endocrinology · 1997
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Overexpression of an inhibitory insulin-like growth factor binding protein (IGFBP), IGFBP-4, delays onset of prostate tumor formation.
Damon SE · Endocrinology · 1998
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts.
Min Y · Gut · 2005
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer's V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner.
Niikura T · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Impaired glucose homeostasis in insulin-like growth factor binding protein-1 transgenic mice.
Rajkumar K · The Journal of clinical investigation · 1996
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Insulin-like growth factor-II as a paracrine growth factor in human neuroblastoma cells.
Leventhal PS · Experimental cell research · 1995
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Expression of insulin-like growth factor-binding protein 6 complementary DNA alters neuroblastoma cell growth.
Grellier P · Cancer research · 1998
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Biosensor measurement of the binding of insulin-like growth factors I and II and their analogues to the insulin-like growth factor-binding protein-3.
Heding A · The Journal of biological chemistry · 1996
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Regulation of proliferation of prostate epithelial cells by 1,25-dihydroxyvitamin D3 is accompanied by an increase in insulin-like growth factor binding protein-3.
Sprenger CC · The Journal of endocrinology · 2001
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Inhibition of insulin-like growth factor I receptor signaling by the vitamin D analogue EB1089 in MCF-7 breast cancer cells: A role for insulin-like growth factor binding proteins.
Rozen F · International journal of oncology · 1999
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Fibroblast growth factor-2 over-rides insulin-like growth factor-I induced proliferation and cell survival in human neuroblastoma cells.
Russo VC · Journal of cellular physiology · 2004
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Insulin-like growth factor binding protein-1 induces insulin release in the rat.
Mortensen DL · Endocrinology · 1997
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- IGFBPs modulate IGF-I- and high glucose-controlled growth of human retinal endothelial cells.
Giannini S · The Journal of endocrinology · 2001
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result
- Modulation of insulin-like growth factor (IGF) action by IGF-binding proteins in normal, benign, and malignant smooth muscle tissues.
van der Ven LT · The Journal of clinical endocrinology and metabolism · 1996
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 3 results
- Overexpression of insulin-like growth factor binding protein 4 (IGFBP-4) in MCF-7 breast cancer cells is associated with reduced responsiveness to insulin-like growth factors in vitro and reduced tumour growth in vivo.
Huynh H · International journal of oncology · 1997
Not a test of IGF-1 DES (des(1-3)IGF-I) alone · 1 result