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Study · In vitro (cells) · 1993

1 result

Insulinlike growth factor-binding protein modulates the growth response to insulinlike growth factor 1 by human gastric cancer cells.

Guo YS, Beauchamp RD, Jin GF, Townsend CM Jr, Thompson JC

Gastroenterology1 Jun 1993Cited by 24 (Europe PMC)

PMID7684715 (opens in a new tab)DOI10.1016/0016-5085(93)90634-o (opens in a new tab)PepBankPUB-07684715
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In AGS gastric cancer cells, des (1-3) IGF-1 stimulated growth in a dose-dependent manner.

    In plain wordsIn cells, des (1-3) IGF-1 increased gastric cancer cell growth with increasing dose.

    Peptide
    IGF-1 DES (des(1-3)IGF-I)
    Outcome
    IncreaseCell growth
    Study

    humann: not reported in source

    AGS gastric cancer cells
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    des (1-3) IGF-1, a truncated IGF-1 with very low affinity to IGFBPs, stimulated AGS cell growth in dose-dependent fashion.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 13:52 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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