Skip to content

Study · In vitro (cells) · 2004

1 result

Influence of IGF-IR stimulation or blockade on proliferation of human renal cell carcinoma cell lines.

Rosendahl A, Forsberg G

International journal of oncology1 Nov 2004Cited by 17 (Europe PMC)

PMID15492822 (opens in a new tab)DOI10.3892/ijo.25.5.1327 (opens in a new tab)PepBankPUB-15492822
Publisher pagePubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In renal carcinoma cells, Caki-2 proliferated more vigorously than SK-RC-52 in response to des(1‑3)IGF-I.

    In plain wordsIn cells, des(1‑3)IGF-I stimulated more proliferation in Caki-2 than SK-RC-52 renal cancer cells.

    Peptide
    IGF-1 DES (des(1-3)IGF-I)
    Outcome
    IncreaseCell proliferation
    Study

    humann: not reported in source

    Caki-2 and SK-RC-52 renal carcinoma cells
    Comparator
    SK-RC-52 cells
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Caki-2 expressed higher levels of IGF-IR and proliferated more vigorously to added IGF-I, IGF-I analogues des(1-3)IGF-I, LongR3IGF-I and IGF-II compared to SK-RC-52.
    1 context sentence
    Summary · context
    In this study the biological role of exogenous IGFs in two malignant RCC cells (Caki-2 and SK-RC-52) were investigated in vitro, and compared to the breast cancer cell line MCF-7.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 13:52 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.