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Study · In vitro (cells) · bovine · 1995

2 results

Hormonal and extracellular matrix regulation of plasminogen activator in a bovine mammary epithelial cell line.

Politis I, Zavizion B, White JH, Goldberg JJ, Baldi A, Akers RM

Endocrine1 May 1995Cited by 12 (Europe PMC)

PMID21153186 (opens in a new tab)DOI10.1007/bf03021417 (opens in a new tab)PepBankPUB-21153186
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In bovine mammary epithelial cells, Des(1‑3) IGF-I increased u-PA activity per cell.

    In plain wordsIn cells from cattle, Des(1‑3) IGF-I increased u-PA activity per cell.

    Peptide
    IGF-1 DES (des(1-3)IGF-I)
    Outcome
    Increaseu-PA activity per cell
    Study

    bovinen: not reported in source

    MAC-T mammary epithelial cells
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Not unexpectedly, insulin-like growth factor (IGF)-I, Des(1-3) IGF-I and IGF-II increased mammary epithelial u-PA activity on a per cell basis and u-PA mRNA levels, thus, mimicking the effect of insulin.
  2. 02LabIn vitro (cells)Mechanism

    In bovine mammary epithelial cells, Des(1‑3) IGF-I increased u-PA mRNA levels.

    In plain wordsIn cells from cattle, Des(1‑3) IGF-I increased u-PA mRNA levels.

    Peptide
    IGF-1 DES (des(1-3)IGF-I)
    Outcome
    Increaseu-PA mRNA
    Study

    bovinen: not reported in source

    MAC-T mammary epithelial cells
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Not unexpectedly, insulin-like growth factor (IGF)-I, Des(1-3) IGF-I and IGF-II increased mammary epithelial u-PA activity on a per cell basis and u-PA mRNA levels, thus, mimicking the effect of insulin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 13:52 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

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Publication types

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