Humanin studies: 375 papers with results
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- Cytoprotective peptide humanin binds and inhibits proapoptotic Bcl-2/Bax family protein BimEL.
Luciano F · The Journal of biological chemistry · 2005
Ex vivo tissue · mouse · 6 results
- Humanin directly protects cardiac mitochondria against dysfunction initiated by oxidative stress by decreasing complex I activity.
Thummasorn S · Mitochondrion · 2018
Ex vivo tissue · 2 results
- Protective effect of S14G-humanin against beta-amyloid induced LTP inhibition in mouse hippocampal slices.
Zhang W · Peptides · 2009
Ex vivo tissue · mouse · 3 results
- Mitochondrial-derived peptides, HNG and SHLP3, protect cochlear hair cells against gentamicin.
Lu Y · Cell death discovery · 2024
Ex vivo tissue · 4 results
- Exogenous humanin and MOTS-c function as protective agents against gentamicin-induced hair cell damage.
Waldmann D · Biochemical and biophysical research communications · 2023
Ex vivo tissue · 4 results
- Mitochondrial-derived peptide Humanin protects granulosa cells under oxidative conditions.
Conte JG · Reproduction (Cambridge, England) · 2026
Ex vivo tissue · rat · 8 results
- [Effects of humanin on elevation of intracellular calcium concentration induced by beta-amyloid peptide(31-35) in cultured cortical neurons.].
Li LM · Sheng li xue bao : [Acta physiologica Sinica] · 2009
In vitro (cells) · 3 results
- Humanin peptide suppresses apoptosis by interfering with Bax activation.
Guo B · Nature · 2003
In vitro (cells) · 7 results
- Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis.
Ikonen M · Proceedings of the National Academy of Sciences of the United States of America · 2003
In vitro (cells) · mouse · 8 results
- Mechanisms of neuroprotection by a novel rescue factor humanin from Swedish mutant amyloid precursor protein.
Hashimoto Y · Biochemical and biophysical research communications · 2001
In vitro (cells) · 5 results
- Detailed characterization of neuroprotection by a rescue factor humanin against various Alzheimer's disease-relevant insults.
Hashimoto Y · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001
In vitro (cells) · 6 results
- Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor.
Ying G · Journal of immunology (Baltimore, Md. : 1950) · 2004
In vitro (cells) · 4 results
- The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction.
Sreekumar PG · Investigative ophthalmology & visual science · 2016
In vitro (cells) · 12 results
- Humanin is expressed in human vascular walls and has a cytoprotective effect against oxidized LDL-induced oxidative stress.
Bachar AR · Cardiovascular research · 2010
In vitro (cells) · 5 results
- Mitochondrial peptides modulate mitochondrial function during cellular senescence.
Kim SJ · Aging · 2018
In vitro (cells) · 8 results
- Involvement of tyrosine kinases and STAT3 in Humanin-mediated neuroprotection.
Hashimoto Y · Life sciences · 2005
In vitro (cells) · 2 results
- N-Formylated humanin activates both formyl peptide receptor-like 1 and 2.
Harada M · Biochemical and biophysical research communications · 2004
In vitro (cells) · chinese hamster · 5 results
- Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.
Hashimoto Y · Journal of neurochemistry · 2003
In vitro (cells) · 1 result
- The neuropeptide PACAP attenuates beta-amyloid (1-42)-induced toxicity in PC12 cells.
Onoue S · Peptides · 2002
In vitro (cells) · rat · 1 result
- Humanin is an endogenous activator of chaperone-mediated autophagy.
Gong Z · The Journal of cell biology · 2018
In vitro (cells) · 6 results
- Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage.
Nashine S · Cell death & disease · 2017
In vitro (cells) · 4 results
- A humanin analog decreases oxidative stress and preserves mitochondrial integrity in cardiac myoblasts.
Klein LE · Biochemical and biophysical research communications · 2013
In vitro (cells) · rat · 8 results
- Humanin inhibits cell death of serum-deprived PC12h cells.
Kariya S · Neuroreport · 2002
In vitro (cells) · rat · 1 result
- Humanin rescues human cerebrovascular smooth muscle cells from Abeta-induced toxicity.
Jung SS · Journal of neurochemistry · 2003
In vitro (cells) · 4 results
- The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.
Hashimoto Y · The Journal of pharmacology and experimental therapeutics · 2003
In vitro (cells) · 2 results
- Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells.
Tsukamoto E · Journal of neuroscience research · 2003
In vitro (cells) · 1 result
- Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes.
Kong L · Cell reports · 2021
In vitro (cells) · 2 results
- Humanin rescues cortical neurons from prion-peptide-induced apoptosis.
Sponne I · Molecular and cellular neurosciences · 2004
In vitro (cells) · rat · 6 results
- Humanin, a Mitochondrial-Derived Peptide Released by Astrocytes, Prevents Synapse Loss in Hippocampal Neurons.
Zárate SC · Frontiers in aging neuroscience · 2019
In vitro (cells) · 5 results
- Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione.
Matsunaga D · PloS one · 2016
In vitro (cells) · 8 results
- A novel rat gene encoding a Humanin-like peptide endowed with broad neuroprotective activity.
Caricasole A · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2002
In vitro (cells) · rat and mouse · 3 results
- Neuroprotective Peptide humanin inhibits inflammatory response in astrocytes induced by lipopolysaccharide.
Zhao ST · Neurochemical research · 2013
In vitro (cells) · 5 results
- Anti-apoptotic factor humanin is expressed in the testis and prevents cell-death in leydig cells during the first wave of spermatogenesis.
Colón E · Journal of cellular physiology · 2006
In vitro (cells) · rat · 8 results
- Transplantation of Astrocytic Mitochondria Modulates Neuronal Antioxidant Defense and Neuroplasticity and Promotes Functional Recovery after Intracerebral Hemorrhage.
Tashiro R · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
In vitro (cells) · 3 results
- Protective effects of [Gly14]-Humanin on beta-amyloid-induced PC12 cell death by preventing mitochondrial dysfunction.
Jin H · Neurochemistry international · 2010
In vitro (cells) · 6 results
- Humanin prevents high glucose-induced monocyte adhesion to endothelial cells by targeting KLF2.
Wang X · Molecular immunology · 2018
In vitro (cells) · 11 results
- Humanin protects cortical neurons from ischemia and reperfusion injury by the increased activity of superoxide dismutase.
Zhao ST · Neurochemical research · 2012
In vitro (cells) · 7 results
- Humanin promotes mitochondrial biogenesis in pancreatic MIN6 β-cells.
Qin Q · Biochemical and biophysical research communications · 2018
In vitro (cells) · 8 results
- Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin.
Blasco N · Redox biology · 2018
In vitro (cells) · 2 results
- Protective effects of tetramethylpyrazine on rat retinal cell cultures.
Yang Z · Neurochemistry international · 2008
In vitro (cells) · rat · 4 results
- Humanin detected in skeletal muscles of MELAS patients: a possible new therapeutic agent.
Kariya S · Acta neuropathologica · 2005
In vitro (cells) · 5 results
- Humanin improves impaired metabolic activity and prolongs survival of serum-deprived human lymphocytes.
Kariya S · Molecular and cellular biochemistry · 2003
In vitro (cells) · 2 results
- Humanin Attenuates NMDA-Induced Excitotoxicity by Inhibiting ROS-dependent JNK/p38 MAPK Pathway.
Yang X · International journal of molecular sciences · 2018
In vitro (cells) · 7 results
- Characterization of V642I-AbetaPP-induced cytotoxicity in primary neurons.
Niikura T · Journal of neuroscience research · 2004
In vitro (cells) · 1 result
- Humanin attenuates palmitate-induced hepatic lipid accumulation and insulin resistance via AMPK-mediated suppression of the mTOR pathway.
Kwon C · Biochemical and biophysical research communications · 2020
In vitro (cells) · 10 results
- Mitochondrial Peptide Humanin Protects Silver Nanoparticles-Induced Neurotoxicity in Human Neuroblastoma Cancer Cells (SH-SY5Y).
Gurunathan S · International journal of molecular sciences · 2019
In vitro (cells) · 1 result
- Effect of humanin on decreased ATP levels of human lymphocytes harboring A3243G mutant mitochondrial DNA.
Kariya S · Neuropeptides · 2005
In vitro (cells) · 5 results
- Humanin attenuates apoptosis induced by DRPLA proteins with expanded polyglutamine stretches.
Kariya S · Journal of molecular neuroscience : MN · 2005
In vitro (cells) · rat · 2 results
- Humanin analogue, S14G-humanin, has neuroprotective effects against oxygen glucose deprivation/reoxygenation by reactivating Jak2/Stat3 signaling through the PI3K/AKT pathway.
Gao GS · Experimental and therapeutic medicine · 2017
In vitro (cells) · 7 results
- Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD).
Nashine S · Aging · 2022
In vitro (cells) · 10 results