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Study · In vitro (cells) · rat · 2002

1 result

Humanin inhibits cell death of serum-deprived PC12h cells.

Kariya S, Takahashi N, Ooba N, Kawahara M, Nakayama H, Ueno S

Neuroreport1 May 2002Cited by 65 (Europe PMC)

PMID11997711 (opens in a new tab)DOI10.1097/00001756-200205070-00034 (opens in a new tab)PepBankPUB-11997711
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    Humanin and S14G humanin protected PC12 cells from death caused by serum deprivation in MTS, caspase-3 and DNA fragmentation assays.

    In plain wordsIn cells, humanin and a changed form of it protected rat nerve-like cells from death after serum removal.

    Peptide
    Humanin
    Outcome
    DecreaseDeath of serum-deprived PC12 cells
    Study

    ratn: not reported in source

    PC12 cells
    Outcome group
    Cell viability and death · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In this study, we demonstrated, using three different methods (MTS assay, caspase-3 assay, and detection of DNA fragmentation), that both HN and HNG protect PC12 cells from death elicited by serum deprivation.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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