Humanin studies: 375 papers with results
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- Humanin rescues cultured rat cortical neurons from NMDA-induced toxicity through the alleviation of mitochondrial dysfunction.
Cui AL · Drug design, development and therapy · 2017
In vitro (cells) · rat · 4 results
- Identification of soluble WSX-1 not as a dominant-negative but as an alternative functional subunit of a receptor for an anti-Alzheimer's disease rescue factor Humanin.
Hashimoto Y · Biochemical and biophysical research communications · 2009
In vitro (cells) · 2 results
- Humanin Ameliorates Free Fatty Acid-Induced Endothelial Inflammation by Suppressing the NLRP3 Inflammasome.
Li W · ACS omega · 2020
In vitro (cells) · 8 results
- Humanin inhibits apoptosis in pituitary tumor cells through several signaling pathways including NF-κB activation.
Gottardo MF · Journal of cell communication and signaling · 2017
In vitro (cells) · 7 results
- SH3-binding protein 5 mediates the neuroprotective effect of the secreted bioactive peptide humanin by inhibiting c-Jun NH2-terminal kinase.
Takeshita Y · The Journal of biological chemistry · 2013
In vitro (cells) · 4 results
- Amino- and carboxyl-terminal mutants of presenilin 1 cause neuronal cell death through distinct toxic mechanisms: Study of 27 different presenilin 1 mutants.
Hashimoto Y · Journal of neuroscience research · 2004
In vitro (cells) · 2 results
- Protection effect of [Gly14]-Humanin from apoptosis induced by high glucose in human umbilical vein endothelial cells.
Xie Y · Diabetes research and clinical practice · 2014
In vitro (cells) · 7 results
- An AD-related neuroprotector rescues transformed rat retinal ganglion cells from CoCl₂-induced apoptosis.
Men J · Journal of molecular neuroscience : MN · 2012
In vitro (cells) · rat · 2 results
- Cytoprotective role of humanin in lens epithelial cell oxidative stress‑induced injury.
Yang H · Molecular medicine reports · 2020
In vitro (cells) · 6 results
- Interaction of Insulin-Like Growth Factor-Binding Protein 3 With Hyaluronan and Its Regulation by Humanin and CD44.
Muterspaugh R · Biochemistry · 2018
In vitro (cells) · 8 results
- Interaction of amyloid beta with humanin and acetylcholinesterase is modulated by ATP.
Atali S · FEBS open bio · 2020
In vitro (cells) · 6 results
- HNGF6A Inhibits Oxidative Stress-Induced MC3T3-E1 Cell Apoptosis and Osteoblast Phenotype Inhibition by Targeting Circ_0001843/miR-214 Pathway.
Zhu X · Calcified tissue international · 2020
In vitro (cells) · mouse · 10 results
- Gly[14]-humanin inhibits ox-LDL uptake and stimulates cholesterol efflux in macrophage-derived foam cells.
Zhu WW · Biochemical and biophysical research communications · 2017
In vitro (cells) · 6 results
- Involvement of the mitochondrial nuclease EndoG in the regulation of cell proliferation through the control of reactive oxygen species.
Blasco N · Redox biology · 2020
In vitro (cells) · 3 results
- The protective effects of S14G-humanin (HNG) against lipopolysaccharide (LPS)- induced inflammatory response in human dental pulp cells (hDPCs) mediated by the TLR4/MyD88/NF-κB pathway.
Zhang P · Bioengineered · 2021
In vitro (cells) · 10 results
- Protective effects of humanin on okadaic Acid-induced neurotoxicities in cultured cortical neurons.
Zhao J · Neurochemical research · 2014
In vitro (cells) · 5 results
- Humanin protects cortical neurons from calyculin A-induced neurotoxicities by increasing PP2A activity and SOD.
Zhao J · The International journal of neuroscience · 2021
In vitro (cells) · 5 results
- Humanin rescues cultured rat cortical neurons from NMDA-induced toxicity not by NMDA receptor.
Cui AL · TheScientificWorldJournal · 2014
In vitro (cells) · rat · 4 results
- S14G-humanin (HNG) protects retinal endothelial cells from UV-B-induced NLRP3 inflammation activation through inhibiting Egr-1.
Shi D · Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021
In vitro (cells) · 7 results
- [Gly14]-humanin restores cathepsin D function via FPRL1 and promotes autophagic degradation of Ox-LDL in HUVECs.
Ding Y · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2020
In vitro (cells) · 5 results
- Humanin suppresses receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation via AMP-activated protein kinase activation.
Kang N · The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2019
In vitro (cells) · 8 results
- Mitochondrial humanin peptide acts as a cytoprotective factor in granulosa cell survival.
Marvaldi C · Reproduction (Cambridge, England) · 2021
In vitro (cells) · 7 results
- [Gly14]-Humanin Prevents Lipid Deposition and Endothelial Cell Apoptosis in a Lectin-like Oxidized Low-density Lipoprotein Receptor-1-Dependent Manner.
Ding Y · Lipids · 2019
In vitro (cells) · 4 results
- Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling.
Cheng J · Cell reports. Medicine · 2024
In vitro (cells) · 3 results
- Cytoprotective role of S14G-humanin (HNG) in ultraviolet-B induced epidermal stem cells injury.
Wang X · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2019
In vitro (cells) · mouse · 8 results
- Effects of Humanin G (HNG) on angiogenesis and neurodegeneration markers in Age-related Macular Degeneration (AMD).
Nashine S · Mitochondrion · 2024
In vitro (cells) · 4 results
- [Gly14]-Humanin inhibits an angiotensin II-induced vascular smooth muscle cell phenotypic switch via ameliorating intracellular oxidative stress.
Xie Y · Human & experimental toxicology · 2022
In vitro (cells) · 5 results
- [Gly14]-Humanin Ameliorates High Glucose-Induced Apoptosis by Inhibiting the Expression of MicroRNA-155 in Endothelial Microparticles.
Shen MY · Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
In vitro (cells) · 6 results
- Apollon/Bruce is upregulated by Humanin.
Hashimoto Y · Molecular and cellular biochemistry · 2014
In vitro (cells) · 3 results
- Humanin protects neurons against apoptosis induced by Abeta31-35 through suppression of intrinsic pathway.
Li LM · Sheng li xue bao : [Acta physiologica Sinica] · 2010
In vitro (cells) · 5 results
- Mitochondrial-derived peptides MOTS-c and humanin attenuate dexamethasone-induced atrophy in human skeletal muscle cells.
Elhusseiny R · Physiological reports · 2026
In vitro (cells) · 9 results
- [Gly14]-Humanin ameliorates high glucose-induced endothelial senescence via SIRT6.
Li M · Scientific reports · 2024
In vitro (cells) · 3 results
- Humanin improved the rotenone-induced reactive oxygen species formation in PC12 cells by modulating the SIRT3/Nrf2/HO-1 signaling pathway.
Shan Y · Toxicology and industrial health · 2026
In vitro (cells) · 6 results
- Arsenic Promotes Intracellular Aβ(1-42) Accumulation via Enhanced APP but Reduced NEP Expression, and Indirectly Stimulates Extracellular Aβ Aggregation through AChE Induction in Differentiated SH-SY5Y Cells.
Leelaprachakul N · Biological trace element research · 2026
In vitro (cells) · 3 results
- Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alpha/WSX-1/gp130.
Hashimoto Y · Molecular biology of the cell · 2009
In vitro (cell-free) · 5 results
- The Mitochondrial-Derived Peptides, HumaninS14G and Small Humanin-like Peptide 2, Exhibit Chaperone-like Activity.
Okada AK · Scientific reports · 2017
In vitro (cell-free) · 4 results
- Zinc(II) binds to the neuroprotective peptide humanin.
Armas A · Journal of inorganic biochemistry · 2006
In vitro (cell-free) · 3 results
- Interaction structure of the complex between neuroprotective factor humanin and Alzheimer's β-amyloid peptide revealed by affinity mass spectrometry and molecular modeling.
Maftei M · Journal of peptide science : an official publication of the European Peptide Society · 2012
In vitro (cell-free) · 3 results
- Humanin decreases mitochondrial membrane permeability by inhibiting the membrane association and oligomerization of Bax and Bid proteins.
Ma ZW · Acta pharmacologica Sinica · 2018
In vitro (cell-free) · 6 results
- Humanin induces conformational changes in the apoptosis regulator BAX and sequesters it into fibers, preventing mitochondrial outer-membrane permeabilization.
Morris DL · The Journal of biological chemistry · 2019
In vitro (cell-free) · 4 results
- Humanin Peptide Binds to Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3) and Regulates Its Interaction with Importin-β.
Njomen E · Protein and peptide letters · 2015
In vitro (cell-free) · 4 results
- Humanin selectively prevents the activation of pro-apoptotic protein BID by sequestering it into fibers.
Morris DL · The Journal of biological chemistry · 2020
In vitro (cell-free) · 5 results
- Humanin peptides block calcium influx of rat hippocampal neurons by altering fibrogenesis of Abeta(1-40).
Zou P · Peptides · 2003
In vitro (cell-free) · 4 results
- Humanin Blocks the Aggregation of Amyloid-β Induced by Acetylcholinesterase, an Effect Abolished in the Presence of IGFBP-3.
Price D · Biochemistry · 2020
In vitro (cell-free) · 10 results
- Solution NMR structure and inhibitory effect against amyloid-β fibrillation of Humanin containing a d-isomerized serine residue.
Alsanousi N · Biochemical and biophysical research communications · 2016
In vitro (cell-free) · 4 results
- The Mitochondrial Peptide Humanin Targets but Does Not Denature Amyloid Oligomers in Type II Diabetes.
Levine ZA · Journal of the American Chemical Society · 2019
In vitro (cell-free) · 6 results
- Humanin structural versatility and interaction with model cerebral cortex membranes.
Pistolesi S · Biochemistry · 2009
In vitro (cell-free) · 4 results
- Using Small Peptide Segments of Amyloid-β and Humanin to Examine their Physical Interactions.
Heyl DL · Protein and peptide letters · 2019
In vitro (cell-free) · 6 results
- Interaction of the spectrin-like repeats of alpha-actinin-4 with humanin peptide.
Kigawa A · Clinical and experimental nephrology · 2004
In vitro (cell-free) · 6 results
- Humanin binds MPP8: mapping interaction sites of the peptide and protein.
Maximov VV · Journal of peptide science : an official publication of the European Peptide Society · 2013
In vitro (cell-free) · 3 results