Skip to content

Study · In vitro (cell-free) · 2013

3 results

Humanin binds MPP8: mapping interaction sites of the peptide and protein.

Maximov VV, Martynenko AV, Arman IP, Tarantul VZ

Journal of peptide science : an official publication of the European Peptide Society27 Mar 2013Cited by 6 (Europe PMC)

PMID23532874 (opens in a new tab)DOI10.1002/psc.2500 (opens in a new tab)PepBankPUB-23532874
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cell-free)Mechanism

    In co-immunoprecipitation experiments, humanin interacted with the M-phase phosphoprotein 8 (MPP8).

    In plain wordsIn lab tests, humanin was confirmed to bind to the protein MPP8.

    Peptide
    Humanin
    Outcome
    Not applicableInteraction of humanin with MPP8
    Study

    n: not reported in source

    Co-immunoprecipitation
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In the present work, we further confirmed interaction of HN with MPP8 in co-immunoprecipitation experiments
  2. 02LabIn vitro (cell-free)Mechanism

    In co-immunoprecipitation experiments, an MPP8-binding site was localized in the region between amino acids 5 and 12 of humanin.

    In plain wordsIn lab tests, the part of humanin that binds MPP8 was mapped to amino acids 5 to 12.

    Peptide
    Humanin
    Outcome
    Not applicableMPP8-binding site on humanin
    Study

    n: not reported in source

    Co-immunoprecipitation
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    localized an MPP8-binding site in the region between 5 and 12 aa. of HN.
  3. 03LabIn vitro (cell-free)Mechanism

    An MPP8 fragment (residues 431-560) was sufficient to bind humanin.

    In plain wordsIn lab tests, a part of the MPP8 protein was enough to bind humanin.

    Peptide
    Humanin
    Outcome
    Not applicableMPP8 fragment sufficient to bind humanin
    Study

    n: not reported in source

    Co-immunoprecipitation
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We have also shown that an MPP8 fragment (residues 431-560) is sufficient to bind HN.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.