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Thymosin beta-4 (human) studies: 835 papers with results

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  1. Thymosin beta 4 up-regulates miR-200a expression and induces differentiation and survival of rat brain progenitor cells.

    Santra M · Journal of neurochemistry · 2016

    Animal study (in vivo) · rat · 9 results

  2. Recombinant thymosin beta 4 can promote full-thickness cutaneous wound healing.

    Li X · Protein expression and purification · 2007

    Animal study (in vivo) · mouse · 4 results

  3. Thymosin beta4 enhances repair by organizing connective tissue and preventing the appearance of myofibroblasts.

    Ehrlich HP · Annals of the New York Academy of Sciences · 2010

    Animal study (in vivo) · rat · 7 results

  4. Neuroprotective effects of thymosin beta4 in experimental models of excitotoxicity.

    Popoli P · Annals of the New York Academy of Sciences · 2007

    Animal study (in vivo) · 3 results

  5. Effects of exogenous thymosin β4 on carbon tetrachloride-induced liver injury and fibrosis.

    Li X · Scientific reports · 2017

    Animal study (in vivo) · mouse and rat · 9 results

  6. Thymosin β4 protects C57BL/6 mice from bleomycin-induced damage in the lung.

    Conte E · European journal of clinical investigation · 2013

    Animal study (in vivo) · mouse · 8 results

  7. Thymosin β4 alleviates renal fibrosis and tubular cell apoptosis through TGF-β pathway inhibition in UUO rat models.

    Yuan J · BMC nephrology · 2017

    Animal study (in vivo) · rat · 11 results

  8. Beneficial effects of thymosin β4 on spinal cord injury in the rat.

    Cheng P · Neuropharmacology · 2014

    Animal study (in vivo) · rat · 8 results

  9. Evaluation of skeletal and cardiac muscle function after chronic administration of thymosin beta-4 in the dystrophin deficient mouse.

    Spurney CF · PloS one · 2010

    Animal study (in vivo) · mouse · 4 results

  10. Discovery of thymosin β4 as a human exerkine and growth factor.

    Gonzalez-Franquesa A · American journal of physiology. Cell physiology · 2021

    Animal study (in vivo) · mouse · 6 results

  11. RGN-259 (thymosin β4) improves clinically important dry eye efficacies in comparison with prescription drugs in a dry eye model.

    Kim CE · Scientific reports · 2018

    Animal study (in vivo) · mouse · 7 results

  12. Recombinant DTβ4-inspired porous 3D vascular graft enhanced antithrombogenicity and recruited circulating CD93+/CD34+ cells for endothelialization.

    Xiao W · Science advances · 2022

    Animal study (in vivo) · rabbit · 5 results

  13. Cardioprotection by systemic dosing of thymosin beta four following ischemic myocardial injury.

    Bao W · Frontiers in pharmacology · 2013

    Animal study (in vivo) · rat · 10 results

  14. Thymosin beta4 promotes oligodendrogenesis in the demyelinating central nervous system.

    Zhang J · Neurobiology of disease · 2016

    Animal study (in vivo) · mouse · 11 results

  15. Thymosin beta 4 improves dermal burn wound healing via downregulation of receptor of advanced glycation end products in db/db mice.

    Kim S · Biochimica et biophysica acta · 2014

    Animal study (in vivo) · mouse · 4 results

  16. Transplantation of Endothelial Progenitor Cells in Obese Diabetic Rats Following Myocardial Infarction: Role of Thymosin Beta-4.

    Poh KK · Cells · 2020

    Animal study (in vivo) · rat · 6 results

  17. Therapeutic Benefit of Extended Thymosin β4 Treatment Is Independent of Blood Glucose Level in Mice with Diabetic Peripheral Neuropathy.

    Wang L · Journal of diabetes research · 2015

    Animal study (in vivo) · mouse · 11 results

  18. Protective effects of thymosin β4 on carbon tetrachloride-induced acute hepatotoxicity in rats.

    Reyes-Gordillo K · Annals of the New York Academy of Sciences · 2012

    Animal study (in vivo) · rat · 8 results

  19. Thymosin Beta-4 and Ciprofloxacin Adjunctive Therapy Improves Pseudomonas aeruginosa-Induced Keratitis.

    Carion TW · Cells · 2018

    Animal study (in vivo) · 3 results

  20. Thymosin β4 promotes endothelial progenitor cell angiogenesis via a vascular endothelial growth factor‑dependent mechanism.

    Zhao Y · Molecular medicine reports · 2018

    Animal study (in vivo) · rat · 5 results

  21. Thymosin β4 inhibits microglia activation through microRNA 146a in neonatal rats following hypoxia injury.

    Zhou T · Neuroreport · 2015

    Animal study (in vivo) · rat · 7 results

  22. Thymosin β4 reduces IL-17-producing cells and IL-17 expression, and protects lungs from damage in bleomycin-treated mice.

    Conte E · Immunobiology · 2014

    Animal study (in vivo) · mouse · 5 results

  23. Tβ4 suppresses lincRNA-p21-mediated hepatic apoptosis and fibrosis by inhibiting PI3K-AKT-NF-κB pathway.

    Yang L · Gene · 2020

    Animal study (in vivo) · mouse · 14 results

  24. Thymosin β4 attenuates early diabetic nephropathy in a mouse model of type 2 diabetes mellitus.

    Zhu J · American journal of therapeutics · 2015

    Animal study (in vivo) · mouse · 9 results

  25. Thymosin β4 promotes the survival and angiogenesis of transplanted endothelial progenitor cells in the infarcted myocardium.

    Quan Z · International journal of molecular medicine · 2017

    Animal study (in vivo) · rat · 10 results

  26. Thymosin β4 has a major role in dermal burn wound healing that involves actin cytoskeletal remodelling via heat-shock protein 70.

    Kim S · Journal of tissue engineering and regenerative medicine · 2017

    Animal study (in vivo) · 5 results

  27. Thymosin beta-4 improves endothelial function and reparative potency of diabetic endothelial cells differentiated from patient induced pluripotent stem cells.

    Su L · Stem cell research & therapy · 2022

    Animal study (in vivo) · mouse · 11 results

  28. Thymosin beta 4 induces significant changes in the plasma miRNA profile following severe traumatic brain injury in the rat lateral fluid percussion injury model.

    Osei J · Expert opinion on biological therapy · 2018

    Animal study (in vivo) · rat · 4 results

  29. Pegylated and liposomal doxorubicin is associated with high mortality and causes limited cardiotoxicity in mice.

    Stark C · BMC research notes · 2018

    Animal study (in vivo) · mouse · 2 results

  30. Omental grafting: a cell-based therapy for blood vessel repair.

    Shelton EL · Journal of tissue engineering and regenerative medicine · 2013

    Animal study (in vivo) · mouse · 6 results

  31. Promoting effects of thymosin β4 on granulation tissue and new bone formation after tooth extraction in rats.

    Matsuo K · Oral surgery, oral medicine, oral pathology and oral radiology · 2012

    Animal study (in vivo) · rat · 4 results

  32. Thymosin β4 promotes autophagy and repair via HIF-1α stabilization in chronic granulomatous disease.

    Renga G · Life science alliance · 2019

    Animal study (in vivo) · mouse · 6 results

  33. Thymosin β4 attenuates liver fibrosis via suppressing Notch signaling.

    Hong Y · Biochemical and biophysical research communications · 2017

    Animal study (in vivo) · mouse · 4 results

  34. Thymosin β4 administration enhances fracture healing in mice.

    Brady RD · Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2014

    Animal study (in vivo) · mouse · 7 results

  35. Thymosin beta 4 ameliorates hyperglycemia and improves insulin resistance of KK Cg-Ay/J mouse.

    Zhu J · Diabetes research and clinical practice · 2012

    Animal study (in vivo) · mouse · 6 results

  36. Recombinant Human Thymosin β4 (rhTβ4) Modulates the Anti-Inflammatory Responses to Alleviate Benzalkonium Chloride (BAC)-Induced Dry Eye Disease.

    Zhai Y · International journal of molecular sciences · 2022

    Animal study (in vivo) · mouse · 6 results

  37. Protective effects of thymosin β4 in a mouse model of lung fibrosis.

    Conte E · Annals of the New York Academy of Sciences · 2012

    Animal study (in vivo) · mouse · 2 results

  38. Adjunctive Thymosin Beta-4 Treatment Influences PMN Effector Cell Function during Pseudomonas aeruginosa-Induced Corneal Infection.

    Wang Y · Cells · 2021

    Animal study (in vivo) · mouse · 4 results

  39. Reversal of second-hand cigarette smoke-induced impairment of corneal wound healing by thymosin beta4 combined with anti-inflammatory agents.

    Yuan H · Investigative ophthalmology & visual science · 2010

    Animal study (in vivo) · 4 results

  40. Protective Effect of Thymosin β4 against Abdominal Aortic Ischemia-Reperfusion-Induced Acute Lung Injury in Rats.

    Yaman OM · Medicina (Kaunas, Lithuania) · 2019

    Animal study (in vivo) · rat · 4 results

  41. miR-146a mediates thymosin β4 induced neurovascular remodeling of diabetic peripheral neuropathy in type-II diabetic mice.

    Wang L · Brain research · 2019

    Animal study (in vivo) · mouse · 14 results

  42. Recombinant Human Thymosin Beta-4 Protects against Mouse Coronavirus Infection.

    Yu R · Mediators of inflammation · 2021

    Animal study (in vivo) · mouse · 5 results

  43. Anti-inflammatory effects of glycine thymosin β4 eye drops in experimental dry eye.

    Jin R · Biomedical reports · 2020

    Animal study (in vivo) · mouse · 6 results

  44. Systemic Dosing of Thymosin Beta 4 before and after Ischemia Does Not Attenuate Global Myocardial Ischemia-Reperfusion Injury in Pigs.

    Stark CK · Frontiers in pharmacology · 2016

    Animal study (in vivo) · pig · 7 results

  45. Novel modulators of hepatosteatosis, inflammation and fibrogenesis.

    Lakshman MR · Hepatology international · 2014

    Animal study (in vivo) · rat · 8 results

  46. Thymosin β4 Alleviates Autoimmune Dacryoadenitis via Suppressing Th17 Cell Response.

    Zhao X · Investigative ophthalmology & visual science · 2023

    Animal study (in vivo) · rabbit · 8 results

  47. The Effect of Thymosin beta4 on the Survival of Autologous Fat Grafting: A Preliminary Study.

    Qu Y · Aesthetic surgery journal · 2020

    Animal study (in vivo) · rabbit · 6 results

  48. Thymosin β4-Enhancing Therapeutic Efficacy of Human Adipose-Derived Stem Cells in Mouse Ischemic Hindlimb Model.

    Kim JH · International journal of molecular sciences · 2020

    Animal study (in vivo) · mouse · 9 results

  49. Highly effective biosynthesis of N-acetylated human thymosin β4 (Tβ4) in Escherichia coli.

    Yu R · Artificial cells, nanomedicine, and biotechnology · 2018

    Animal study (in vivo) · rat · 5 results

  50. Function of Thymosin Beta-4 in Ethanol-Induced Microglial Activation.

    Zhang J · Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2016

    Animal study (in vivo) · mouse · 11 results

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