Thymosin beta-4 (human) studies: 835 papers with results
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- Thymosin beta 4 synergizes with human granulocyte-macrophage colony-stimulating factor in maintaining bone marrow proliferation.
Moscinski LC · Immunopharmacology · 1993
Animal study (in vivo) · mouse · 6 results
- Thymosin beta 4 prevents systemic lipopolysaccharide-induced plaque load in middle-age APP/PS1 mice.
Othman O · International immunopharmacology · 2023
Animal study (in vivo) · mouse · 4 results
- Thymosin beta 4 as an Alzheimer disease intervention target identified using human brain organoids.
Zeng PM · Stem cell reports · 2025
Animal study (in vivo) · mouse · 5 results
- Upregulated Tβ4 expression in inflammatory bowel disease impairs the intestinal mucus barrier by inhibiting autophagy in mice.
Hao M · Experimental cell research · 2024
Animal study (in vivo) · mouse · 8 results
- Thymosin beta-4 prenatal administration improves fetal development and halts side effects due to preterm delivery.
Faa G · European review for medical and pharmacological sciences · 2021
Animal study (in vivo) · mouse · 6 results
- Thymosin β4 enhances the healing of medial collateral ligament injury in rat.
Xu B · Regulatory peptides · 2013
Animal study (in vivo) · rat · 4 results
- Prelimbic cortex to ventral tegmental area projection regulates early social isolation stress-potentiated heroin seeking in mice.
Wang Y · Nature communications · 2025
Animal study (in vivo) · mouse · 3 results
- Plasmacytoid dendritic cells alleviate allergic asthma via airway epithelial cell-dependent thymosin β4 expression.
Li Y · The Journal of allergy and clinical immunology · 2025
Animal study (in vivo) · mouse · 11 results
- Detection and quantification of the metabolite Ac-Tβ1-14 in in vitro experiments and urine of rats treated with Ac-Tβ4: A potential biomarker of Ac-Tβ4 for doping tests.
Rahaman KA · Drug testing and analysis · 2023
Animal study (in vivo) · rat · 8 results
- Exogenous Thymosin Beta 4 Suppresses IPF-Lung Cancer in Mice: Possibly Associated with Its Inhibitory Effect on the JAK2/STAT3 Signaling Pathway.
Yu R · International journal of molecular sciences · 2023
Animal study (in vivo) · mouse · 5 results
- Effects of thymosin β4 on the bone formation of calvarial defects in rats.
Adachi K · Journal of prosthodontic research · 2013
Animal study (in vivo) · wistar rat · 4 results
- The Escherichia coli-derived thymosin β4 concatemer promotes cell proliferation and healing wound in mice.
Wang X · BioMed research international · 2013
Animal study (in vivo) · mouse · 3 results
- Effects of thymosin β4 on a rat model of severe acute pancreatitis.
He X · Experimental and therapeutic medicine · 2015
Animal study (in vivo) · rat · 7 results
- Thymosin β4 released by mast cells under stress conditions impairs intestinal epithelial barrier via IL22RA1/JAK1/STAT3 signaling in irritable bowel syndrome.
Sun YS · World journal of gastroenterology · 2025
Animal study (in vivo) · mouse and rat · 8 results
- Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Wang X · Transplantation and cellular therapy · 2023
Animal study (in vivo) · mouse · 26 results
- The use of angiogenic-antimicrobial agents in experimental wounds in animals: problems and solutions.
Suman P · Annals of the New York Academy of Sciences · 2012
Animal study (in vivo) · rat · 5 results
- Thymosin β4 alleviates sepsis-associated acute kidney injury by suppressing MAPK signaling pathway.
Ouyang X · Clinical science (London, England : 1979) · 2026
Animal study (in vivo) · mouse · 7 results
- Thymosin β4 Regulates Tissue Inflammatory Response in Mouse Nonalcoholic Fatty Liver Disease by Promoting Macrophage M2-Type Polarization.
Zhu Z · Journal of inflammation research · 2025
Animal study (in vivo) · mouse · 7 results
- Thymosin Beta-4 Modulates Cardiac Remodeling by Regulating ROCK1 Expression in Adult Mammals.
Maar K · International journal of molecular sciences · 2025
Animal study (in vivo) · mouse · 5 results
- Effects of Thymosin β4 on Myocardial Apoptosis in Burned Rats.
Wu X · Journal of healthcare engineering · 2022
Animal study (in vivo) · rat · 3 results
- Protection effect of thymosin β4 on ethanol injury in corneal stromal keratocyte.
Liu J · BMC ophthalmology · 2022
Animal study (in vivo) · mouse · 9 results
- A Tobacco-Derived Thymosin β4 Concatemer Promotes Cell Proliferation and Wound Healing in Mice.
Janarthini R · BioMed research international · 2016
Animal study (in vivo) · mouse · 3 results
- Efficiency of recombinant thymosin β4 in spontaneous mouse model of chronic dermatitis.
Moiseeva EV · Bulletin of experimental biology and medicine · 2015
Animal study (in vivo) · mouse · 2 results
- Recombinant human Thymosin β4 ameliorates experimental colitis and intestinal fibrosis through suppression of mineralocorticoid receptor signaling.
Zhao TR · Molecular biomedicine · 2026
Animal study (in vivo) · mouse · 10 results
- Thymosin β4 Mitigates Acute Cerebral Infarction Via Inhibition of the TLR4/NF-κB Pathway and Suppression of Neuronal Pyroptosis.
Zhang Z · Applied biochemistry and biotechnology · 2026
Animal study (in vivo) · rat · 14 results
- Recombinant Human Thymosin β4 Attenuates Endotoxemia-Induced ALI and EAE by Suppressing Inflammatory and Oxidative Responses.
Ye Y · Biomolecules · 2026
Animal study (in vivo) · mouse · 10 results
- PEGylated thymosin β4 is a thiol-site-specific prodrug treating myocardial infarction in vivo.
Peng H · Bioengineering & translational medicine · 2026
Animal study (in vivo) · 4 results
- Inhaled exogenous thymosin beta 4 suppresses bleomycin-induced pulmonary fibrosis in mice via TGF-β1 signalling pathway.
Yu R · The Journal of pharmacy and pharmacology · 2025
Animal study (in vivo) · mouse · 6 results
- Activation of pro-resolving pathways mediate the therapeutic effects of thymosin beta-4 during Pseudomonas aeruginosa-induced keratitis.
Wang Y · Frontiers in immunology · 2024
Animal study (in vivo) · 4 results
- Enhancing fat graft survival: thymosin beta-4 facilitates mitochondrial transfer from ADSCs via tunneling nanotubes by upregulating the Rac/F-actin pathway.
Zhang X · Free radical biology & medicine · 2025
Other design · 7 results
- Thymosin beta4 sequesters actin in cystic fibrosis sputum and decreases sputum cohesivity in vitro.
Rubin BK · Chest · 2006
Ex vivo tissue · 7 results
- Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization.
Smart N · Nature · 2007
Ex vivo tissue · 5 results
- Thymosin stimulates secretion of luteinizing hormone-releasing factor.
Rebar RW · Science (New York, N.Y.) · 1981
Ex vivo tissue · rat · 2 results
- Thymosin beta4 enhances endothelial cell differentiation and angiogenesis.
Grant DS · Angiogenesis · 1999
Ex vivo tissue · 8 results
- The actin binding site on thymosin beta4 promotes angiogenesis.
Philp D · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2003
Ex vivo tissue · chicken · 7 results
- The anti-inflammatory peptide Ac-SDKP is released from thymosin-β4 by renal meprin-α and prolyl oligopeptidase.
Kumar N · American journal of physiology. Renal physiology · 2016
Ex vivo tissue · mouse and rat · 3 results
- The role of DNA and actin polymers on the polymer structure and rheology of cystic fibrosis sputum and depolymerization by gelsolin or thymosin beta 4.
Kater A · Annals of the New York Academy of Sciences · 2007
Ex vivo tissue · 3 results
- Thymosins alpha 1 and beta 4 potentiate the antigen-presenting capacity of macrophages.
Tzehoval E · Immunopharmacology · 1989
Ex vivo tissue · mouse · 10 results
- Derivation of epicardium-derived progenitor cells (EPDCs) from adult epicardium.
Smart N · Current protocols in stem cell biology · 2009
Ex vivo tissue · 1 result
- Epicardial slices: an innovative 3D organotypic model to study epicardial cell physiology and activation.
Maselli D · NPJ Regenerative medicine · 2022
Ex vivo tissue · pig · 4 results
- Formation of acetyl-Ser-Asp-Lys-Pro, a new regulator of the hematopoietic system, through enzymatic processing of thymosin beta 4.
Lenfant M · Annals of the New York Academy of Sciences · 1991
Ex vivo tissue · 4 results
- Ectopic Expression of Human Thymosin β4 Confers Resistance to Legionella pneumophila during Pulmonary and Systemic Infection in Mice.
Park B · Infection and immunity · 2021
Ex vivo tissue · mouse · 13 results
- Thymosin beta-4 - A potential tool in healing middle ear lesions in adult mammals.
Bako P · International immunopharmacology · 2023
Ex vivo tissue · mouse · 2 results
- Development of an analytical HPLC methodology to study the effects of thymosin β4 on actin in sputum of cystic fibrosis patients.
Badamchian M · Annals of the New York Academy of Sciences · 2012
Ex vivo tissue · 4 results
- Thymosin alpha 1 and thymosin beta 4 modulate human colonic lamina propria lymphocyte function.
Elitsur Y · Immunopharmacology · 1990
In vitro (cells) · 6 results
- Antimicrobial peptides from human platelets.
Tang YQ · Infection and immunity · 2002
In vitro (cells) · e. coli, s. aureus and c. albicans · 5 results
- The actin cytoskeleton is required for receptor-mediated endocytosis in mammalian cells.
Lamaze C · The Journal of biological chemistry · 1997
In vitro (cells) · 3 results
- Thymosin beta 4 suppression of corneal NFkappaB: a potential anti-inflammatory pathway.
Sosne G · Experimental eye research · 2007
In vitro (cells) · 4 results
- Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells.
Sanders MC · Proceedings of the National Academy of Sciences of the United States of America · 1992
In vitro (cells) · 2 results
- Involvement of thymosin beta 4 and endoproteinase Asp-N in the biosynthesis of the tetrapeptide AcSerAspLysPro a regulator of the hematopoietic system.
Grillon C · FEBS letters · 1990
In vitro (cells) · 3 results