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Study · Animal study (in vivo) · mouse · 2012

2 results

Protective effects of thymosin β4 in a mouse model of lung fibrosis.

Conte E, Genovese T, Gili E, Esposito E, Iemmolo M, Fruciano M, Fagone E, Pistorio MP, Crimi N, Cuzzocrea S, Vancheri C

Annals of the New York Academy of Sciences1 Oct 2012Cited by 13 (Europe PMC)

PMID23045972 (opens in a new tab)DOI10.1111/j.1749-6632.2012.06694.x (opens in a new tab)PepBankPUB-23045972
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice with bleomycin-induced lung damage, thymosin beta‑4 treatment halted the inflammatory process.

    In plain wordsIn mice with lung damage from bleomycin, thymosin beta‑4 halted the inflammation.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    DecreaseInflammatory process in bleomycin-induced lung damage
    Study

    mousen: not reported in source

    Bleomycin-induced lung injury
    Outcome group
    Inflammation markers · Respiratory
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We have observed significant protective effects of Tβ4 on bleomycin-induced lung damage, the main outcomes being the halting of the inflammatory process and a substantial reduction of histological evidence of lung injury.
    1 context sentence
    Summary · context
    In an ongoing study, we have explored the putative Tβ4 protective role in the lung context by utilizing a well-known in vivo model.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In mice with bleomycin-induced lung damage, thymosin beta‑4 treatment substantially reduced histological evidence of lung injury.

    In plain wordsIn mice with lung damage from bleomycin, thymosin beta‑4 clearly reduced the tissue signs of lung injury.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    DecreaseHistological evidence of lung injury
    Study

    mousen: not reported in source

    Bleomycin-induced lung injury
    Outcome group
    Lung injury and fibrosis · Respiratory
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We have observed significant protective effects of Tβ4 on bleomycin-induced lung damage, the main outcomes being the halting of the inflammatory process and a substantial reduction of histological evidence of lung injury.
    1 context sentence
    Summary · context
    In an ongoing study, we have explored the putative Tβ4 protective role in the lung context by utilizing a well-known in vivo model.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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