The Effect of Thymosin beta4 on the Survival of Autologous Fat Grafting: A Preliminary Study.

Qu Y, Wang Q, Fu S, Guo X, Luan J, Mu D

Aesthetic surgery journal1 Aug 2020Cited by 9 (Europe PMC)

PMID32144415DOI10.1093/asj/sjaa062PepBankPUB-32144415

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In rabbits, fat grafts mixed with Tβ4 showed better volume retention than grafts with buffer.
In plain wordsIn rabbits, fat grafts mixed with Tβ4 kept more volume than grafts with buffer only.
Peptide
Thymosin beta-4 (human)
Outcome
IncreaseFat graft volume retention
Study
rabbitn: not reported in source
autologous fat grafts in rabbit ears
Comparator
Phosphate-buffered saline (blank control)
Outcome group
Wound healing · Skin and wound
Studied dose
5 and 10 μg/mL · premixed into the fat graftAs given in this study (rabbit).
Source sentences
Summary
The fat grafts in the Tß4-treated groups showed better volume and weight retention, greater adipose tissue integrity, adipocyte viability, and angiogenesis.
2 context sentences(design, population, supporting numbers)
Summary · context
Adipose tissue premixed exogenous Tß4 were transplanted into rabbit ears.
Summary · context
Rabbits were randomly assigned to 3 groups: group A, 5 μg/mL Tß4; group B, 10 μg/mL Tß4; and group C, phosphate-buffered saline buffer as a blank control.
Report a problemFND-3214441501
02AnimalAnimal study (in vivo)Efficacy outcome
In rabbits, fat grafts mixed with Tβ4 showed better weight retention than grafts with buffer.
In plain wordsIn rabbits, fat grafts mixed with Tβ4 kept more weight than grafts with buffer only.
Peptide
Thymosin beta-4 (human)
Outcome
IncreaseFat graft weight retention
Study
rabbitn: not reported in source
autologous fat grafts in rabbit ears
Comparator
Phosphate-buffered saline (blank control)
Outcome group
Wound healing · Skin and wound
Studied dose
5 and 10 μg/mL · premixed into the fat graftAs given in this study (rabbit).
Source sentences
Summary
The fat grafts in the Tß4-treated groups showed better volume and weight retention, greater adipose tissue integrity, adipocyte viability, and angiogenesis.
2 context sentences(design, population, supporting numbers)
Summary · context
Adipose tissue premixed exogenous Tß4 were transplanted into rabbit ears.
Summary · context
Rabbits were randomly assigned to 3 groups: group A, 5 μg/mL Tß4; group B, 10 μg/mL Tß4; and group C, phosphate-buffered saline buffer as a blank control.
Report a problemFND-3214441502
03AnimalAnimal study (in vivo)Efficacy outcome
In rabbits, fat grafts mixed with Tβ4 showed greater adipose tissue integrity than grafts with buffer.
In plain wordsIn rabbits, fat grafts mixed with Tβ4 kept their structure better than grafts with buffer only.
Peptide
Thymosin beta-4 (human)
Outcome
IncreaseAdipose tissue integrity
Study
rabbitn: not reported in source
autologous fat grafts in rabbit ears
Comparator
Phosphate-buffered saline (blank control)
Outcome group
Wound healing · Skin and wound
Studied dose
5 and 10 μg/mL · premixed into the fat graftAs given in this study (rabbit).
Source sentences
Summary
The fat grafts in the Tß4-treated groups showed better volume and weight retention, greater adipose tissue integrity, adipocyte viability, and angiogenesis.
2 context sentences(design, population, supporting numbers)
Summary · context
Adipose tissue premixed exogenous Tß4 were transplanted into rabbit ears.
Summary · context
Rabbits were randomly assigned to 3 groups: group A, 5 μg/mL Tß4; group B, 10 μg/mL Tß4; and group C, phosphate-buffered saline buffer as a blank control.
Report a problemFND-3214441503
04AnimalAnimal study (in vivo)Efficacy outcome
In rabbits, fat grafts mixed with Tβ4 showed greater adipocyte viability than grafts with buffer.
In plain wordsIn rabbits, fat grafts mixed with Tβ4 had more living fat cells than grafts with buffer only.
Peptide
Thymosin beta-4 (human)
Outcome
IncreaseAdipocyte viability
Study
rabbitn: not reported in source
autologous fat grafts in rabbit ears
Comparator
Phosphate-buffered saline (blank control)
Outcome group
Wound healing · Skin and wound
Studied dose
5 and 10 μg/mL · premixed into the fat graftAs given in this study (rabbit).
Source sentences
Summary
The fat grafts in the Tß4-treated groups showed better volume and weight retention, greater adipose tissue integrity, adipocyte viability, and angiogenesis.
2 context sentences(design, population, supporting numbers)
Summary · context
Adipose tissue premixed exogenous Tß4 were transplanted into rabbit ears.
Summary · context
Rabbits were randomly assigned to 3 groups: group A, 5 μg/mL Tß4; group B, 10 μg/mL Tß4; and group C, phosphate-buffered saline buffer as a blank control.
Report a problemFND-3214441504
05AnimalAnimal study (in vivo)Efficacy outcome
In rabbits, fat grafts mixed with Tβ4 showed greater angiogenesis than grafts with buffer.
In plain wordsIn rabbits, fat grafts mixed with Tβ4 grew more new blood vessels than grafts with buffer only.
Peptide
Thymosin beta-4 (human)
Outcome
IncreaseGraft angiogenesis
Study
rabbitn: not reported in source
autologous fat grafts in rabbit ears
Comparator
Phosphate-buffered saline (blank control)
Outcome group
Angiogenesis · Skin and wound
Studied dose
5 and 10 μg/mL · premixed into the fat graftAs given in this study (rabbit).
Source sentences
Summary
The fat grafts in the Tß4-treated groups showed better volume and weight retention, greater adipose tissue integrity, adipocyte viability, and angiogenesis.
2 context sentences(design, population, supporting numbers)
Summary · context
Adipose tissue premixed exogenous Tß4 were transplanted into rabbit ears.
Summary · context
Rabbits were randomly assigned to 3 groups: group A, 5 μg/mL Tß4; group B, 10 μg/mL Tß4; and group C, phosphate-buffered saline buffer as a blank control.
Report a problemFND-3214441505
06AnimalAnimal study (in vivo)Efficacy outcome
In rabbits, dynamic contrast-enhanced MRI showed that Tβ4-treated groups had increased microcirculation perfusion of the grafts.
In plain wordsIn rabbits, scans showed more blood flow in fat grafts treated with Tβ4 than in grafts with buffer only.
Peptide
Thymosin beta-4 (human)
Outcome
IncreaseGraft microcirculation perfusion on DCE-MRI
Study
rabbitn: not reported in source
autologous fat grafts in rabbit ears
Comparator
Phosphate-buffered saline (blank control)
Outcome group
Angiogenesis · Skin and wound
Studied dose
5 and 10 μg/mL · premixed into the fat graftAs given in this study (rabbit).
Source sentences
Summary
The results of dynamic contrast-enhanced magnetic resonance imaging also showed that the experimental groups increased microcirculation perfusion of the grafts.
2 context sentences(design, population, supporting numbers)
Summary · context
Adipose tissue premixed exogenous Tß4 were transplanted into rabbit ears.
Summary · context
Rabbits were randomly assigned to 3 groups: group A, 5 μg/mL Tß4; group B, 10 μg/mL Tß4; and group C, phosphate-buffered saline buffer as a blank control.
Report a problemFND-3214441506

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
13 Oct 2026, 01:52 UTC
Study results updated
Version 1
12 Oct 2026, 18:17 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

PepBank is a research reference. Talk to a doctor before you use any peptide.