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NMN (nicotinamide mononucleotide) studies: 217 papers with results

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  1. Nicotinamide Mononucleotide Prevents Free Fatty Acid-Induced Reduction in Glucose Tolerance by Decreasing Insulin Clearance.

    Nahle A · International journal of molecular sciences · 2021

    Animal study (in vivo) · mouse · 5 results

  2. Nicotinamide Mononucleotide Alleviates Bile Acid Metabolism and Hormonal Dysregulation in Letrozole-Induced PCOS Mice.

    Ren C · Biology · 2024

    Animal study (in vivo) · mouse · 7 results

  3. Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment.

    Whitson JA · GeroScience · 2022

    Animal study (in vivo) · mouse · 3 results

  4. β-Nicotinamide mononucleotide supplementation prolongs the lifespan of prematurely aged mice and protects colon function in ageing mice.

    Gu Y · Food & function · 2024

    Animal study (in vivo) · mouse · 17 results

  5. Dietary NMN supplementation enhances motor and NMJ function in ALS.

    Lundt S · Experimental neurology · 2024

    Animal study (in vivo) · mouse · 12 results

  6. NAMPT-mediated NAD+ biosynthesis suppresses activation of hepatic stellate cells and protects against CCl4-induced liver fibrosis in mice.

    Xu L · Human & experimental toxicology · 2021

    Animal study (in vivo) · mouse · 2 results

  7. Subacute Toxicity Study of Nicotinamide Mononucleotide via Oral Administration.

    You Y · Frontiers in pharmacology · 2020

    Animal study (in vivo) · dog and mouse · 5 results

  8. Nicotinamide mononucleotide supplementation improves oocyte developmental competence in different ovarian damage conditions.

    Ramírez-Martín N · American journal of obstetrics and gynecology · 2025

    Animal study (in vivo) · mouse · 19 results

  9. Nicotinamide Mononucleotide Improves Spermatogenic Disorders in Aluminum-Exposed Rats by Modulating the Glycolytic Pathway.

    Nong W · Biological trace element research · 2024

    Animal study (in vivo) · rat · 6 results

  10. Bazi Bushen capsule alleviates skin photoaging by targeting the KEAP1-NRF2 pathway.

    Jiang Y · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2025

    Animal study (in vivo) · mouse · 3 results

  11. NMN improves cardiac function in SIRT3 knockout mice via the SIRT1/PGC-1α pathway.

    Zhao X · Scientific reports · 2025

    Animal study (in vivo) · mouse · 9 results

  12. Nicotinamide mononucleotide ameliorates ionizing radiation-induced spermatogenic dysfunction in mice by modulating the glycolytic pathway.

    Yang W · Acta biochimica et biophysica Sinica · 2024

    Animal study (in vivo) · mouse · 13 results

  13. Supplementation of nicotinamide mononucleotide diminishes COX-2 associated inflammatory responses in macrophages by activating kynurenine/AhR signaling.

    Liu J · Free radical biology & medicine · 2024

    Animal study (in vivo) · mouse · 7 results

  14. Distribution of Nicotinamide Mononucleotide after Intravenous Injection in Normal and Ischemic Stroke Mice.

    Zheng SL · Current pharmaceutical biotechnology · 2023

    Animal study (in vivo) · mouse · 11 results

  15. Nicotinamide mononucleotide ameliorates acute lung injury by inducing mitonuclear protein imbalance and activating the UPRmt.

    Du SH · Experimental biology and medicine (Maywood, N.J.) · 2022

    Animal study (in vivo) · mouse · 11 results

  16. Nicotinamide mononucleotide ameliorates hypertriglyceridemia pancreatitis via NAD+/SIRT1-mediated TXNIP suppression and NOTCH pathway for accelerated repair-associated processes.

    Duan H · International immunopharmacology · 2025

    Animal study (in vivo) · mouse · 12 results

  17. Nicotinamide mononucleotide supplementation ameliorates testicular damage induced by ischemia-reperfusion through reshaping macrophage and neutrophil inflammatory properties.

    Mou H · International immunopharmacology · 2025

    Animal study (in vivo) · mouse · 12 results

  18. β-Nicotinamide Mononucleotide Alleviates Sepsis-associated Acute Kidney Injury by Activating NAD+/SIRT3 Signaling.

    Sun C · Cell biochemistry and biophysics · 2025

    Animal study (in vivo) · mouse · 7 results

  19. Nicotinamide Mononucleotide Improves Endometrial Homeostasis in a Rat Model of Polycystic Ovary Syndrome by Decreasing Insulin Resistance and Regulating the Glylytic Pathway.

    Zhang W · Molecular nutrition & food research · 2024

    Animal study (in vivo) · rat · 9 results

  20. Long-Term Administration of Nicotinamide Mononucleotide Mitigates High-Fat-Diet-Induced Physiological Decline in Aging Mice.

    Zhou AJ · The Journal of nutrition · 2025

    Animal study (in vivo) · mouse · 9 results

  21. Nicotinamide Mononucleotide Supplementation Alleviates Doxorubicin-Induced Multi-Organ Fibrosis.

    Wen F · International journal of molecular sciences · 2024

    Animal study (in vivo) · mouse · 4 results

  22. Nicotinamide mononucleotide pretreatment improves long-term isoflurane anesthesia-induced cognitive impairment in mice.

    Xu J · Behavioural brain research · 2024

    Animal study (in vivo) · mouse · 5 results

  23. Pretreatment with nicotinamide mononucleotide increases the effect of ischaemic postconditioning on cardioprotection and mitochondrial function following ex vivo myocardial reperfusion injury in aged rats.

    Rajabi M · Clinical and experimental pharmacology & physiology · 2022

    Animal study (in vivo) · rat · 12 results

  24. β-Nicotinamide Mononucleotide Enhances Skin Barrier Function and Attenuates UV-B-Induced Photoaging in Mice.

    Kim SJ · Antioxidants (Basel, Switzerland) · 2025

    Animal study (in vivo) · mouse · 17 results

  25. Nicotinamide mononucleotide protects STAT1 from oxidative stress-induced degradation to prevent colorectal tumorigenesis.

    Li T · MedComm · 2024

    Animal study (in vivo) · mouse · 4 results

  26. Spatial regulation of NMN supplementation on brain lipid metabolism upon subacute and sub-chronic PM exposure in C57BL/6 mice.

    Jiang Y · Particle and fibre toxicology · 2024

    Animal study (in vivo) · mouse · 10 results

  27. Nicotinamide mononucleotide ameliorates impaired testicular spermatogenesis in uranium-exposed mice by modulating glycolytic pathways.

    Wu H · Toxicological sciences : an official journal of the Society of Toxicology · 2025

    Animal study (in vivo) · mouse · 1 result

  28. β-Nicotinamide mononucleotide protects against hypervirulent Klebsiella pneumoniae bloodstream infection and liver injury.

    Cao Z · mSphere · 2025

    Animal study (in vivo) · mouse · 11 results

  29. Oral nicotinamide mononucleotide (NMN) increases tissue NAD+ content in mice but neither NMN nor Polypodium leucotomos protect against UVR-induced skin cancer.

    Pihl C · Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025

    Animal study (in vivo) · mouse · 7 results

  30. Identification of adrenergic presynaptic and postsynaptic protein locations at neuromuscular junctions, their decrease during aging, and recovery by nicotinamide mononucleotide administration.

    Takeno K · Neuroreport · 2024

    Animal study (in vivo) · mouse · 3 results

  31. Deacetylation via SIRT2 prevents keratin-mutation-associated injury and keratin aggregation.

    Sun J · JCI insight · 2023

    Animal study (in vivo) · mouse · 2 results

  32. Nicotinamide mononucleotide supplementation mitigates osteopenia induced by modeled microgravity in rats.

    Huang Y · Cell stress & chaperones · 2023

    Animal study (in vivo) · rat · 14 results

  33. Nicotinamide mononucleotide treatment improves spermatogenesis in obese mice by reducing lysine acetylation of lactate dehydrogenase C.

    Liu K · Communications biology · 2025

    Animal study (in vivo) · mouse · 7 results

  34. Effects of Nicotinamide Mononucleotide Supplementation and Aerobic Exercise on Metabolic Health and Physical Performance in Aged Mice.

    Hsu YJ · Nutrients · 2025

    Animal study (in vivo) · mouse · 11 results

  35. Nicotinamide mononucleotide protects against diabetic nephropathy via IL-6/Rab5-mediated crosstalk between proximal tubular epithelial cells and podocytes.

    Zha DQ · World journal of diabetes · 2025

    Animal study (in vivo) · mouse · 9 results

  36. Nicotinamide mononucleotide protects ovarian function and oocyte developmental competence during chemotherapy.

    Shen L · Journal of ovarian research · 2025

    Animal study (in vivo) · mouse · 13 results

  37. Nicotinamide Mononucleotide Alleviates Aging Defects in Hutchinson-Gilford Progeria Syndrome.

    Xu Y · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025

    Animal study (in vivo) · mouse · 8 results

  38. Administration of nicotinamide mononucleotide suppresses the progression of age-related hearing loss in mice.

    Hattori K · Hearing research · 2025

    Animal study (in vivo) · mouse · 3 results

  39. Administration of β-Nicotinamide Mononucleotide Attenuates Myocardial Dysfunction in Tail-Suspended Mice.

    Gu W · Journal of cardiovascular pharmacology and therapeutics · 2025

    Animal study (in vivo) · mouse · 4 results

  40. Administration of Nicotinamide Mononucleotide Mitigates the HIV Nef-Induced Metabolic and Pathological Changes in the Heart.

    Kondrachuk O · Cells · 2026

    Animal study (in vivo) · mouse · 3 results

  41. NMN protects cisplatin-associated AKI via NAD+/SIRT1 pathway.

    Wen Z · Frontiers in immunology · 2026

    Animal study (in vivo) · mouse · 13 results

  42. Nicotinamide mononucleotide improves spermatogenesis in aluminium-exposed mice by inhibiting NLRP3-mediated pyroptosis.

    Nong W · PloS one · 2026

    Animal study (in vivo) · mouse · 14 results

  43. β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD+/SIRT1 signaling pathways.

    Yang X · Hereditas · 2025

    Animal study (in vivo) · mouse · 18 results

  44. Nicotinamide mononucleotide suppresses cellular senescence and increases aquaporin 5 expression in the submandibular gland of aged male mice to ameliorate aging-related dry mouth.

    Wakabayashi J · Biogerontology · 2024

    Animal study (in vivo) · mouse · 6 results

  45. Effects of Combined Treatment with Compounds Affecting Mitochondria on Physiological Parameters in Old Monkey.

    Klots IN · Bulletin of experimental biology and medicine · 2022

    Animal study (in vivo) · macaca mulatta · 7 results

  46. Nicotinamide mononucleotide supplementation improves polycystic ovary syndrome by activating silent regulatory protein 2 mediated lactate dehydrogenase A lysine 119 deacetylation to enhance glycolytic activity.

    Zhang Z · International journal of biological macromolecules · 2026

    Animal study (in vivo) · rat · 10 results

  47. Nicotinamide Mononucleotide Ameliorates Myocardial Fibrosis in Diabetic Mice Possibly by Modulating SIRT3 to Deacetylate GSK3β and Thereby Reducing the Phosphorylation of Smad3.

    Ma Z · Journal of cardiovascular translational research · 2026

    Animal study (in vivo) · mouse · 9 results

  48. Nicotinamide Mononucleotide Attenuates Inflammatory Activation, Choroidal Neovascularization, and Lesion-Associated Remodeling.

    Wang J · Investigative ophthalmology & visual science · 2026

    Animal study (in vivo) · mouse · 13 results

  49. Enhancing the anti-ageing capacity of hUC-MSCs via NMN co-treatment in D-galactose-induced ageing mice and cellular senescence models.

    Liu K · Mechanisms of ageing and development · 2026

    Animal study (in vivo) · mouse · 15 results

  50. NMN alleviates oxidative stress damage in alopecia areata by activating SIRT7 and promoting glutamine metabolism.

    Cao T · Biochimica et biophysica acta. Gene regulatory mechanisms · 2026

    Animal study (in vivo) · mouse · 19 results

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