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NMN (nicotinamide mononucleotide) studies: 217 papers with results

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  1. CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves.

    Johnson S · NPJ aging and mechanisms of disease · 2018

    Animal study (in vivo) · mouse · 2 results

  2. Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury by modulating macrophage polarization via the SIRT1/NF-κB pathway.

    He S · Pharmaceutical biology · 2024

    Animal study (in vivo) · mouse · 12 results

  3. Nicotinamide mononucleotide attenuates isoproterenol-induced cardiac fibrosis by regulating oxidative stress and Smad3 acetylation.

    Wu K · Life sciences · 2021

    Animal study (in vivo) · mouse · 11 results

  4. Glycolysis-Mediated Activation of v-ATPase by Nicotinamide Mononucleotide Ameliorates Lipid-Induced Cardiomyopathy by Repressing the CD36-TLR4 Axis.

    Wang S · Circulation research · 2024

    Animal study (in vivo) · rat and mouse · 10 results

  5. Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models.

    Jiang Y · Cell discovery · 2022

    Animal study (in vivo) · mouse · 7 results

  6. Nicotinamide Mononucleotide Alleviates Cardiomyopathy Phenotypes Caused by Short-Chain Enoyl-Coa Hydratase 1 Deficiency.

    Cai K · JACC. Basic to translational science · 2022

    Animal study (in vivo) · mouse · 1 result

  7. Nicotinamide Mononucleotide Prevents Cisplatin-Induced Cognitive Impairments.

    Yoo KH · Cancer research · 2021

    Animal study (in vivo) · mouse · 6 results

  8. Nicotinamide Mononucleotide Ameliorates Sleep Deprivation-Induced Gut Microbiota Dysbiosis and Restores Colonization Resistance against Intestinal Infections.

    Fang D · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023

    Animal study (in vivo) · mouse · 4 results

  9. NAD+-boosting agent nicotinamide mononucleotide potently improves mitochondria stress response in Alzheimer's disease via ATF4-dependent mitochondrial UPR.

    Xiong X · Cell death & disease · 2024

    Animal study (in vivo) · mouse · 7 results

  10. Treatment of inflammatory bowel disease: Potential effect of NMN on intestinal barrier and gut microbiota.

    Huang P · Current research in food science · 2022

    Animal study (in vivo) · mouse · 11 results

  11. Improving lysosomal ferroptosis with NMN administration protects against heart failure.

    Yagi M · Life science alliance · 2023

    Animal study (in vivo) · mouse · 5 results

  12. Nicotinamide Mononucleotide Administration Restores Redox Homeostasis via the Sirt3-Nrf2 Axis and Protects Aged Mice from Oxidative Stress-Induced Liver Injury.

    Luo C · Journal of proteome research · 2022

    Animal study (in vivo) · mouse · 7 results

  13. Nicotinamide mononucleotide attenuates doxorubicin-induced cardiotoxicity by reducing oxidative stress, inflammation and apoptosis in rats.

    Wan Y · Archives of biochemistry and biophysics · 2021

    Animal study (in vivo) · rat · 11 results

  14. Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in mice.

    Youngson NA · Reproduction (Cambridge, England) · 2019

    Animal study (in vivo) · mouse · 9 results

  15. Monocyte-derived extracellular Nampt-dependent biosynthesis of NAD(+) protects the heart against pressure overload.

    Yano M · Scientific reports · 2015

    Animal study (in vivo) · mouse · 5 results

  16. Nicotinamide mononucleotide supplementation rescues mitochondrial and energy metabolism functions and ameliorates inflammatory states in the ovaries of aging mice.

    Liang J · MedComm · 2024

    Animal study (in vivo) · mouse · 11 results

  17. Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers.

    Uddin GM · Cells · 2020

    Animal study (in vivo) · mouse · 7 results

  18. β-Nicotinamide Mononucleotide (NMN) Administrated by Intraperitoneal Injection Mediates Protection Against UVB-Induced Skin Damage in Mice.

    Zhou X · Journal of inflammation research · 2021

    Animal study (in vivo) · mouse · 26 results

  19. Nicotinamide mononucleotide alleviates Aluminum induced bone loss by inhibiting the TXNIP-NLRP3 inflammasome.

    Liang H · Toxicology and applied pharmacology · 2019

    Animal study (in vivo) · rat · 8 results

  20. Nicotinamide Mononucleotide Attenuates LPS-Induced Acute Lung Injury With Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects.

    Tian Y · The Journal of surgical research · 2023

    Animal study (in vivo) · mouse · 12 results

  21. Nicotinamide Mononucleotide Administration Triggers Macrophages Reprogramming and Alleviates Inflammation During Sepsis Induced by Experimental Peritonitis.

    Cros C · Frontiers in molecular biosciences · 2022

    Animal study (in vivo) · mouse · 13 results

  22. Nicotinamide Mononucleotide Alleviates Osteoblast Senescence Induction and Promotes Bone Healing in Osteoporotic Mice.

    Lu Z · The journals of gerontology. Series A, Biological sciences and medical sciences · 2023

    Animal study (in vivo) · mouse · 14 results

  23. Nicotinamide Mononucleotide Administration Amends Protein Acetylome of Aged Mouse Liver.

    Luo C · Cells · 2022

    Animal study (in vivo) · mouse · 6 results

  24. Oral Administration of Nicotinamide Mononucleotide Increases Nicotinamide Adenine Dinucleotide Level in an Animal Brain.

    Ramanathan C · Nutrients · 2022

    Animal study (in vivo) · mouse · 1 result

  25. NAD+ supplementation prevents STING-induced senescence in CD8+ T cells by improving mitochondrial homeostasis.

    Ye B · Journal of cellular biochemistry · 2024

    Animal study (in vivo) · mouse · 7 results

  26. Nicotinamide mononucleotide improves the Alzheimer's disease by regulating intestinal microbiota.

    Zhao X · Biochemical and biophysical research communications · 2023

    Animal study (in vivo) · mouse · 3 results

  27. NMN alleviates radiation-induced intestinal fibrosis by modulating gut microbiota.

    Zhao X · International journal of radiation biology · 2023

    Animal study (in vivo) · mouse · 6 results

  28. Nicotinamide mononucleotide administration after sever hypoglycemia improves neuronal survival and cognitive function in rats.

    Wang X · Brain research bulletin · 2020

    Animal study (in vivo) · rat · 9 results

  29. Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease.

    Assiri MA · Human genomics · 2019

    Animal study (in vivo) · mouse · 7 results

  30. Nicotinamide mononucleotide ameliorates adriamycin-induced renal damage by epigenetically suppressing the NMN/NAD consumers mediated by Twist2.

    Hasegawa K · Scientific reports · 2022

    Animal study (in vivo) · mouse · 8 results

  31. Nicotinamide mononucleotide improves spermatogenic function in streptozotocin-induced diabetic mice via modulating the glycolysis pathway.

    Ma D · Acta biochimica et biophysica Sinica · 2022

    Animal study (in vivo) · mouse · 16 results

  32. Nicotinamide mononucleotide ameliorates senescence in alveolar epithelial cells.

    Fang T · MedComm · 2021

    Animal study (in vivo) · mouse · 3 results

  33. Nicotinamide Mononucleotide Prevents Retinal Dysfunction in a Mouse Model of Retinal Ischemia/Reperfusion Injury.

    Lee D · International journal of molecular sciences · 2022

    Animal study (in vivo) · mouse · 5 results

  34. Inhibition of nicotinamide phosphoribosyltransferase protects against acute pancreatitis via modulating macrophage polarization and its related metabolites.

    He Y · Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2021

    Animal study (in vivo) · mouse · 3 results

  35. Safety evaluation after acute and sub-chronic oral administration of high purity nicotinamide mononucleotide (NMN-C®) in Sprague-Dawley rats.

    Cros C · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2021

    Animal study (in vivo) · sprague-dawley rats · 12 results

  36. Assessing the Effects of Nicotinamide Mononucleotide Supplementation on Pulmonary Inflammation in Male Mice Subchronically Exposed to Ambient Particulate Matter.

    Zhang R · Environmental health perspectives · 2023

    Animal study (in vivo) · mouse · 12 results

  37. Nicotinamide mononucleotide ameliorates DNFB-induced atopic dermatitis-like symptoms in mice by blocking activation of ROS-mediated JAK2/STAT5 signaling pathway.

    Gao JF · International immunopharmacology · 2022

    Animal study (in vivo) · mouse · 6 results

  38. Nicotinamide Mononucleotide Ameliorates Silica-Induced Lung Injury through the Nrf2-Regulated Glutathione Metabolism Pathway in Mice.

    Wang L · Nutrients · 2022

    Animal study (in vivo) · mouse · 15 results

  39. Nicotinamide Mononucleotide Administration Prevents Doxorubicin-Induced Cardiotoxicity and Loss in Physical Activity in Mice.

    Margier M · Cells · 2022

    Animal study (in vivo) · mouse · 12 results

  40. Nicotinamide mononucleotide protects septic hearts in mice via preventing cyclophilin F modification and lysosomal dysfunction.

    Ni R · Acta pharmacologica Sinica · 2025

    Animal study (in vivo) · mouse · 15 results

  41. Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high-fat diet.

    Zhang Y · IUBMB life · 2023

    Animal study (in vivo) · mouse · 7 results

  42. NMN reverses D-galactose-induced neurodegeneration and enhances the intestinal barrier of mice by activating the Sirt1 pathway.

    Lin Y · Frontiers in pharmacology · 2025

    Animal study (in vivo) · mouse · 20 results

  43. Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome.

    Ho WJ · EMBO molecular medicine · 2024

    Animal study (in vivo) · mouse · 6 results

  44. The Role of Nicotinamide Mononucleotide Supplementation in Psoriasis Treatment.

    Zhang Z · Antioxidants (Basel, Switzerland) · 2024

    Animal study (in vivo) · mouse · 13 results

  45. Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma.

    Liang J · International immunopharmacology · 2024

    Animal study (in vivo) · mouse · 6 results

  46. Nicotinamide mononucleotide attenuates HIF-1α activation and fibrosis in hypoxic adipose tissue via NAD+/SIRT1 axis.

    Wu K · Frontiers in endocrinology · 2023

    Animal study (in vivo) · mouse · 9 results

  47. Nicotinamide Mononucleotide Protects against Retinal Dysfunction in a Murine Model of Carotid Artery Occlusion.

    Lee D · International journal of molecular sciences · 2022

    Animal study (in vivo) · mouse · 4 results

  48. NMN Supplementation Inhibits Endothelial Cell ROS-Mediated Src/Pi3k/Akt Signaling Pathway to Protect High-Altitude Blood-Retinal Barrier.

    Liu S · Investigative ophthalmology & visual science · 2025

    Animal study (in vivo) · mouse · 7 results

  49. Nicotinamide mononucleotide alleviates seizures via modulating SIRT1-PGC-1α mediated mitochondrial fusion and fission.

    Cheng Y · Journal of neurochemistry · 2024

    Animal study (in vivo) · mouse · 16 results

  50. Quantitative Acetylomics Reveals Dynamics of Protein Lysine Acetylation in Mouse Livers During Aging and Upon the Treatment of Nicotinamide Mononucleotide.

    Li J · Molecular & cellular proteomics : MCP · 2022

    Animal study (in vivo) · mouse · 2 results

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