In uranium-exposed mice, NMN improved testicular function compared with saline treatment.
In plain wordsIn mice exposed to uranium, NMN improved testicular function compared with saline.
- Outcome
- IncreaseTesticular function
- Study
mousen: not reported in source
uranium-exposed mice- Comparator
- saline-treated uranium-exposed mice
- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
- Studied dose
- 500 mg/kg · oralAs given in this study (mouse).
Source sentences
NMN treatment resulted in a significant enhancement of testicular function compared with saline-treated uranium-exposed mice.
2 context sentences(design, population, supporting numbers)
To this end, a research model was established in which testicular damage and spermatogenic dysfunction were induced in adult male mice by intraperitoneal injection of 2 different doses of uranyl nitrate.
Following a week of intraperitoneal injection, the mice were given oral doses of 500 mg/kg of NMN.