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NMN (nicotinamide mononucleotide) studies: 217 papers with results

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  1. Investigating the effects of nicotinamide mononucleotide administration on testicular apoptosis, and mitochondrial function in doxorubicin-treated rats.

    Yousefi Khiabani P · Molecular biology reports · 2026

    Animal study (in vivo) · rat · 9 results

  2. Elamipretide (SS-31) and Nicotinamide Mononucleotide (NMN) Combination Therapy Targets TREM2 to Mitigate Post-ischemic Brain Injury in Mice.

    Yang Q · Neurochemical research · 2026

    Animal study (in vivo) · mouse · 23 results

  3. Sleep-wake and circadian behavior in brain-specific sirtuin 1 knockout mice and effects of nicotinamide mononucleotide supplementation.

    Sakai N · Scientific reports · 2026

    Animal study (in vivo) · mouse · 4 results

  4. Nicotinamide Mononucleotide Ameliorates Nano-Aluminum Oxide-Induced Cognitive Impairment and Ferroptosis via the GSH/GPX4 Axis.

    Yu L · Small (Weinheim an der Bergstrasse, Germany) · 2026

    Animal study (in vivo) · mouse · 12 results

  5. Nicotinamide mononucleotide supplementation modulates gut microbiota and metabolites to mitigate Alzheimer's disease pathology in APP/PS1 mice.

    Zhou H · Journal of Alzheimer's disease : JAD · 2026

    Animal study (in vivo) · mouse · 14 results

  6. Nicotinamide mononucleotide attenuates hyperandrogenism in a polycystic ovary syndrome-like rat model by suppressing NLRP3 inflammasome-mediated granulosa-cell pyroptosis.

    Zhang Y · Journal of ovarian research · 2026

    Animal study (in vivo) · rat · 13 results

  7. Nicotinamide Mononucleotide Improves High-Fat Diet-Induced Myocardial Damage of Aging Mice through the Sirt3/PINK1/Parkin Signaling Pathway.

    Wen X · The Journal of nutrition · 2026

    Animal study (in vivo) · mouse · 24 results

  8. NMN prevents obesity-induced osteoporosis by promoting mitophagy to restore type H vessels.

    Shen M · Biochemical pharmacology · 2026

    Animal study (in vivo) · mouse · 11 results

  9. β-Nicotinamide Mononucleotide protects against endotoxemia-induced myocardial injury through Sirt5-dependent desuccinylation of succinate dehydrogenase.

    Tao H · European journal of pharmacology · 2026

    Animal study (in vivo) · mouse · 16 results

  10. Beta-nicotinamide mononucleotide attenuates creatine kinase release in Duchenne muscular dystrophy model rats.

    Nakamura K · The Journal of veterinary medical science · 2026

    Animal study (in vivo) · rat · 3 results

  11. Nicotinamide Mononucleotide Alleviates the Development of Fibrotic Cataract by Modulating the Nrf2/FPN1 Signaling Pathway.

    Bao X · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025

    Animal study (in vivo) · mouse · 14 results

  12. NAD + -Boosting Ameliorates Heme Protein-Mediated Acute Kidney Injury.

    Singh RD · Kidney360 · 2026

    Animal study (in vivo) · mouse · 15 results

  13. Beta-Hydroxybutyrate but not NMN supplementation mimics caloric restriction reducing early mortality in Daphnia.

    Pearson AC · Biogerontology · 2025

    Animal study (in vivo) · daphnia · 6 results

  14. Nicotinamide mononucleotide attenuates hepatic endoplasmic reticulum stress and modulates circadian rhythms in young mice with diet-induced obesity.

    Kwon SY · Nutrition research and practice · 2026

    Animal study (in vivo) · mouse · 5 results

  15. [Caffeoylquinic acids from Erigeron breviscapus ameliorates cognitive impairment and mitochondrial dysfunction in AD by activating PINK1/Parkin-mediated mitophagy].

    Pu YZ · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica · 2025

    Animal study (in vivo) · rat · 13 results

  16. Single bolus injection of nicotinamide mono nucleotide increases systemic insulin sensitivity in association with activation of NAD salvage pathway in the liver and adipose tissue in mice.

    Hiroshige S · Endocrine journal · 2025

    Animal study (in vivo) · mouse · 7 results

  17. Acute Nicotinamide Adenine Dinucleotide Supplementation via Nicotinamide Mononucleotide Does Not Rescue Functional Impairment in a Lipopolysaccharide-induced Delirium Mouse Model.

    Chui MKK · The journals of gerontology. Series A, Biological sciences and medical sciences · 2025

    Animal study (in vivo) · mouse · 3 results

  18. Nicotinamide mononucleotide restores oxidative stress-related apoptosis of oocyte exposed to benzyl butyl phthalate in mice.

    Jiang Y · Cell proliferation · 2023

    Other design · mouse · 1 result

  19. Deacetylation of SRF catalyzed by SIRT7 protects against abdominal aortic aneurysm formation.

    Xiong Y · Experimental & molecular medicine · 2026

    Other design · 1 result

  20. Suppression of leukocyte infiltration and cartilage degradation by selective inhibition of pre-B cell colony-enhancing factor/visfatin/nicotinamide phosphoribosyltransferase: Apo866-mediated therapy in human fibroblasts and murine collagen-induced arthritis.

    Evans L · Arthritis and rheumatism · 2011

    Ex vivo tissue · mouse · 2 results

  21. Oxidative degradation of dihydrofolate reductase increases CD38-mediated ferroptosis susceptibility.

    Ma Y · Cell death & disease · 2022

    Ex vivo tissue · mouse · 2 results

  22. Nicotinamide Mononucleotide improves oocyte maturation of mice with type 1 diabetes.

    Guo F · Nutrition & diabetes · 2024

    Ex vivo tissue · mouse · 7 results

  23. Nicotinamide mononucleotide restores impaired metabolism, endothelial cell proliferation and angiogenesis in old sedentary male mice.

    Kiesworo K · iScience · 2025

    Ex vivo tissue · mouse · 2 results

  24. Reverse Effects of Nicotinamide Mononucleotide Supplementation on Declining Quality of Oocytes With Polycystic Ovary Syndrome.

    Fan Y · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025

    Ex vivo tissue · mouse · 6 results

  25. Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.

    Kiss T · GeroScience · 2019

    In vitro (cells) · rat · 3 results

  26. Cardiomyocyte Sirt (Sirtuin) 7 Ameliorates Stress-Induced Cardiac Hypertrophy by Interacting With and Deacetylating GATA4.

    Yamamura S · Hypertension (Dallas, Tex. : 1979) · 2020

    In vitro (cells) · 1 result

  27. Improving retinal mitochondrial function as a treatment for age-related macular degeneration.

    Ebeling MC · Redox biology · 2020

    In vitro (cells) · 6 results

  28. Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress via Decreasing COX-2 Expression in Macrophages.

    Liu J · Frontiers in molecular biosciences · 2021

    In vitro (cells) · 6 results

  29. Nicotinamide mononucleotide increases cell viability and restores tight junctions in high-glucose-treated human corneal epithelial cells via the SIRT1/Nrf2/HO-1 pathway.

    Pu Q · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022

    In vitro (cells) · 6 results

  30. Nicotinamide Mononucleotide Restores NAD+ Levels to Alleviate LPS-Induced Inflammation via the TLR4/NF-κB/MAPK Signaling Pathway in Mice Granulosa Cells.

    Ahmed M · Antioxidants (Basel, Switzerland) · 2024

    In vitro (cells) · mouse · 17 results

  31. Niacin receptor activation improves human microvascular endothelial cell angiogenic function during lipotoxicity.

    Hughes-Large JM · Atherosclerosis · 2014

    In vitro (cells) · 3 results

  32. Nicotinamide mononucleotide supplementation improves the quality of porcine oocytes under heat stress.

    Song M · Journal of animal science and biotechnology · 2022

    In vitro (cells) · pig · 2 results

  33. Resveratrol attenuates excessive ethanol exposure-induced β-cell senescence in rats: A critical role for the NAD+/SIRT1-p38MAPK/p16 pathway.

    Luo G · The Journal of nutritional biochemistry · 2021

    In vitro (cells) · 1 result

  34. Resveratrol protects against ethanol-induced impairment of insulin secretion in INS-1 cells through SIRT1-UCP2 axis.

    Luo G · Toxicology in vitro : an international journal published in association with BIBRA · 2020

    In vitro (cells) · rat · 2 results

  35. Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells.

    Penke M · Lipids in health and disease · 2017

    In vitro (cells) · 2 results

  36. Nicotinamide Mononucleotide Restores the Meiotic Competency of Porcine Oocytes Exposed to Ethylene Glycol Butyl Ether.

    Miao Y · Frontiers in cell and developmental biology · 2021

    In vitro (cells) · pig · 4 results

  37. Nicotinamide Mononucleotide and Coenzyme Q10 Protects Fibroblast Senescence Induced by Particulate Matter Preconditioned Mast Cells.

    Chang TM · International journal of molecular sciences · 2022

    In vitro (cells) · 6 results

  38. β-nicotinamide mononucleotide rescues the quality of aged oocyte and improves subsequent embryo development in pigs.

    Li L · PloS one · 2023

    In vitro (cells) · pig · 9 results

  39. Nicotinamide Mononucleotide Prevents Cisplatin-Induced Mitochondrial Defects in Cortical Neurons Derived from Human Induced Pluripotent Stem Cells.

    Rashid MA · Brain plasticity (Amsterdam, Netherlands) · 2022

    In vitro (cells) · 1 result

  40. Nicotinamide Mononucleotide (NMN) Ameliorates Free Fatty Acid-Induced Pancreatic β-Cell Dysfunction via the NAD+/AMPK/SIRT1/HIF-1α Pathway.

    Wang Y · International journal of molecular sciences · 2024

    In vitro (cells) · 2 results

  41. β-Nicotinamide Mononucleotide Alleviates Hydrogen Peroxide-Induced Cell Cycle Arrest and Death in Ovarian Granulosa Cells.

    Wang Y · International journal of molecular sciences · 2023

    In vitro (cells) · mouse · 7 results

  42. Nicotinamide mononucleotide (NMN) alleviates the poly(I:C)-induced inflammatory response in human primary cell cultures.

    Sano H · Scientific reports · 2023

    In vitro (cells) · 4 results

  43. SIRT1 Prevents Lens Epithelial Cell Senescence During Age-Related Cataract via Regulating p66Shc.

    Liu H · Aging cell · 2025

    In vitro (cells) · 4 results

  44. Nicotinamide Mononucleotide (NMN) Improves the Senescence of Mouse Vascular Smooth Muscle Cells Induced by Ang II Through Activating p-AMPK/KLF4 Pathway.

    Liang N · Pharmaceuticals (Basel, Switzerland) · 2025

    In vitro (cells) · mouse · 9 results

  45. Histidine triad nucleotide-binding protein 2 attenuates doxorubicin-induced cardiotoxicity through restoring lysosomal function and promoting autophagy in mice.

    Jiang H · MedComm · 2025

    In vitro (cells) · 1 result

  46. Nicotinamide Adenine Dinucleotide Precursor Supplementation Modulates Neurite Complexity and Survival in Motor Neurons from Amyotrophic Lateral Sclerosis Models.

    Hamilton HL · Antioxidants & redox signaling · 2024

    In vitro (cells) · mouse · 7 results

  47. Nicotinamide Mononucleotide Alleviates Angiotensin II-Induced Human Aortic Smooth Muscle Cell Senescence in a Microphysiological Model.

    Yin X · Journal of cardiovascular pharmacology · 2023

    In vitro (cells) · 3 results

  48. Nicotinamide Ameliorates Deoxynivalenol-Induced Injury in Renal Cells via Inhibiting PARP1 Hyperactivation and Restoring NAD+ Homeostasis.

    Chen C · Toxins · 2026

    In vitro (cells) · 1 result

  49. DMPC-Based Liposomal Vesicles for Encapsulation and Controlled Release of NMN and Matrigel in Sarcopenia Therapy.

    Najm A · International journal of molecular sciences · 2025

    In vitro (cells) · 7 results

  50. NMN protects vascular endothelial cells from M1 macrophage-derived IL-1β-induced hyperpermeability by inhibiting VE-cadherin degradation.

    Katayoshi T · Frontiers in cardiovascular medicine · 2026

    In vitro (cells) · 7 results

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