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Study · Animal study (in vivo) · mouse · 2025

3 results

Bazi Bushen capsule alleviates skin photoaging by targeting the KEAP1-NRF2 pathway.

Jiang Y, Li M, Li H, Li Y, Guo Z, Xing X, Niu K, Zhang R, Lu X, Zhao Z, Zhou L, Kang T, Hou Y, Wu Y

Phytomedicine : international journal of phytotherapy and phytopharmacology3 Oct 2025Cited by 6 (Europe PMC)

PMID41101077 (opens in a new tab)DOI10.1016/j.phymed.2025.157360 (opens in a new tab)PepBankPUB-41101077
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In photoaged mice, NMN mitigated UVR-induced structural and functional degeneration.

    In plain wordsIn mice, NMN reduced structural and functional damage caused by ultraviolet radiation.

    Peptide
    NMN (nicotinamide mononucleotide)
    Outcome
    DecreaseStructural and functional degeneration
    Study

    mousen: not reported in source

    UVR-induced photoaging
    Outcome group
    Skin and hair · Skin and wound
    Studied dose
    Dose not stated

    Source sentences

    Summary
    BZBS and β-Nicotinamide Mononucleotide (NMN) effectively mitigated structural and functional degeneration caused by ultraviolet radiation (UVR) of the mice, promoted hair follicle growth, and suppressed inflammatory cell infiltration.
    1 context sentence
    Summary · context
    Laser Doppler flow imaging, histopathological examination, biochemical evaluation, western blot (WB), real-time reverse transcription-polymerase chain reaction (RT-qPCR) and immunofluorescence staining were employed to evaluate the therapeutic effects of BZBS in photoaging mice.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In photoaged mice, NMN promoted hair follicle growth.

    In plain wordsIn mice with ultraviolet damage, NMN increased hair follicle growth.

    Peptide
    NMN (nicotinamide mononucleotide)
    Outcome
    IncreaseHair follicle growth
    Study

    mousen: not reported in source

    UVR-induced photoaging
    Outcome group
    Skin and hair · Skin and wound
    Studied dose
    Dose not stated

    Source sentences

    Summary
    BZBS and β-Nicotinamide Mononucleotide (NMN) effectively mitigated structural and functional degeneration caused by ultraviolet radiation (UVR) of the mice, promoted hair follicle growth, and suppressed inflammatory cell infiltration.
    1 context sentence
    Summary · context
    Laser Doppler flow imaging, histopathological examination, biochemical evaluation, western blot (WB), real-time reverse transcription-polymerase chain reaction (RT-qPCR) and immunofluorescence staining were employed to evaluate the therapeutic effects of BZBS in photoaging mice.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In photoaged mice, NMN suppressed inflammatory cell infiltration.

    In plain wordsIn mice with ultraviolet damage, NMN reduced inflammatory cell infiltration.

    Peptide
    NMN (nicotinamide mononucleotide)
    Outcome
    DecreaseInflammatory cell infiltration
    Study

    mousen: not reported in source

    UVR-induced photoaging
    Outcome group
    Inflammation markers · Skin and wound
    Studied dose
    Dose not stated

    Source sentences

    Summary
    BZBS and β-Nicotinamide Mononucleotide (NMN) effectively mitigated structural and functional degeneration caused by ultraviolet radiation (UVR) of the mice, promoted hair follicle growth, and suppressed inflammatory cell infiltration.
    1 context sentence
    Summary · context
    Laser Doppler flow imaging, histopathological examination, biochemical evaluation, western blot (WB), real-time reverse transcription-polymerase chain reaction (RT-qPCR) and immunofluorescence staining were employed to evaluate the therapeutic effects of BZBS in photoaging mice.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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