Study · Animal study (in vivo) · mouse · 2024
17 resultsGu Y, Gao L, He J, Luo M, Hu M, Lin Y, Li J, Hou T, Si J, Yu Y
Food & function18 Mar 2024Cited by 9 (Europe PMC)
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Text rights: CC BY-NC. Results still quote short attributed sentences.
17 results from studies that gave the peptide. No result from this study comes from people.
In prematurely aged Zmpste24-deficient mice, NMN prolonged lifespan.
In plain wordsIn mice with premature aging, NMN prolonged lifespan.
mousen: not reported in source
Zmpste24-deficient prematurely aged miceSource sentences
In our research, Zmpste24-/- mice proved that NMN prolonged their life span and delayed senescence.
In prematurely aged mice, NMN delayed senescence.
In plain wordsIn mice with premature aging, NMN delayed senescence.
mousen: not reported in source
Zmpste24-deficient prematurely aged miceSource sentences
In our research, Zmpste24-/- mice proved that NMN prolonged their life span and delayed senescence.
In aging mice, NMN improved intestinal epithelial pathology.
In plain wordsIn mice, NMN improved damage in intestinal lining cells.
mousen: not reported in source
aging miceSource sentences
Our results indicated that NMN improved the pathology of intestinal epithelial cells and intestinal permeability by upregulating the expression of intestinal tight junction proteins and the number of goblet cells, increasing the release of anti-inflammatory factors, and increasing beneficial intestinal bacteria.
In aging mice, NMN improved intestinal permeability.
In plain wordsIn mice, NMN improved intestinal permeability.
mousen: not reported in source
aging miceSource sentences
Our results indicated that NMN improved the pathology of intestinal epithelial cells and intestinal permeability by upregulating the expression of intestinal tight junction proteins and the number of goblet cells, increasing the release of anti-inflammatory factors, and increasing beneficial intestinal bacteria.
In aging mice, NMN increased intestinal tight junction protein expression.
In plain wordsIn mice, NMN increased intestinal tight junction proteins.
mousen: not reported in source
aging miceSource sentences
Our results indicated that NMN improved the pathology of intestinal epithelial cells and intestinal permeability by upregulating the expression of intestinal tight junction proteins and the number of goblet cells, increasing the release of anti-inflammatory factors, and increasing beneficial intestinal bacteria.
In aging mice, NMN increased goblet cell numbers.
In plain wordsIn mice, NMN increased intestinal goblet cell numbers.
mousen: not reported in source
aging miceSource sentences
Our results indicated that NMN improved the pathology of intestinal epithelial cells and intestinal permeability by upregulating the expression of intestinal tight junction proteins and the number of goblet cells, increasing the release of anti-inflammatory factors, and increasing beneficial intestinal bacteria.
In aging mice, NMN increased anti-inflammatory factor release.
In plain wordsIn mice, NMN increased the release of anti-inflammatory factors.
mousen: not reported in source
aging miceSource sentences
Our results indicated that NMN improved the pathology of intestinal epithelial cells and intestinal permeability by upregulating the expression of intestinal tight junction proteins and the number of goblet cells, increasing the release of anti-inflammatory factors, and increasing beneficial intestinal bacteria.
In aging mice, NMN increased beneficial intestinal bacteria.
In plain wordsIn mice, NMN increased beneficial intestinal bacteria.
mousen: not reported in source
aging miceSource sentences
Our results indicated that NMN improved the pathology of intestinal epithelial cells and intestinal permeability by upregulating the expression of intestinal tight junction proteins and the number of goblet cells, increasing the release of anti-inflammatory factors, and increasing beneficial intestinal bacteria.
In aging mice, NMN increased SIRT1 protein expression.
In plain wordsIn mice, NMN increased SIRT1 protein levels.
mousen: not reported in source
aging miceSource sentences
NMN increased the expression of the proteins SIRT1, NMNAT2, and NMNAT3 and decreased the expression of the protein P53.
In aging mice, NMN increased NMNAT2 protein expression.
In plain wordsIn mice, NMN increased NMNAT2 protein levels.
mousen: not reported in source
aging miceSource sentences
NMN increased the expression of the proteins SIRT1, NMNAT2, and NMNAT3 and decreased the expression of the protein P53.
In aging mice, NMN increased NMNAT3 protein expression.
In plain wordsIn mice, NMN increased NMNAT3 protein levels.
mousen: not reported in source
aging miceSource sentences
NMN increased the expression of the proteins SIRT1, NMNAT2, and NMNAT3 and decreased the expression of the protein P53.
In aging mice, NMN decreased P53 protein expression.
In plain wordsIn mice, NMN reduced P53 protein levels.
mousen: not reported in source
aging miceSource sentences
NMN increased the expression of the proteins SIRT1, NMNAT2, and NMNAT3 and decreased the expression of the protein P53.
In aging mice, NMN increased Wnt/β-catenin signaling associated with intestinal stem cell regulation.
In plain wordsIn mice, NMN increased Wnt/β-catenin signaling in intestinal stem cell regulation.
mousen: not reported in source
aging miceSource sentences
It also regulated the activity of ISCs by increasing Wnt/β-catenin and Lgr5.
In aging mice, NMN increased Lgr5.
In plain wordsIn mice, NMN increased Lgr5.
mousen: not reported in source
aging miceSource sentences
It also regulated the activity of ISCs by increasing Wnt/β-catenin and Lgr5.
In aging mice, NMN increased relative Akkermansia muciniphila abundance.
In plain wordsIn mice, NMN increased the relative abundance of Akkermansia muciniphila.
mousen: not reported in source
aging miceSource sentences
Our findings also revealed that NMN caused a significant increase in the relative abundance of Akkermansia muciniphila and Bifidobacterium pseudolongum and notable differences in metabolic pathways related to choline metabolism in cancer.
In aging mice, NMN increased relative Bifidobacterium pseudolongum abundance.
In plain wordsIn mice, NMN increased the relative abundance of Bifidobacterium pseudolongum.
mousen: not reported in source
aging miceSource sentences
Our findings also revealed that NMN caused a significant increase in the relative abundance of Akkermansia muciniphila and Bifidobacterium pseudolongum and notable differences in metabolic pathways related to choline metabolism in cancer.
In aging mice, NMN altered pathways related to choline metabolism in cancer.
In plain wordsIn mice, NMN altered pathways related to choline metabolism in cancer.
mousen: not reported in source
aging miceSource sentences
Our findings also revealed that NMN caused a significant increase in the relative abundance of Akkermansia muciniphila and Bifidobacterium pseudolongum and notable differences in metabolic pathways related to choline metabolism in cancer.
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Version 2Current
21 Oct 2026, 15:58 UTC
Study results updated
Version 1
21 Oct 2026, 12:50 UTC
First added · source update from Europe PMC
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In PepBank now:147 peptides, 6 blends and 13 other compounds97,577 study results from 17,383 studies8,473 clinical trialsUpdated