Melanotan II studies: 324 papers with results
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- Melanocortin-4 receptor activation inhibits c-Jun N-terminal kinase activity and promotes insulin signaling.
Chai B · Peptides · 2009
Animal study (in vivo) · rat · 1 result
- Interrelationships between mu opioid and melanocortin receptors in mediating food intake in rats.
Grossman HC · Brain research · 2003
Animal study (in vivo) · rat · 1 result
- MC-3 receptor and the inflammatory mechanisms activated in acute myocardial infarct.
Getting SJ · Journal of leukocyte biology · 2004
Animal study (in vivo) · mouse · 8 results
- CNS melanocortin and leptin effects on stearoyl-CoA desaturase-1 and resistin expression.
Lin J · Biochemical and biophysical research communications · 2003
Animal study (in vivo) · rat · 3 results
- Central melanocortin stimulation increases phosphorylated perilipin A and hormone-sensitive lipase in adipose tissues.
Shrestha YB · American journal of physiology. Regulatory, integrative and comparative physiology · 2010
Animal study (in vivo) · siberian hamster · 5 results
- Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice.
Heijboer AC · Diabetologia · 2005
Animal study (in vivo) · mouse · 7 results
- Biphasic effect of melanocortin agonists on metabolic rate and body temperature.
Lute B · Cell metabolism · 2014
Animal study (in vivo) · mouse · 4 results
- Chronic infusion of a melanocortin receptor agonist modulates dopamine receptor binding in the rat brain.
Lindblom J · Pharmacological research · 2002
Animal study (in vivo) · rat · 4 results
- Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides.
Getting SJ · The Journal of pharmacology and experimental therapeutics · 2003
Animal study (in vivo) · mouse · 11 results
- High-fat intake induced by mu-opioid activation of the nucleus accumbens is inhibited by Y1R-blockade and MC3/4R- stimulation.
Zheng H · Brain research · 2010
Animal study (in vivo) · rat · 2 results
- Decreased consumption of rewarding sucrose solutions after injection of melanocortins into the ventral tegmental area of rats.
Yen HH · Psychopharmacology · 2015
Animal study (in vivo) · rat · 5 results
- Assessment of voluntary ethanol consumption and the effects of a melanocortin (MC) receptor agonist on ethanol intake in mutant C57BL/6J mice lacking the MC-4 receptor.
Navarro M · Alcoholism, clinical and experimental research · 2011
Animal study (in vivo) · mouse · 7 results
- The melanocortin circuit in obese and lean strains of chicks.
Hen G · The Journal of endocrinology · 2006
Animal study (in vivo) · chicken · 2 results
- Feeding response to melanocortin agonist predicts preference for and obesity from a high-fat diet.
Chandler PC · Physiology & behavior · 2005
Animal study (in vivo) · rat · 4 results
- Melanocortinergic activation by melanotan II inhibits feeding and increases uncoupling protein 1 messenger ribonucleic acid in the developing rat.
Glavas MM · Endocrinology · 2007
Animal study (in vivo) · rat · 5 results
- Chronic blockade of melanocortin receptors alleviates allodynia in rats with neuropathic pain.
Vrinten DH · Anesthesia and analgesia · 2001
Animal study (in vivo) · rat · 1 result
- Gonadotropin-releasing hormone II (GnRH II) mediates the anorexigenic actions of α-melanocyte-stimulating hormone (α-MSH) and corticotropin-releasing hormone (CRH) in goldfish.
Kang KS · Peptides · 2011
Animal study (in vivo) · goldfish · 3 results
- Amygdalar opioids modulate hypothalamic melanocortin-induced anorexia.
Beckman TR · Physiology & behavior · 2009
Animal study (in vivo) · rat · 4 results
- Feeding responses to a melanocortin agonist and antagonist in obesity induced by a palatable high-fat diet.
Hansen MJ · Brain research · 2005
Animal study (in vivo) · rat · 3 results
- Melanocortin receptors mediate the excitatory effects of blood-borne murine leptin on hypothalamic paraventricular neurons in rat.
Zhang ZH · American journal of physiology. Regulatory, integrative and comparative physiology · 2004
Animal study (in vivo) · rat · 5 results
- Neonatal melanocortin receptor agonist treatment reduces play fighting and promotes adult attachment in prairie voles in a sex-dependent manner.
Barrett CE · Neuropharmacology · 2014
Animal study (in vivo) · prairie vole · 4 results
- Hypothalamic POMC deficiency increases circulating adiponectin despite obesity.
Yu H · Molecular metabolism · 2020
Animal study (in vivo) · mouse · 1 result
- Pain reduces sexual motivation in female but not male mice.
Farmer MA · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
Animal study (in vivo) · mouse · 1 result
- Melanocortin signaling in the brainstem influences vagal outflow to the stomach.
Richardson J · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
Animal study (in vivo) · rat · 6 results
- The medial preoptic nucleus as a site of the thermogenic and metabolic actions of melanotan II in male rats.
Monge-Roffarello B · American journal of physiology. Regulatory, integrative and comparative physiology · 2014
Animal study (in vivo) · rat · 9 results
- Altered feeding and body weight following melanocortin administration to the ventral tegmental area in adult rats.
Roseberry AG · Psychopharmacology · 2013
Animal study (in vivo) · rat · 1 result
- Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency.
De Jonghe BC · American journal of physiology. Endocrinology and metabolism · 2012
Animal study (in vivo) · mouse · 4 results
- Evaluation of the lack of anorectic effect of intracerebroventricular insulin in rats.
Jessen L · American journal of physiology. Regulatory, integrative and comparative physiology · 2010
Animal study (in vivo) · rat · 2 results
- Gastrin-releasing peptide messenger ribonucleic acid expression in the hypothalamic paraventricular nucleus is altered by melanocortin receptor stimulation and food deprivation.
Ladenheim EE · Endocrinology · 2009
Animal study (in vivo) · rat · 2 results
- MTII attenuates ghrelin- and food deprivation-induced increases in food hoarding and food intake.
Keen-Rhinehart E · Hormones and behavior · 2007
Animal study (in vivo) · siberian hamster · 4 results
- Pharmacological activation of the melanocortin system limits plaque inflammation and ameliorates vascular dysfunction in atherosclerotic mice.
Rinne P · Arteriosclerosis, thrombosis, and vascular biology · 2014
Animal study (in vivo) · mouse · 10 results
- The anorectic effect of GLP-1 in rats is nutrient dependent.
Sandoval D · PloS one · 2012
Animal study (in vivo) · rat · 1 result
- Alterations in activity and energy expenditure contribute to lean phenotype in Fischer 344 rats lacking the cholecystokinin-1 receptor gene.
Blevins JE · American journal of physiology. Regulatory, integrative and comparative physiology · 2012
Animal study (in vivo) · rat · 2 results
- Relationship between alpha-melanocyte-stimulating hormone- and neuropeptide Y-containing neurons in the goldfish hypothalamus.
Kojima K · General and comparative endocrinology · 2010
Animal study (in vivo) · goldfish · 1 result
- Role of hypothalamic interleukin-1beta (IL-1beta) in regulation of energy homeostasis by melanocortins.
Wisse BE · Peptides · 2006
Animal study (in vivo) · 3 results
- The effect of the melanocortin agonist, MT-II, on the defended level of body adiposity.
Seeley RJ · Endocrinology · 2005
Animal study (in vivo) · rat · 2 results
- Melanocortin receptors mediate leptin effects on feeding and body weight but not adipose apoptosis.
Choi YH · Physiology & behavior · 2003
Animal study (in vivo) · rat · 5 results
- Melanocortin receptor agonist transiently increases oxygen consumption in rats.
Jonsson L · Neuroreport · 2001
Animal study (in vivo) · rat · 4 results
- Central vagal afferent endings mediate reduction of food intake by melanocortin-3/4 receptor agonist.
Campos CA · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
Animal study (in vivo) · rat · 6 results
- Central administration of melanocortin agonist increased insulin sensitivity in diet-induced obese rats.
Banno R · FEBS letters · 2007
Animal study (in vivo) · rat · 5 results
- MT-II induces penile erection via brain and spinal mechanisms.
Wessells H · Annals of the New York Academy of Sciences · 2003
Animal study (in vivo) · rat · 5 results
- Role of MC4 receptors in the depressor and bradycardic effects of alpha-MSH in the nucleus tractus solitarii of the rat.
Pavia JM · Neuroreport · 2003
Animal study (in vivo) · rat · 3 results
- Sites and sources of sympathoexcitation in obese male rats: role of brain insulin.
Shi Z · American journal of physiology. Regulatory, integrative and comparative physiology · 2020
Animal study (in vivo) · rat · 1 result
- Lateral hypothalamic melanocortin receptor signaling modulates binge-like ethanol drinking in C57BL/6J mice.
Sprow GM · Addiction biology · 2016
Animal study (in vivo) · mouse · 1 result
- Role of melanocortin signaling in neuroendocrine and metabolic actions of leptin in male rats with uncontrolled diabetes.
Meek TH · Endocrinology · 2014
Animal study (in vivo) · rat · 2 results
- Anxiolytic-like effect of a selective and non-peptidergic melanocortin 4 receptor antagonist, MCL0129, in a social interaction test.
Shimazaki T · Pharmacology, biochemistry, and behavior · 2005
Animal study (in vivo) · 1 result
- Melanocortin receptor agonists and antagonists modulate nociceptive sensitivity in the mouse formalin test.
Bellasio S · European journal of pharmacology · 2003
Animal study (in vivo) · mouse · 1 result
- Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII.
Benoit SC · Diabetes · 2003
Animal study (in vivo) · rat · 3 results
- Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice.
Tooke BP · Molecular metabolism · 2019
Animal study (in vivo) · mouse · 1 result
- The anorexigenic action of the octadecaneuropeptide (ODN) in goldfish is mediated through the MC4R- and subsequently the CRH receptor-signaling pathways.
Matsuda K · Journal of molecular neuroscience : MN · 2010
Animal study (in vivo) · goldfish · 1 result