In female mice with inflammatory pain, melanotan II rescued the pain-induced reduction in sexual behavior.
In plain wordsIn female mice with pain, melanotan II restored the sexual behavior that pain had reduced.
- Peptide
- Melanotan II
- Outcome
- IncreaseRescue of pain-induced reduction in female sexual behavior
- Study
mousen: not reported in source
- Outcome group
- Sexual function · Reproductive and sexual health
- Studied dose
- Dose not stated
Source sentences
Pain-induced reductions in female sexual behavior were observed in the absence of sex differences in pain-related behavior, and could be rescued by the analgesic, pregabalin, and the libido-enhancing drugs, apomorphine and melanotan-II.
1 context sentence(design, population, supporting numbers)
We find that inflammatory pain reduces sexual motivation, measured via mounting behavior and/or proximity in a paced mating paradigm, in female but not male laboratory mice.