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Study · Animal study (in vivo) · goldfish · 2010

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The anorexigenic action of the octadecaneuropeptide (ODN) in goldfish is mediated through the MC4R- and subsequently the CRH receptor-signaling pathways.

Matsuda K, Kojima K, Wada K, Maruyama K, Leprince J, Tonon MC, Uchiyama M, Vaudry H

Journal of molecular neuroscience : MN21 Mar 2010Cited by 20 (Europe PMC)

PMID20306309 (opens in a new tab)DOI10.1007/s12031-010-9346-9 (opens in a new tab)PepBankPUB-20306309
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In goldfish, intracerebroventricular melanotan II (MC4R agonist) at 100 pmol/g body weight significantly increased CRH mRNA expression.

    In plain wordsIn goldfish, melanotan II given into the brain raised the activity of the gene for corticotropin-releasing hormone.

    Peptide
    Melanotan II
    Outcome
    IncreaseCRH mRNA expression
    Study

    goldfishn: not reported in source

    Goldfish
    Outcome group
    Receptor activity and mechanism · Metabolic and weight
    Studied dose
    100 pmol/g body weight · intracerebroventricularAs given in this study (goldfish).

    Source sentences

    Summary
    ICV injection of the MC4R agonist, melanotan II (100 pmol/g BW), significantly enhanced CRH mRNA expression.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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