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Study · Animal study (in vivo) · rat · 2010

2 results

Evaluation of the lack of anorectic effect of intracerebroventricular insulin in rats.

Jessen L, Clegg DJ, Bouman SD

American journal of physiology. Regulatory, integrative and comparative physiology28 Oct 2009Cited by 24 (Europe PMC)

PMID19864335 (opens in a new tab)DOI10.1152/ajpregu.90736.2008 (opens in a new tab)PepBankPUB-19864335
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intracerebroventricular melanotan II, used as a positive control, significantly reduced food intake.

    In plain wordsIn rats, melanotan II given into the brain reduced food intake.

    Peptide
    Melanotan II
    Outcome
    DecreaseFood intake
    Study

    ratn: not reported in source

    Rats fed ad libitum
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated · intracerebroventricularAs given in this study (rat).

    Source sentences

    Summary
    Melanotan-II was also injected intracerebroventricularly as a positive control, and significantly reduced food intake and body weight, suggesting that our intracerebroventricular model is able to show anorectic effects.
    1 context sentence
    Summary · context
    We used acute intracerebroventricular insulin injections to compare food intake and body weight in rats fed ad libitum.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intracerebroventricular melanotan II, used as a positive control, significantly reduced body weight.

    In plain wordsIn rats, melanotan II given into the brain reduced body weight.

    Peptide
    Melanotan II
    Outcome
    DecreaseBody weight
    Study

    ratn: not reported in source

    Rats fed ad libitum
    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    Dose not stated · intracerebroventricularAs given in this study (rat).

    Source sentences

    Summary
    Melanotan-II was also injected intracerebroventricularly as a positive control, and significantly reduced food intake and body weight, suggesting that our intracerebroventricular model is able to show anorectic effects.
    1 context sentence
    Summary · context
    We used acute intracerebroventricular insulin injections to compare food intake and body weight in rats fed ad libitum.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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