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Study · Animal study (in vivo) · mouse · 2016

1 result

Lateral hypothalamic melanocortin receptor signaling modulates binge-like ethanol drinking in C57BL/6J mice.

Sprow GM, Rinker JA, Lowery-Gointa EG, Sparrow AM, Navarro M, Thiele TE

Addiction biology15 May 2015Cited by 21 (Europe PMC)

PMID25975524 (opens in a new tab)PMCIDPMC4644727 (opens in a new tab)DOI10.1111/adb.12264 (opens in a new tab)PepBankPUB-25975524
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In male C57BL/6J mice, melanotan II delivered into the lateral hypothalamus blunted binge-like ethanol consumption.

    In plain wordsIn mice, melanotan II given into a brain area reduced binge-like alcohol drinking.

    Peptide
    Melanotan II
    Outcome
    DecreaseBinge-like ethanol consumption
    Study

    mousen: not reported in source

    Male C57BL/6J mice, drinking in the dark
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated · intra-lateral hypothalamusAs given in this study (mouse).

    Source sentences

    Summary
    We found that the nonselective MCR agonist melanotan-II (MTII) blunted
    1 context sentence
    Summary · context
    binge-like ethanol consumption when delivered into the LH.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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