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Study · Animal study (in vivo) · 2005

1 result

Anxiolytic-like effect of a selective and non-peptidergic melanocortin 4 receptor antagonist, MCL0129, in a social interaction test.

Shimazaki T, Chaki S

Pharmacology, biochemistry, and behavior16 Jan 2005Cited by 21 (Europe PMC)

PMID15740781 (opens in a new tab)DOI10.1016/j.pbb.2004.11.014 (opens in a new tab)PepBankPUB-15740781
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In an animal social interaction test, MT II dose-dependently and significantly reduced the time spent in social interaction.

    In plain wordsIn animals, MT II reduced time spent in social interaction, and more so at higher doses.

    Peptide
    Melanotan II
    Outcome
    DecreaseTime spent in social interaction
    Study

    n: not reported in source

    social interaction test
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    MT II dose-dependently and significantly reduced the time spent in social interaction.
    1 context sentence
    Summary · context
    The social interaction test is an animal behavioral test of anxiety.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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