Melanotan II studies: 324 papers with results
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- Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area.
Cui H · The Journal of comparative neurology · 2012
Animal study (in vivo) · mouse · 1 result
- Differential role of melanocortins in mediating leptin's central effects on feeding and reproduction.
Hohmann JG · American journal of physiology. Regulatory, integrative and comparative physiology · 2000
Animal study (in vivo) · 3 results
- Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents.
Chaki S · European journal of pharmacology · 2003
Animal study (in vivo) · rat · 1 result
- Melanocortin Receptor Agonists Facilitate Oxytocin-Dependent Partner Preference Formation in the Prairie Vole.
Modi ME · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015
Animal study (in vivo) · meadow vole and prairie vole · 6 results
- Role of adrenergic activity in pressor responses to chronic melanocortin receptor activation.
Kuo JJ · Hypertension (Dallas, Tex. : 1979) · 2004
Animal study (in vivo) · rat · 7 results
- Melanocortin 3/4 receptors in paraventricular nucleus modulate sympathetic outflow and blood pressure.
Li P · Experimental physiology · 2013
Animal study (in vivo) · rat · 4 results
- Magel2 is required for leptin-mediated depolarization of POMC neurons in the hypothalamic arcuate nucleus in mice.
Mercer RE · PLoS genetics · 2013
Animal study (in vivo) · mouse · 1 result
- Centrally administered MTII affects feeding, drinking, temperature, and activity in the Sprague-Dawley rat.
Murphy B · Journal of applied physiology (Bethesda, Md. : 1985) · 2000
Animal study (in vivo) · rat · 7 results
- Central melanocortin receptor agonist reduces spontaneous and scheduled meal size but does not augment duodenal preload-induced feeding inhibition.
Azzara AV · Physiology & behavior · 2002
Animal study (in vivo) · rat · 8 results
- Natural and synthetic agonists of the melanocortin receptor type 3 possess anti-inflammatory properties.
Getting SJ · Journal of leukocyte biology · 2001
Animal study (in vivo) · mouse · 6 results
- Central mechanisms of adiposity in adult female mice with androgen excess.
Nohara K · Obesity (Silver Spring, Md.) · 2014
Animal study (in vivo) · mouse · 1 result
- Ac-Nle-c[Asp-His-DPhe-Arg-Trp-Lys]-NH2 induces penile erection via brain and spinal melanocortin receptors.
Wessells H · Neuroscience · 2003
Animal study (in vivo) · rat · 9 results
- Melanocortin activity in the amygdala controls appetite for dietary fat.
Boghossian S · American journal of physiology. Regulatory, integrative and comparative physiology · 2010
Animal study (in vivo) · rat · 5 results
- Melanocortin peptides affect the motivation to feed in rainbow trout (Oncorhynchus mykiss).
Schjolden J · General and comparative endocrinology · 2009
Animal study (in vivo) · rainbow trout (oncorhynchus mykiss) · 1 result
- Role of the Paraventricular Nucleus of the Hypothalamus in the Sympathoexcitatory Effects of Leptin.
Shi Z · Hypertension (Dallas, Tex. : 1979) · 2015
Animal study (in vivo) · rat · 3 results
- Orexin-A hyperphagia: hindbrain participation in consummatory feeding responses.
Baird JP · Endocrinology · 2009
Animal study (in vivo) · rat · 1 result
- Melanocortin 4 receptor-mediated hyperphagia and activation of neuropeptide Y expression in the dorsomedial hypothalamus during lactation.
Chen P · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004
Animal study (in vivo) · rat · 4 results
- Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria.
Chhabra KH · Diabetes · 2016
Animal study (in vivo) · mouse · 2 results
- Central melanocortin signaling restores skeletal muscle AMP-activated protein kinase phosphorylation in mice fed a high-fat diet.
Tanaka T · Cell metabolism · 2007
Animal study (in vivo) · mouse · 4 results
- Syndecan-3 modulates food intake by interacting with the melanocortin/AgRP pathway.
Reizes O · Annals of the New York Academy of Sciences · 2003
Animal study (in vivo) · mouse · 1 result
- The melanocortin receptor MCR4 controls fat consumption.
Samama P · Regulatory peptides · 2003
Animal study (in vivo) · mouse · 2 results
- Agouti-related peptide plays a critical role in leptin's effects on female puberty and reproduction.
Sheffer-Babila S · American journal of physiology. Endocrinology and metabolism · 2013
Animal study (in vivo) · 1 result
- The role of the melanocortin system and the melanocortin-4 receptor in ring dove (Streptopelia risoria) feeding behavior.
Strader AD · Brain research · 2003
Animal study (in vivo) · ring dove · 1 result
- MTII-induced reduction of voluntary ethanol drinking is blocked by pretreatment with AgRP-(83-132).
Navarro M · Neuropeptides · 2003
Animal study (in vivo) · mouse · 6 results
- A functional melanocortin system may be required for chronic CNS-mediated antidiabetic and cardiovascular actions of leptin.
da Silva AA · Diabetes · 2009
Animal study (in vivo) · rat · 3 results
- Energetic responses are triggered by caudal brainstem melanocortin receptor stimulation and mediated by local sympathetic effector circuits.
Skibicka KP · Endocrinology · 2008
Animal study (in vivo) · rat · 11 results
- Effects of melanocortin receptor activation and blockade on ethanol intake: a possible role for the melanocortin-4 receptor.
Navarro M · Alcoholism, clinical and experimental research · 2005
Animal study (in vivo) · mouse · 2 results
- Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII.
Clegg DJ · Endocrinology · 2003
Animal study (in vivo) · rat · 1 result
- Exploring the site of anorectic action of peripherally administered synthetic melanocortin peptide MT-II in rats.
Trivedi P · Brain research · 2003
Animal study (in vivo) · rat · 5 results
- Effects of melanocortin receptor ligands on ethanol intake and opioid peptide levels in alcohol-preferring AA rats.
Ploj K · Brain research bulletin · 2002
Animal study (in vivo) · rat · 5 results
- Ventromedial hypothalamic melanocortin receptor activation: regulation of activity energy expenditure and skeletal muscle thermogenesis.
Gavini CK · The Journal of physiology · 2016
Animal study (in vivo) · rat · 8 results
- The leptin-like effects of 3-d peripheral administration of a melanocortin agonist are more marked in genetically obese Zucker (fa/fa) than in lean rats.
Cettour-Rose P · Endocrinology · 2002
Animal study (in vivo) · rat · 8 results
- Food conversion is transiently affected during 4-week chronic administration of melanocortin agonist and antagonist in rats.
Jonsson L · The Journal of endocrinology · 2002
Animal study (in vivo) · rat · 5 results
- Characterization of a novel melanocortin receptor-containing node in the SNS outflow circuitry to brown adipose tissue involved in thermogenesis.
Vaughan CH · Brain research · 2011
Animal study (in vivo) · siberian hamster · 2 results
- Melanocortins mimic the effects of leptin to restore reproductive function in lean hypogonadotropic ewes.
Backholer K · Neuroendocrinology · 2010
Animal study (in vivo) · sheep · 1 result
- The melanocortin receptor agonist MTII augments the rewarding effect of amphetamine in ad-libitum-fed and food-restricted rats.
Cabeza de Vaca S · Psychopharmacology · 2002
Animal study (in vivo) · rat · 5 results
- Behavioral processes underlying the intake suppressive effects of melanocortin 3/4 receptor activation in the rat.
Williams DL · Psychopharmacology · 2002
Animal study (in vivo) · rat · 4 results
- Effect of MTII on food intake and brain c-Fos in melanocortin-3, melanocortin-4, and double MC3 and MC4 receptor knockout mice.
Rowland NE · Peptides · 2010
Animal study (in vivo) · mouse · 8 results
- Thermogenesis activated by central melanocortin signaling is dependent on neurons in the rostral raphe pallidus (rRPa) area.
Fan W · Brain research · 2007
Animal study (in vivo) · mouse and rat · 4 results
- In vitro and in vivo induction of heme oxygenase 1 in mouse macrophages following melanocortin receptor activation.
Lam CW · Journal of immunology (Baltimore, Md. : 1950) · 2005
Animal study (in vivo) · mouse · 6 results
- Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression.
Li G · The Journal of endocrinology · 2004
Animal study (in vivo) · rat · 10 results
- Modulation of melanocortin-induced changes in spinal nociception by mu-opioid receptor agonist and antagonist in neuropathic rats.
Starowicz K · Neuroreport · 2002
Animal study (in vivo) · rat · 4 results
- Response of neuropeptide Y-deficient mice to feeding effectors.
Hollopeter G · Regulatory peptides · 1998
Animal study (in vivo) · mouse · 1 result
- Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity.
Cui J · The Journal of clinical investigation · 2016
Animal study (in vivo) · mouse · 1 result
- Altered hypothalamic signaling and responses to food deprivation in rats fed a low-carbohydrate diet.
Kinzig KP · Obesity research · 2005
Animal study (in vivo) · rat · 1 result
- The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat.
Raposinho PD · Journal of neuroendocrinology · 2003
Animal study (in vivo) · rat · 10 results
- Aged-obese rats exhibit robust responses to a melanocortin agonist and antagonist despite leptin resistance.
Zhang Y · Neurobiology of aging · 2004
Animal study (in vivo) · rat · 4 results
- Leptin-induced leptin resistant rats exhibit enhanced responses to the melanocortin agonist MT II.
Scarpace PJ · Neuropharmacology · 2003
Animal study (in vivo) · rat · 3 results
- Chronic application of MTII in a rat model of obesity results in sustained weight loss.
Hamilton BS · Obesity research · 2002
Animal study (in vivo) · rat · 7 results
- Nanostructured porous silicon microparticles enable sustained peptide (Melanotan II) delivery.
Kilpeläinen M · European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2011
Animal study (in vivo) · 4 results