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Study · Animal study (in vivo) · rainbow trout (oncorhynchus mykiss) · 2009

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Melanocortin peptides affect the motivation to feed in rainbow trout (Oncorhynchus mykiss).

Schjolden J, Schiöth HB, Larhammar D, Winberg S, Larson ET

General and comparative endocrinology8 Nov 2008Cited by 50 (Europe PMC)

PMID19027741 (opens in a new tab)DOI10.1016/j.ygcen.2008.11.003 (opens in a new tab)PepBankPUB-19027741
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In juvenile rainbow trout, intracerebroventricular MTII at 3 nM decreased food intake compared with control.

    In plain wordsIn juvenile rainbow trout, MTII injected into the brain reduced food intake compared with control fish.

    Peptide
    Melanotan II
    Outcome
    DecreaseFood intake 1 h after injection
    Study

    rainbow trout (Oncorhynchus mykiss)n: not reported in source

    in vivo, juvenile rainbow trout
    Comparator
    Control (saline-injected and untreated fish)
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    3 nM · intracerebroventricular injectionAs given in this study (rainbow trout (Oncorhynchus mykiss)).

    Source sentences

    Summary
    treatment with MTII significantly decreased food intake at 3 nM compared to control
    2 context sentences
    Summary · context
    In this study, we investigated the effects of one melanocortin receptor (MCR) agonist and two antagonists on food intake in juvenile rainbow trout.
    Summary · context
    Baseline food intake was established prior to 1 microl intracerebroventricular injection (ICV) of the non-specific agonist MTII, the MC4R antagonist HS024 and the MC3/4R antagonist SHU9119 at concentrations of 0.3, 1 or 3 nM.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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