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Study · Animal study (in vivo) · mouse · 1998

1 result

Response of neuropeptide Y-deficient mice to feeding effectors.

Hollopeter G, Erickson JC, Seeley RJ, Marsh DJ, Palmiter RD

Regulatory peptides1 Sept 1998Cited by 39 (Europe PMC)

PMID9802433 (opens in a new tab)DOI10.1016/s0167-0115(98)00092-5 (opens in a new tab)PepBankPUB-09802433
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In NPY-deficient mice, the response to the MC4R agonist MTII was unaltered.

    In plain wordsIn mice lacking NPY, MTII still had its normal effect on feeding.

    Peptide
    Melanotan II
    Outcome
    No significant changeFeeding inhibition by MTII in NPY-deficient mice
    Study

    mousen: not reported in source

    NPY-deficient (NPY-/-) mice
    Comparator
    Wild-type (NPY+/+) mice
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    a melanocortin 4 receptor (MC4R) agonist, MTII, was unaltered in NPY-/- mice
    1 context sentence
    Summary · context
    In this study, we investigate the response of NPY-deficient (NPY-/-) mice to anorexic and orexigenic treatments.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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