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Study · Animal study (in vivo) · mouse · 2014

1 result

Central mechanisms of adiposity in adult female mice with androgen excess.

Nohara K, Laque A, Allard C, Münzberg H, Mauvais-Jarvis F

Obesity (Silver Spring, Md.)19 Feb 2014Cited by 53 (Europe PMC)

PMID24639082 (opens in a new tab)PMCIDPMC4037375 (opens in a new tab)DOI10.1002/oby.20719 (opens in a new tab)PepBankPUB-24639082
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In female mice with chronic androgen (DHT) excess, the melanocortin 4 receptor agonist melanotan II failed to suppress body weight.

    In plain wordsIn female mice given excess androgen, melanotan II did not lower body weight.

    Peptide
    Melanotan II
    Outcome
    No significant changeBody weight suppression by melanotan-II in DHT-exposed mice
    Study

    mousen: not reported in source

    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    failure of the melanocortin 4 receptor agonist melanotan-II to suppress body weight.
    1 context sentence
    Summary · context
    To address this issue, female mice to chronic androgen excess using 5α-dihydrotestosterone (DHT) and studied the regulation of energy homeostasis was exposed.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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