Skip to content

Study · Animal study (in vivo) · 2013

1 result

Agouti-related peptide plays a critical role in leptin's effects on female puberty and reproduction.

Sheffer-Babila S, Sun Y, Israel DD, Liu SM, Neal-Perry G, Chua SC Jr

American journal of physiology. Endocrinology and metabolism29 Oct 2013Cited by 47 (Europe PMC)

PMID24169048 (opens in a new tab)PMCIDPMC3882375 (opens in a new tab)DOI10.1152/ajpendo.00241.2013 (opens in a new tab)PepBankPUB-24169048
Source linkPubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    MC4R activation with MTII induced FOS expression in TAC2 neurons.

    In plain wordsIn animals, MTII turned on the activity marker FOS in TAC2 nerve cells.

    Peptide
    Melanotan II
    Outcome
    IncreaseFOS expression in TAC2 neurons
    Study

    n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Additionally, MC4R activation with MTII induced FOS expression in TAC2 neurons, supporting the concept of melanocortinergic regulation of TAC2 neurons.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.