Hexarelin studies: 245 papers with results
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- Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia.
Conte E · Journal of cachexia, sarcopenia and muscle · 2017
Animal study (in vivo) · rat · 3 results
- Novel hexarelin analogs stimulate feeding in the rat through a mechanism not involving growth hormone release.
Torsello A · European journal of pharmacology · 1998
Animal study (in vivo) · rat · 4 results
- A growth hormone-releasing peptide that binds scavenger receptor CD36 and ghrelin receptor up-regulates sterol transporters and cholesterol efflux in macrophages through a peroxisome proliferator-activated receptor gamma-dependent pathway.
Avallone R · Molecular endocrinology (Baltimore, Md.) · 2006
Animal study (in vivo) · mouse · 10 results
- Evidence for a central inhibitory role of growth hormone secretagogues and ghrelin on gastric acid secretion in conscious rats.
Sibilia V · Neuroendocrinology · 2002
Animal study (in vivo) · rat · 5 results
- Cardiac ischemia and impairment of vascular endothelium function in hearts from growth hormone-deficient rats: protection by hexarelin.
De Gennaro Colonna V · European journal of pharmacology · 1997
Animal study (in vivo) · rat · 6 results
- Metabolism of growth hormone releasing peptides.
Thomas A · Analytical chemistry · 2012
Animal study (in vivo) · rat · 5 results
- Ghrelin plays a minor role in the physiological control of cardiac function in the rat.
Torsello A · Endocrinology · 2003
Animal study (in vivo) · rat · 3 results
- Hexarelin suppresses high lipid diet and vitamin D3-induced atherosclerosis in the rat.
Pang J · Peptides · 2010
Animal study (in vivo) · rat · 10 results
- Growth hormone secretagogues hexarelin and JMV2894 protect skeletal muscle from mitochondrial damages in a rat model of cisplatin-induced cachexia.
Sirago G · Scientific reports · 2017
Animal study (in vivo) · rat · 1 result
- Differential orexigenic effects of hexarelin and its analogs in the rat hypothalamus: indication for multiple growth hormone secretagogue receptor subtypes.
Torsello A · Neuroendocrinology · 2000
Animal study (in vivo) · rat · 6 results
- Growth hormone secretagogues modulate the electrical and contractile properties of rat skeletal muscle through a ghrelin-specific receptor.
Pierno S · British journal of pharmacology · 2003
Animal study (in vivo) · rat · 6 results
- Mechanism of action of hexarelin and GHRP-6: analysis of the involvement of GHRH and somatostatin in the rat.
Conley LK · Neuroendocrinology · 1995
Animal study (in vivo) · rat · 4 results
- Beneficial effects of desacyl-ghrelin, hexarelin and EP-80317 in models of status epilepticus.
Biagini G · European journal of pharmacology · 2011
Animal study (in vivo) · rat · 3 results
- Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat.
Xu X · American journal of physiology. Heart and circulatory physiology · 2012
Animal study (in vivo) · rat · 11 results
- A growth hormone-releasing peptide promotes mitochondrial biogenesis and a fat burning-like phenotype through scavenger receptor CD36 in white adipocytes.
Rodrigue-Way A · Endocrinology · 2007
Animal study (in vivo) · mouse · 10 results
- Growth hormone-releasing peptide hexarelin reduces neonatal brain injury and alters Akt/glycogen synthase kinase-3beta phosphorylation.
Brywe KG · Endocrinology · 2005
Animal study (in vivo) · rat · 9 results
- Direct nose-to-brain transfer of a growth hormone releasing neuropeptide, hexarelin after intranasal administration to rabbits.
Yu H · International journal of pharmaceutics · 2009
Animal study (in vivo) · rabbit · 6 results
- Zebrafish (Danio rerio) water tank model for the investigation of drug metabolism: Progress, outlook, and challenges.
Sardela VF · Drug testing and analysis · 2018
Animal study (in vivo) · zebrafish · 2 results
- Hexarelin treatment in male ghrelin knockout mice after myocardial infarction.
Mao Y · Endocrinology · 2013
Animal study (in vivo) · mouse · 10 results
- Early tolerance to the hypophagic effect of the cannabinoid receptor antagonist SR141716 does not impede blockade of an orexigenic stimulus.
Rigamonti AE · European journal of pharmacology · 2006
Animal study (in vivo) · rat · 3 results
- The Growth Hormone Secretagogue Hexarelin Protects Rat Cardiomyocytes From in vivo Ischemia/Reperfusion Injury Through Interleukin-1 Signaling Pathway.
Huang J · International heart journal · 2017
Animal study (in vivo) · rat · 7 results
- Growth hormone and hexarelin prevent endothelial vasodilator dysfunction in aortic rings of the hypophysectomized rat.
Rossoni G · Journal of cardiovascular pharmacology · 1999
Animal study (in vivo) · rat · 5 results
- Endocrine, metabolic and cardioprotective effects of hexarelin in obese Zucker rats.
De Gennaro-Colonna V · The Journal of endocrinology · 2000
Animal study (in vivo) · rat · 14 results
- EP 60761 and EP 50885, two hexarelin analogues, induce penile erection in rats.
Melis MR · European journal of pharmacology · 2000
Animal study (in vivo) · rat · 2 results
- Hexarelin exhibits protective activity against cardiac ischaemia in hearts from growth hormone-deficient rats.
Berti F · Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 1998
Animal study (in vivo) · rat · 3 results
- Hexarelin, a potent GHRP analogue: interactions with GHRH and clonidine in young and aged dogs.
Cella SG · Peptides · 1995
Animal study (in vivo) · dog · 4 results
- JMV2894, a novel growth hormone secretagogue, accelerates body mass recovery in an experimental model of cachexia.
Bresciani E · Endocrine · 2017
Animal study (in vivo) · rat · 4 results
- Penile erection induced by EP 80661 and other hexarelin peptide analogues: involvement of paraventricular nitric oxide.
Melis MR · European journal of pharmacology · 2001
Animal study (in vivo) · rat · 2 results
- Effects of hexarelin (a ghrelin analogue) on fertilisation and the pre- and postnatal development of mice.
Luque EM · Reproduction, fertility, and development · 2010
Animal study (in vivo) · mouse · 5 results
- Effects of repeated doses and continuous infusions of the growth hormone-releasing peptide hexarelin in conscious male rats.
Conley LK · The Journal of endocrinology · 1998
Animal study (in vivo) · rat · 9 results
- Partial recovery of skeletal muscle sodium channel properties in aged rats chronically treated with growth hormone or the GH-secretagogue hexarelin.
Desaphy JF · The Journal of pharmacology and experimental therapeutics · 1998
Animal study (in vivo) · rat · 4 results
- Hexarelin alleviates apoptosis on ischemic acute kidney injury via MDM2/p53 pathway.
Guan C · European journal of medical research · 2023
Animal study (in vivo) · rat · 9 results
- Stimulation of endogenous pulsatile growth hormone secretion by activation of growth hormone secretagogue receptor reduces the fat accumulation and improves the insulin sensitivity in obese mice.
Huang Z · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
Animal study (in vivo) · mouse · 12 results
- Hexarelin treatment preserves myocardial function and reduces cardiac fibrosis in a mouse model of acute myocardial infarction.
McDonald H · Physiological reports · 2018
Animal study (in vivo) · mouse · 11 results
- Effects of hexarelin against acid-independent and acid-dependent ulcerogens in the rat.
Sibilia V · Peptides · 2004
Animal study (in vivo) · rat · 6 results
- Hexarelin, a growth hormone - releasing peptide, counteracts bone loss in gonadectomized male rats.
Sibilia V · Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 1999
Animal study (in vivo) · rat · 10 results
- Hexarelin, a growth hormone-releasing peptide, discloses protectant activity against cardiovascular damage in rats with isolated growth hormone deficiency.
De Gennaro Colonna V · Cardiologia (Rome, Italy) · 1997
Animal study (in vivo) · rat · 5 results
- Hexarelin Protects Rodent Pancreatic Β-Cells Function from Cytotoxic Effects of Streptozotocin Involving Mitochondrial Signalling Pathways In Vivo and In Vitro.
Zhao Y · PloS one · 2016
Animal study (in vivo) · rat · 10 results
- One dose of oral hexarelin protects chronic cardiac function after myocardial infarction.
Mao Y · Peptides · 2014
Animal study (in vivo) · mouse · 7 results
- Reproductive performance and fertility in male and female adult mice chronically treated with hexarelin.
Puechagut PB · Reproduction, fertility, and development · 2012
Animal study (in vivo) · mouse · 4 results
- Hexarelin attenuates atherosclerosis via inhibiting LOX-1-NF-κB signaling pathway-mediated macrophage ox-LDL uptake in ApoE-/- mice.
Cheng XL · Peptides · 2019
Animal study (in vivo) · mouse · 15 results
- Kinetics and disposition of hexarelin, a peptidic growth hormone secretagogue, in rats.
Roumi M · Drug metabolism and disposition: the biological fate of chemicals · 2000
Animal study (in vivo) · rat · 15 results
- Modulation of PTEN by hexarelin attenuates coronary artery ligation-induced heart failure in rats
Agbo E · Turkish journal of medical sciences · 2019
Animal study (in vivo) · rat · 6 results
- Hexarelin modulates the expression of growth hormone secretagogue receptor type 1a mRNA at hypothalamic and pituitary sites.
Bresciani E · Neuroendocrinology · 2004
Animal study (in vivo) · rat · 5 results
- Mechanism of action of Hexarelin. I. Growth hormone-releasing activity in the rat.
Torsello A · European journal of endocrinology · 1996
Animal study (in vivo) · rat · 8 results
- Ghrelin receptor agonist hexarelin attenuates antinociceptive tolerance to morphine in rats.
Baser T · Canadian journal of physiology and pharmacology · 2021
Animal study (in vivo) · rat · 2 results
- Hexarelin targets neuroinflammatory pathways to preserve cardiac morphology and function in a mouse model of myocardial ischemia-reperfusion.
McDonald H · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020
Animal study (in vivo) · mouse · 7 results
- Hexarelin, a Growth Hormone Secretagogue, Improves Lipid Metabolic Aberrations in Nonobese Insulin-Resistant Male MKR Mice.
Mosa R · Endocrinology · 2017
Animal study (in vivo) · mouse · 8 results
- The growth hormone secretagogue hexarelin increases cell proliferation in neurogenic regions of the mouse hippocampus.
Barlind A · Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2010
Animal study (in vivo) · mouse · 1 result
- Hexarelin, a growth hormone secretagogue, protects the isolated rat heart from ventricular dysfunction produced by exposure to calcium-free medium.
Rossoni G · Pharmacological research · 2000
Animal study (in vivo) · rat · 7 results