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Study · In vitro (cells) · 2021

1 result

Resveratrol attenuates excessive ethanol exposure-induced β-cell senescence in rats: A critical role for the NAD+/SIRT1-p38MAPK/p16 pathway.

Luo G, Xiao L, Wang D, Wang N, Luo C, Yang X, Hao L

The Journal of nutritional biochemistry14 Dec 2020Cited by 24 (Europe PMC)

PMID33326842 (opens in a new tab)DOI10.1016/j.jnutbio.2020.108568 (opens in a new tab)PepBankPUB-33326842
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In ethanol-treated INS-1 cells, NMN supplementation reversed beta-cell senescence.

    In plain wordsIn cells from the INS-1 line exposed to ethanol, NMN reversed beta-cell senescence.

    Peptide
    NMN (nicotinamide mononucleotide)
    Outcome
    DecreaseBeta-cell senescence
    Study

    n: not reported in source

    Ethanol-treated INS-1 cells
    Outcome group
    Aging markers · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Furthermore, supplementation with NAD+ inducer nicotinamide mononucleotide, SIRT1 activator SRT1720 or p38MAPK inhibitor SB203580 effectively reversed ethanol-induced β-cell senescence
    1 context sentence
    Summary · context
    while supplementation with SIRT1 inhibitor Ex527 or NAD+ inhibitor FK866 abrogated resveratrol-mediated antisenescence effects in INS-1 cells.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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