In superfused medial basal hypothalami from female rats, thymosin alpha‑1 did not stimulate secretion of luteinizing hormone-releasing factor, unlike thymosin fraction 5 and thymosin beta 4.
In plain wordsIn rat tissue in lab tests, thymosin alpha‑1 did not trigger release of a reproductive hormone signal, unlike thymosin beta 4.
- Peptide
- Thymosin alpha-1
- Outcome
- No significant changeLuteinizing hormone-releasing factor secretion
- Study
ratn: not reported in source
Superfused medial basal hypothalami from random cycling female rats- Comparator
- Thymosin fraction 5 and thymosin beta 4
- Outcome group
- Sex hormones and fertility · Endocrine and hormones
- Studied dose
- Dose not stated
Source sentences
Partially purified thymosin fraction 5 and one of its synthetic peptide components, thymosin beta 4, but not thymosin alpha 1, stimulated secretion of luteinizing hormone--releasing factor from superfused medial basal hypothalami from random cycling female rats.