Exenatide (exendin-4) studies: 530 papers with results
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- Inflammation-Induced Adverse Pregnancy and Neonatal Outcomes Can Be Improved by the Immunomodulatory Peptide Exendin-4.
Garcia-Flores V · Frontiers in immunology · 2018
Animal study (in vivo) · 9 results
- Pharmacokinetics and pharmacodynamics of exenatide following alternate routes of administration.
Gedulin BR · International journal of pharmaceutics · 2008
Animal study (in vivo) · mouse and rat · 14 results
- Islet transplantation outcomes in mice are better with fresh islets and exendin-4 treatment.
King A · Diabetologia · 2005
Animal study (in vivo) · mouse · 2 results
- Exendin-4 attenuates brain mitochondrial toxicity through PI3K/Akt-dependent pathway in amyloid beta (1-42)-induced cognitive deficit rats.
Garabadu D · Neurochemistry international · 2019
Animal study (in vivo) · rat · 16 results
- Sustained release of exendin-4 from tannic acid/Fe (III) nanoparticles prolongs blood glycemic control in a mouse model of type II diabetes.
He Z · Journal of controlled release : official journal of the Controlled Release Society · 2019
Animal study (in vivo) · mouse · 9 results
- Effects of the GLP-1 Agonist Exendin-4 on Intravenous Ethanol Self-Administration in Mice.
Sørensen G · Alcoholism, clinical and experimental research · 2016
Animal study (in vivo) · mouse · 2 results
- Exendin-4 attenuates renal tubular injury by decreasing oxidative stress and inflammation in streptozotocin-induced diabetic mice.
Sancar-Bas S · Growth factors (Chur, Switzerland) · 2015
Animal study (in vivo) · mouse · 15 results
- Exendin-4 alleviates retinal vascular leakage by protecting the blood-retinal barrier and reducing retinal vascular permeability in diabetic Goto-Kakizaki rats.
Fan Y · Experimental eye research · 2014
Animal study (in vivo) · rat · 9 results
- Repeated administration of exendin-4 reduces focal cerebral ischemia-induced infarction in rats.
Briyal S · Brain research · 2012
Animal study (in vivo) · rat · 7 results
- The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics.
Chae SY · Journal of controlled release : official journal of the Controlled Release Society · 2010
Animal study (in vivo) · mouse · 1 result
- Exendin-4, a glucagon-like peptide 1 receptor agonist, protects cholangiocytes from apoptosis.
Marzioni M · Gut · 2009
Animal study (in vivo) · rat · 8 results
- Synthesis of CSK-DEX-PLGA Nanoparticles for the Oral Delivery of Exenatide to Improve Its Mucus Penetration and Intestinal Absorption.
Song Y · Molecular pharmaceutics · 2019
Animal study (in vivo) · rat · 8 results
- Combination of obesity and high-fat feeding diminishes sensitivity to GLP-1R agonist exendin-4.
Duca FA · Diabetes · 2013
Animal study (in vivo) · rat · 2 results
- Differences in the central anorectic effects of glucagon-like peptide-1 and exendin-4 in rats.
Barrera JG · Diabetes · 2009
Animal study (in vivo) · mouse and rat · 4 results
- Long-term oral administration of Exendin-4 to control type 2 diabetes in a rat model.
Suzuki K · Journal of controlled release : official journal of the Controlled Release Society · 2019
Animal study (in vivo) · rat · 5 results
- Dose combinations of exendin-4 and salmon calcitonin produce additive and synergistic reductions in food intake in nonhuman primates.
Bello NT · American journal of physiology. Regulatory, integrative and comparative physiology · 2010
Animal study (in vivo) · rhesus monkey · 8 results
- Dose-response for glycaemic and metabolic changes 28 days after single injection of long-acting release exenatide in diabetic fatty Zucker rats.
Gedulin BR · Diabetologia · 2005
Animal study (in vivo) · rat · 3 results
- Phasic dopamine responses to a food-predictive cue are suppressed by the glucagon-like peptide-1 receptor agonist Exendin-4.
Konanur VR · Physiology & behavior · 2020
Animal study (in vivo) · rat · 4 results
- Exendin-4 Inhibits Matrix Metalloproteinase-9 Activation and Reduces Infarct Growth After Focal Cerebral Ischemia in Hyperglycemic Mice.
Kuroki T · Stroke · 2016
Animal study (in vivo) · mouse · 5 results
- Exendin-4 attenuates adverse cardiac remodelling in streptozocin-induced diabetes via specific actions on infiltrating macrophages.
Tate M · Basic research in cardiology · 2016
Animal study (in vivo) · mouse · 9 results
- Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection.
Huang HJ · PloS one · 2012
Animal study (in vivo) · mouse · 1 result
- A new orally available glucagon-like peptide-1 receptor agonist, biotinylated exendin-4, displays improved hypoglycemic effects in db/db mice.
Jin CH · Journal of controlled release : official journal of the Controlled Release Society · 2009
Animal study (in vivo) · mouse · 4 results
- The glucagon like peptide 1 analogue, exendin-4, attenuates oxidative stress-induced retinal cell death in early diabetic rats through promoting Sirt1 and Sirt3 expression.
Zeng Y · Experimental eye research · 2016
Animal study (in vivo) · rat · 9 results
- Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy.
Vyas AK · PloS one · 2011
Animal study (in vivo) · mouse · 9 results
- Brain Site-Specific Inhibitory Effects of the GLP-1 Analogue Exendin-4 on Alcohol Intake and Operant Responding for Palatable Food.
Colvin KJ · International journal of molecular sciences · 2020
Animal study (in vivo) · rat · 4 results
- Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents.
Arakawa M · Biochemical and biophysical research communications · 2009
Animal study (in vivo) · mouse · 6 results
- The anti-diabetic drug exenatide, a glucagon-like peptide-1 receptor agonist, counteracts hepatocarcinogenesis through cAMP-PKA-EGFR-STAT3 axis.
Zhou M · Oncogene · 2017
Animal study (in vivo) · mouse · 15 results
- Exendin-4 increases blood glucose levels acutely in rats by activation of the sympathetic nervous system.
Pérez-Tilve D · American journal of physiology. Endocrinology and metabolism · 2010
Animal study (in vivo) · rat · 6 results
- Exenatide Delays the Progression of Nonalcoholic Fatty Liver Disease in C57BL/6 Mice, Which May Involve Inhibition of the NLRP3 Inflammasome through the Mitophagy Pathway.
Shao N · Gastroenterology research and practice · 2018
Animal study (in vivo) · mouse · 16 results
- Blast traumatic brain injury-induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4.
Tweedie D · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2016
Animal study (in vivo) · mouse · 3 results
- Stimulation of glucagon-like peptide-1 receptor through exendin-4 preserves myocardial performance and prevents cardiac remodeling in infarcted myocardium.
DeNicola M · American journal of physiology. Endocrinology and metabolism · 2014
Animal study (in vivo) · mouse · 11 results
- Self-assembled glycol chitosan nanogels containing palmityl-acylated exendin-4 peptide as a long-acting anti-diabetic inhalation system.
Lee J · Journal of controlled release : official journal of the Controlled Release Society · 2012
Animal study (in vivo) · mouse · 3 results
- Exenatide regulates Th17/Treg balance via PI3K/Akt/FoxO1 pathway in db/db mice.
Xu Q · Molecular medicine (Cambridge, Mass.) · 2022
Animal study (in vivo) · mouse · 8 results
- Anti-inflammatory Effect of Glucagon Like Peptide-1 Receptor Agonist, Exendin-4, through Modulation of IB1/JIP1 Expression and JNK Signaling in Stroke.
Kim S · Experimental neurobiology · 2017
Animal study (in vivo) · rat · 7 results
- Neuroprotection of Exendin-4 by Enhanced Autophagy in a Parkinsonian Rat Model of α-Synucleinopathy.
Bu LL · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
Animal study (in vivo) · rat · 9 results
- Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy.
Rocha-Ferreira E · Brain : a journal of neurology · 2018
Animal study (in vivo) · mouse · 10 results
- Exendin-4 inhibits structural remodeling and improves Ca2+ homeostasis in rats with heart failure via the GLP-1 receptor through the eNOS/cGMP/PKG pathway.
Chen J · Peptides · 2017
Animal study (in vivo) · rat · 17 results
- Exendin-4 regulates lipid metabolism and fibroblast growth factor 21 in hepatic steatosis.
Lee J · Metabolism: clinical and experimental · 2014
Animal study (in vivo) · mouse · 5 results
- Exendin-4, a glucagon-like peptide-1 receptor agonist, attenuates neointimal hyperplasia after vascular injury.
Hirata Y · European journal of pharmacology · 2013
Animal study (in vivo) · c57bl and 6 mouse · 5 results
- Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogs.
Chae SY · Journal of controlled release : official journal of the Controlled Release Society · 2010
Animal study (in vivo) · 1 result
- Improvement of Transdermal Delivery of Exendin-4 Using Novel Tip-Loaded Microneedle Arrays Fabricated from Hyaluronic Acid.
Liu S · Molecular pharmaceutics · 2016
Animal study (in vivo) · rat · 3 results
- Exenatide reduces food intake and activates the enteric nervous system of the gastrointestinal tract and the dorsal vagal complex of the hindbrain in the rat by a GLP-1 receptor.
Washington MC · Brain research · 2010
Animal study (in vivo) · rat · 9 results
- Exendin-4 therapy in NOD mice with new-onset diabetes increases regulatory T cell frequency.
Xue S · Annals of the New York Academy of Sciences · 2008
Animal study (in vivo) · mouse · 3 results
- Exogenous peptide YY3-36 and Exendin-4 further decrease food intake, whereas octreotide increases food intake in rats after Roux-en-Y gastric bypass.
Fenske WK · International journal of obesity (2005) · 2012
Animal study (in vivo) · rat · 6 results
- Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats.
Simonsen L · American journal of physiology. Gastrointestinal and liver physiology · 2007
Animal study (in vivo) · rat · 13 results
- Combined Treatment with Exendin-4 and Metformin Attenuates Prostate Cancer Growth.
Tsutsumi Y · PloS one · 2015
Animal study (in vivo) · mouse · 12 results
- Long term exendin-4 treatment reduces food intake and body weight and alters expression of brain homeostatic and reward markers.
Yang Y · Endocrinology · 2014
Animal study (in vivo) · rat · 6 results
- Delivery of Exenatide and Insulin Using Mucoadhesive Intestinal Devices.
Gupta V · Annals of biomedical engineering · 2016
Animal study (in vivo) · 3 results
- Exenatide prevents fat-induced insulin resistance and raises adiponectin expression and plasma levels.
Li L · Diabetes, obesity & metabolism · 2008
Animal study (in vivo) · rat · 13 results
- Exenatide inhibits the growth of endometrial cancer Ishikawa xenografts in nude mice.
Zhang Y · Oncology reports · 2016
Animal study (in vivo) · mouse · 17 results