Exenatide (exendin-4) studies: 530 papers with results
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- Comparison of exendin-4 on beta-cell replication in mouse and human islet grafts.
Tian L · Transplant international : official journal of the European Society for Organ Transplantation · 2011
Animal study (in vivo) · mouse · 4 results
- Pharmacokinetic and pharmacodynamic modeling of exendin-4 in type 2 diabetic Goto-Kakizaki rats.
Gao W · The Journal of pharmacology and experimental therapeutics · 2011
Animal study (in vivo) · rat · 9 results
- Novel exenatide analogs with peptidic albumin binding domains: potent anti-diabetic agents with extended duration of action.
Levy OE · PloS one · 2014
Animal study (in vivo) · mouse · 3 results
- Exendin-4, a GLP-1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia-reperfusion injury.
Zhai R · British journal of pharmacology · 2020
Animal study (in vivo) · rat · 11 results
- The use of low molecular weight protamine to enhance oral absorption of exenatide.
Zhang L · International journal of pharmaceutics · 2018
Animal study (in vivo) · rat · 5 results
- Biological activity of AC3174, a peptide analog of exendin-4.
Hargrove DM · Regulatory peptides · 2007
Animal study (in vivo) · mouse · 3 results
- A vitamin B12 conjugate of exendin-4 improves glucose tolerance without associated nausea or hypophagia in rodents.
Mietlicki-Baase EG · Diabetes, obesity & metabolism · 2018
Animal study (in vivo) · rat · 5 results
- Exendin-4-encapsulated dissolving microneedle arrays for efficient treatment of type 2 diabetes.
Fakhraei Lahiji S · Scientific reports · 2018
Animal study (in vivo) · mouse · 2 results
- Exendin-4 promotes endothelial barrier enhancement via PKA- and Epac1-dependent Rac1 activation.
Li AQ · American journal of physiology. Cell physiology · 2015
Animal study (in vivo) · mouse · 11 results
- Hydrogel Drug Delivery System Using Self-Cleaving Covalent Linkers for Once-a-Week Administration of Exenatide.
Schneider EL · Bioconjugate chemistry · 2016
Animal study (in vivo) · rat · 4 results
- Tf ligand-receptor-mediated exenatide-Zn2+ complex oral-delivery system for penetration enhancement of exenatide.
Zhang L · Journal of drug targeting · 2018
Animal study (in vivo) · 5 results
- Exendin-4 Loaded Nanoparticles with a Lipid Shell and Aqueous Core Containing Micelles for Enhanced Intestinal Absorption.
Chen C · Journal of biomedical nanotechnology · 2015
Animal study (in vivo) · mouse · 6 results
- Exenatide ameliorates experimental non-alcoholic fatty liver in rats via suppression of toll-like receptor 4/NFκB signaling: Comparison to metformin.
Saad ZA · Life sciences · 2020
Animal study (in vivo) · rat · 1 result
- Effect of the GLP-1 analog exendin-4 and oxaliplatin on intrahepatic cholangiocarcinoma cell line and mouse model.
Chen BD · International journal of molecular sciences · 2013
Animal study (in vivo) · mouse · 9 results
- Chitosan-based thermosensitive hydrogel for nasal delivery of exenatide: Effect of magnesium chloride.
Li Y · International journal of pharmaceutics · 2018
Animal study (in vivo) · rat · 9 results
- The GLP-1 analogue exenatide improves hepatic and muscle insulin sensitivity in diabetic rats: tracer studies in the basal state and during hyperinsulinemic-euglycemic clamp.
Wu H · Journal of diabetes research · 2014
Animal study (in vivo) · sprague-dawley rats · 7 results
- Glycemic variability in newly diagnosed diabetic cats treated with the glucagon-like peptide-1 analogue exenatide extended release.
Krämer AL · Journal of veterinary internal medicine · 2020
Animal study (in vivo) · cat · 6 results
- Exendin-4 treatment expands graft beta-cell mass in diabetic mice transplanted with a marginal number of fresh islets.
Juang JH · Cell transplantation · 2008
Animal study (in vivo) · mouse · 9 results
- [D-Leu-4]-OB3, a synthetic peptide amide with leptin-like activity, augments the effects of orally delivered exenatide and pramlintide acetate on energy balance and glycemic control in insulin-resistant male C57BLK/6-m db/db mice.
Leinung MC · Regulatory peptides · 2012
Animal study (in vivo) · mouse · 20 results
- Oxyntomodulin analog and exendin-4 derivative lower plasma glucose in cattle.
ThanThan S · Domestic animal endocrinology · 2017
Animal study (in vivo) · cattle · 2 results
- Protective effects of GLP-1 analogues exendin-4 and GLP-1(9-36) amide against ischemia-reperfusion injury in rat heart.
Sonne DP · Regulatory peptides · 2008
Ex vivo tissue · rat · 5 results
- Effects of Exendin-4 on human adipose tissue inflammation and ECM remodelling.
Pastel E · Nutrition & diabetes · 2016
Ex vivo tissue · 8 results
- Exendin-4 enhances the sensitivity of prostate cancer to enzalutamide by targeting Akt activation.
Wenjing H · The Prostate · 2020
In vitro (cells) · 7 results
- Evaluation of an [(18)F]AlF-NOTA Analog of Exendin-4 for Imaging of GLP-1 Receptor in Insulinoma.
Kiesewetter DO · Theranostics · 2012
Not a test of Exenatide (exendin-4) alone · 12 results
- Combination therapy with pioglitazone/exenatide/metformin reduces the prevalence of hepatic fibrosis and steatosis: The efficacy and durability of initial combination therapy for type 2 diabetes (EDICT).
Lavynenko O · Diabetes, obesity & metabolism · 2022
Not a test of Exenatide (exendin-4) alone · 12 results
- Effective oral delivery of Exenatide-Zn2+ complex through distal ileum-targeted double layers nanocarriers modified with deoxycholic acid and glycocholic acid in diabetes therapy.
Han Y · Biomaterials · 2021
Not a test of Exenatide (exendin-4) alone · 12 results
- Dapagliflozin once-daily and exenatide once-weekly dual therapy: A 24-week randomized, placebo-controlled, phase II study examining effects on body weight and prediabetes in obese adults without diabetes.
Lundkvist P · Diabetes, obesity & metabolism · 2017
Not a test of Exenatide (exendin-4) alone · 10 results
- Gender-related different effects of a combined therapy of Exenatide and Metformin on overweight or obesity patients with type 2 diabetes mellitus.
Quan H · Journal of diabetes and its complications · 2016
Not a test of Exenatide (exendin-4) alone · 10 results
- Phase III Study on Efficacy and Safety of Triple Combination (Exenatide/Metformin/Biphasic Insulin Aspart) Therapy for Type 2 Diabetes Mellitus.
Su K · American journal of therapeutics · 2018
Not a test of Exenatide (exendin-4) alone · 10 results
- Intravitreal injection of exendin-4 analogue protects retinal cells in early diabetic rats.
Zhang Y · Investigative ophthalmology & visual science · 2011
Not a test of Exenatide (exendin-4) alone · 9 results
- Cost Effectiveness of Exenatide Once Weekly Versus Insulin Glargine and Liraglutide for the Treatment of Type 2 Diabetes Mellitus in Greece.
Tzanetakos C · Clinical drug investigation · 2018
Not a test of Exenatide (exendin-4) alone · 9 results
- Efficacy of Exenatide Administered Twice Daily in Body Mass Index Reduction in Patients with Type 2 Diabetes Mellitus.
Zhang J · International journal of clinical practice · 2022
Not a test of Exenatide (exendin-4) alone · 9 results
- Safety, efficacy and tolerability of exenatide in combination with insulin in the Association of British Clinical Diabetologists nationwide exenatide audit*.
Thong KY · Diabetes, obesity & metabolism · 2011
Not a test of Exenatide (exendin-4) alone · 8 results
- Dapagliflozin once daily plus exenatide once weekly in obese adults without diabetes: Sustained reductions in body weight, glycaemia and blood pressure over 1 year.
Lundkvist P · Diabetes, obesity & metabolism · 2017
Not a test of Exenatide (exendin-4) alone · 8 results
- Antiapoptotic actions of exendin-4 against hypoxia and cytokines are augmented by CREB.
Velmurugan K · Endocrinology · 2012
Not a test of Exenatide (exendin-4) alone · 8 results
- Target-mediated pharmacokinetic and pharmacodynamic model of exendin-4 in rats, monkeys, and humans.
Gao W · Drug metabolism and disposition: the biological fate of chemicals · 2012
Not a test of Exenatide (exendin-4) alone · 8 results
- Comparison of insulin lispro protamine suspension versus insulin glargine once daily added to oral antihyperglycaemic medications and exenatide in type 2 diabetes: a prospective randomized open-label trial.
Arakaki RF · Diabetes, obesity & metabolism · 2014
Not a test of Exenatide (exendin-4) alone · 8 results
- FGF21 contributes to metabolic improvements elicited by combination therapy with exenatide and pioglitazone in patients with type 2 diabetes.
Samms RJ · American journal of physiology. Endocrinology and metabolism · 2022
Not a test of Exenatide (exendin-4) alone · 8 results
- Effect of treatment with exenatide and pioglitazone or basal-bolus insulin on diabetic neuropathy: a substudy of the Qatar Study.
Ponirakis G · BMJ open diabetes research & care · 2020
Not a test of Exenatide (exendin-4) alone · 7 results
- Long-acting inhalable chitosan-coated poly(lactic-co-glycolic acid) nanoparticles containing hydrophobically modified exendin-4 for treating type 2 diabetes.
Lee C · International journal of nanomedicine · 2013
Not a test of Exenatide (exendin-4) alone · 7 results
- A randomized non-inferiority study comparing the addition of exenatide twice daily to sitagliptin or switching from sitagliptin to exenatide twice daily in patients with type 2 diabetes experiencing inadequate glycaemic control on metformin and sitagliptin.
Violante R · Diabetic medicine : a journal of the British Diabetic Association · 2012
Not a test of Exenatide (exendin-4) alone · 7 results
- Patient-reported outcomes among patients using exenatide twice daily or insulin in clinical practice in six European countries: the CHOICE prospective observational study.
Reaney M · Health and quality of life outcomes · 2013
Not a test of Exenatide (exendin-4) alone · 7 results
- EVALUATION OF INSULIN GLARGINE AND EXENATIDE ALONE AND IN COMBINATION: A RANDOMIZED CLINICAL TRIAL WITH CONTINUOUS GLUCOSE MONITORING AND AMBULATORY GLUCOSE PROFILE ANALYSIS.
Carlson AL · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2019
Not a test of Exenatide (exendin-4) alone · 7 results
- Exenatide Twice Daily Plus Glargine Versus Aspart 70/30 Twice Daily in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Premixed Human Insulin and Metformin.
Chen X · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2021
Not a test of Exenatide (exendin-4) alone · 7 results
- Effects of exenatide alone and in combination with daclizumab on beta-cell function in long-standing type 1 diabetes.
Rother KI · Diabetes care · 2009
Not a test of Exenatide (exendin-4) alone · 6 results
- Effects of exenatide and open-label SGLT2 inhibitor treatment, given in parallel or sequentially, on mortality and cardiovascular and renal outcomes in type 2 diabetes: insights from the EXSCEL trial.
Clegg LE · Cardiovascular diabetology · 2019
Not a test of Exenatide (exendin-4) alone · 6 results
- Evaluation of exenatide vs. insulin glargine in type 2 diabetes: cost-effectiveness analysis in the German setting.
Mittendorf T · Diabetes, obesity & metabolism · 2009
Not a test of Exenatide (exendin-4) alone · 6 results
- Exenatide versus insulin glargine: a cost-effectiveness evaluation in patients with Type 2 diabetes in Switzerland.
Brändle M · International journal of clinical pharmacology and therapeutics · 2009
Not a test of Exenatide (exendin-4) alone · 6 results
- The metabolic effects of adding exenatide to basal insulin therapy when targeting remission in early type 2 diabetes in a randomized clinical trial.
Retnakaran R · Nature communications · 2022
Not a test of Exenatide (exendin-4) alone · 6 results
- Effects of HbA1c and weight reduction on blood pressure in patients with type 2 diabetes mellitus treated with exenatide*.
Paul S · Diabetes, obesity & metabolism · 2012
Not a test of Exenatide (exendin-4) alone · 6 results