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Study · Animal study (in vivo) · mouse · 2010

1 result

The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics.

Chae SY, Choi YG, Son S, Jung SY, Lee DS, Lee KC

Journal of controlled release : official journal of the Controlled Release Society20 Jan 2010Cited by 59 (Europe PMC)

PMID20093159 (opens in a new tab)DOI10.1016/j.jconrel.2010.01.024 (opens in a new tab)PepBankPUB-20093159
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In type 2 diabetic mice, a single exendin‑4 injection induced normoglycemia for 6 hours.

    In plain wordsIn mice with diabetes, one exendin‑4 injection produced normal blood glucose for 6 hours.

    Peptide
    Exenatide (exendin-4)
    Outcome
    Not applicableDuration of normoglycemia
    Study

    mousen: not reported in source

    type 2 diabetic mice
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    20nmol/mouse · injectionAs given in this study (mouse).

    Measurements

    Normoglycemia duration
    6 h
    exendin-4

    Source sentences

    Summary
    The protracted antidiabetic effects of LUA-M1 were also confirmed by prolonged normoglycemia observed in type 2 diabetic mice (20nmol/mouse single injection of exendin-4 or LUA-M1 induced normoglycemia for 6 or 24h, respectively).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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