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Study · Animal study (in vivo) · 2010

1 result

Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogs.

Chae SY, Jin CH, Shin JH, Son S, Kim TH, Lee S, Youn YS, Byun Y, Lee MS, Lee KC

Journal of controlled release : official journal of the Controlled Release Society10 Nov 2009Cited by 47 (Europe PMC)

PMID19900495 (opens in a new tab)DOI10.1016/j.jconrel.2009.10.025 (opens in a new tab)PepBankPUB-19900495
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Pharmacokinetics

    In the pharmacokinetic comparison, native exendin‑4 had an elimination half-life of 1.6 hours.

    In plain wordsIn animals, native exendin‑4 had an elimination half-life of 1.6 hours.

    Peptide
    Exenatide (exendin-4)
    Outcome
    Not applicableElimination half-life
    Study

    n: not reported in source

    Outcome group
    Pharmacokinetics · Pharmacology
    Studied dose
    Dose not stated

    Measurements

    Elimination half-life
    1.6 h
    native exendin-4

    Source sentences

    Summary
    Furthermore, the pharmacokinetic characteristics were dramatically enhanced, that is, absorption was delayed and elimination half-life was increased (1.6+/-0.4 and 9.7+/-1.4h by exendin-4 and LCA-M1, respectively).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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