MIF-1 (Pro-Leu-Gly-NH2) studies: 89 papers with results
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- Prolyl-leucyl-glycinamide shares some effects with oxytocin but decreases oxytocin levels.
Petersson M · Physiology & behavior · 2004
Animal study (in vivo) · rat · 8 results
- Antiamnesic effects of D-pipecolic acid and analogues of Pro-Leu-Gly-NH2 in rats.
Kovács GL · Pharmacology, biochemistry, and behavior · 1988
Animal study (in vivo) · rat · 2 results
- Effect of prolyl-leucyl-glycinamide on blood pressure, heart rate and angiotensin converting enzyme activity in spontaneously hypertensive and Wistar-Kyoto normotensive rats.
Das S · General pharmacology · 1985
Animal study (in vivo) · rat · 10 results
- Effect of chronic treatment with morphine on the binding of 3H-N-n-propylnorapomorphine to striatal membranes of rats: influence of prolyl-leucyl-glycinamide.
Das S · Pharmacology · 1985
Animal study (in vivo) · rat · 3 results
- MIF-1: effects on norepinephrine, dopamine and serotonin metabolism in certain discrete brain regions.
Singhal RL · Pharmacology, biochemistry, and behavior · 1982
Animal study (in vivo) · rat · 21 results
- PLG regulates hnRNP-L expression in the rat striatum and pre-frontal cortex: identification by ddPCR.
Costain WJ · Peptides · 2003
Animal study (in vivo) · rat · 5 results
- Prolyl-leucyl-glycinamide, thyrotropin-releasing hormone and beta-endorphin-(10-16), like antidepressants, antagonize melatonin-induced behavioural changes in rats.
Hatta K · European journal of pharmacology · 1995
Animal study (in vivo) · rat · 1 result
- MIF-1 fails to modify agonist-induced oral activity in neonatal 6-OHDA-treated rats.
Gong L · Peptides · 1993
Animal study (in vivo) · rat · 4 results
- The effects of MIF-I, beta-endorphin and alpha-MSH on d-amphetamine induced paradoxical behavioral thermoregulation: possible involvement of the dopaminergic system.
Yehuda S · Peptides · 1985
Animal study (in vivo) · rat · 2 results
- Dose-related effect of the oxytocin fragment (prolyl-leucyl-glycinamide) on ?-MPT-induced catecholamine disappearance and serotonin level in rat brain.
Szabó G · Neurochemistry international · 1981
Animal study (in vivo) · rat · 8 results
- Effects of the oxytocin fragment prolyl-leucyl-glycinamide on sexual behavior in the rat.
Gorzalka BB · Pharmacology, biochemistry, and behavior · 1991
Animal study (in vivo) · rat · 5 results
- Attenuation of SCH 23390-induced alteration of striatal dopamine D1 receptor ontogeny by prolyl-leucyl-glycinamide in the rat.
Kostrzewa RM · Neuropharmacology · 1989
Animal study (in vivo) · rat · 5 results
- Neuropeptides related to neurohypophyseal hormones interfere with apomorphine-induced behavioral changes.
Xiao XS · Neuropeptides · 1984
Animal study (in vivo) · rat · 7 results
- Intensification and attenuation of morphine dependence by D-aspartic acid and PLG.
Koyuncuoğlu H · Pharmacology, biochemistry, and behavior · 1990
Animal study (in vivo) · mouse and rat · 3 results
- Prolyl-leucyl-glycinamide (PLG): inhibition of offensive aggression in mice.
Kavaliers M · Life sciences · 1986
Animal study (in vivo) · mouse · 4 results
- Hypothalamic peptide hormone, prolyl-leucyl-glycinamide and analog, inhibit tolerance to the analgesic and locomotor depressant but not to the locomotor stimulant effects of morphine in the mouse.
Bhargava HN · Neuropharmacology · 1982
Animal study (in vivo) · mouse · 3 results
- Effects of dopaminergic and cholinergic drugs. naloxone and l-prolyl-leucyl-glycinamide on LSD-induced catalepsy.
Chiu S · Naunyn-Schmiedeberg's archives of pharmacology · 1980
Animal study (in vivo) · rat · 1 result
- Effects of prolyl-leucyl-glycinamide and cyclo(leucyl-glycine) on morphine-induced antinociception and brain mu, delta and kappa opiate receptors.
Bhargava HN · Life sciences · 1983
Animal study (in vivo) · mouse · 4 results
- Effects of neurohypophyseal hormones on food-reinforced classical conditioning in the rat.
Ibragimov RS · Acta physiologica Hungarica · 1988
Animal study (in vivo) · rat · 4 results
- Comparative effects of prolyl-leucyl-glycinamide and naloxone on morphine-induced inhibition of gastrointestinal transit.
Pillai NP · Pharmacology, biochemistry, and behavior · 1984
Animal study (in vivo) · mouse · 4 results
- Central action of melanostatin (MIF-1) in mice.
Brus R · Acta physiologica Polonica · 1984
Animal study (in vivo) · mouse · 5 results
- The action of prolyl-leucyl-glycinamide (PLG) on the nigrostriatal pathway of the rat.
Pereira JS · Arquivos de neuro-psiquiatria · 1990
Animal study (in vivo) · rat · 3 results
- [The effect of prolyl-leucyl-glycine (MIF-1) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on dopamine levels of the striatum].
Sheng JG · Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry · 1989
Animal study (in vivo) · mouse · 2 results
- Effect on brain monoamines in the rat of substituted and protected analogues of the oxytocin fragment, prolyl-leucyl-glycinamide following N-terminal substitution by homoproline.
Szabó G · Acta physiologica Hungarica · 1983
Animal study (in vivo) · rat · 3 results
- Neurohypophysial peptides and the hippocampus. II. Excitation of rat hippocampal neurones by oxytocin and vasopressin applied in vitro.
Tiberiis BE · Neuropeptides · 1983
Ex vivo tissue · rat · 10 results
- Control of bioactive corticotropin release from the neuro-intermediate lobe of the rat pituitary in vitro.
Fischer JL · Endocrinology · 1977
Ex vivo tissue · rat · 2 results
- alpha-MSH and Pro-Leu-Gly-NH2 (PLG; MIF-1): influence on dopamine (DA) uptake in crude synaptosomal preparations from rat mediobasal hypothalamus (MBH) and caudate putamen (CP).
Torre E · Peptides · 1984
Ex vivo tissue · rat · 2 results
- Modulation of agonist stimulated adenylyl cyclase and GTPase activity by L-pro-L-leu-glycinamide and its peptidomimetic analogue in rat striatal membranes.
Mishra RK · Neuroscience letters · 1999
Ex vivo tissue · rat · 2 results
- Inhibition by L-prolyl-L-leucyl-glycinamide (PLG) of alpha-melanocyte stimulating hormone release from hypothalamic slices.
Scimonelli T · Peptides · 1982
Ex vivo tissue · rat · 4 results
- Effects of melanostatine (MIF-1) on focal potentials in slices of rat brain cortex.
Mokrushin AA · Neuropeptides · 1991
Ex vivo tissue · rat · 6 results
- PLGamide characterization and role in osmoregulation in leech brain.
Salzet M · Brain research. Molecular brain research · 2000
Ex vivo tissue · leech · 7 results
- Synthesis, Pharmacological, and Biological Evaluation of MIF-1 Picolinoyl Peptidomimetics as Positive Allosteric Modulators of D2R.
Sampaio-Dias IE · ACS chemical neuroscience · 2019
In vitro (cells) · 4 results
- Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D2 Receptors.
Silva-Reis SC · ACS medicinal chemistry letters · 2023
In vitro (cells) · 2 results
- Proline Homologation in Melanostatin Neuropeptide: Discovery of Potent Modulators of the Dopamine D2 Receptors.
Sampaio-Dias IE · ACS medicinal chemistry letters · 2025
In vitro (cells) · 1 result
- Discovery of bridged melanostatin derivatives as potent allosteric modulators of the dopamine D2 receptors with improved permeability.
Sampaio-Dias IE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026
In vitro (cells) · 2 results
- Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML).
Sampaio-Dias IE · ACS chemical neuroscience · 2021
In vitro (cell-free) · 1 result
- Differences in prolyl-leucyl-glycinamide metabolism by hypothalamus, pituitary and cerebral cortex of male and female rats.
Celis ME · Neurochemistry international · 1982
In vitro (cell-free) · rat · 9 results
- Evaluation of Density Functionals, SCC-DFTB, Neglect of Diatomic Differential Overlap (NDDO) Models and Molecular Mechanics Methods for Prolyl-Leucyl-Glycinamide (PLG) and Structural Derivatives.
Wood RL · Theochem · 2010
Not a test of MIF-1 (Pro-Leu-Gly-NH2) alone · 2 results
- Possible association of increased rat behavioral effects and increased striatal dopamine and norepinephrine levels during the DOPA-potentiation test.
Spirtes MA · Pharmacology, biochemistry, and behavior · 1976
Not a test of MIF-1 (Pro-Leu-Gly-NH2) alone · 1 result