alpha-MSH and Pro-Leu-Gly-NH2 (PLG; MIF-1): influence on dopamine (DA) uptake in crude synaptosomal preparations from rat mediobasal hypothalamus (MBH) and caudate putamen (CP).

Torre E, Celis ME, Chiocchio SR

Peptides1 Jul 1984Cited by 20 (Europe PMC)

PMID6149522DOI10.1016/0196-9781(84)90004-4PepBankPUB-06149522

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

01LabEx vivo tissueActivity measurement
In rat caudate putamen synaptosomal preparations, PLG did not significantly affect tritiated dopamine uptake.
In plain wordsIn lab tests, PLG did not change dopamine uptake in rat caudate putamen preparations compared with control.
Peptide
MIF-1 (Pro-Leu-Gly-NH2)
Outcome
No significant changeCaudate putamen dopamine uptake
Study
ratn: not reported in source
Rat brain synaptosomal fractions
Comparator
Control
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
Dose not stated
Source sentences
Summary
PLG did not have any significant effect on [3H]DA uptake either in the CP or in the MBH.
1 context sentence(design, population, supporting numbers)
Summary · context
The uptake of tritiated dopamine [3H] (DMI insensitive DA uptake) by synaptosomal fractions isolated from rat mediobasal hypothalamus (MBH) and caudate putamen (CP) was measured in the presence of different concentrations of alpha-melanocyte stimulating hormone (alpha-MSH) and Pro-Leu-Gly-NH2 (PLG;…
Report a problemFND-0614952201
02LabEx vivo tissueActivity measurement
In rat mediobasal hypothalamic synaptosomal preparations, PLG did not significantly affect tritiated dopamine uptake.
In plain wordsIn lab tests, PLG did not change dopamine uptake in rat hypothalamic preparations compared with control.
Peptide
MIF-1 (Pro-Leu-Gly-NH2)
Outcome
No significant changeMediobasal hypothalamus dopamine uptake
Study
ratn: not reported in source
Rat brain synaptosomal fractions
Comparator
Control
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
Dose not stated
Source sentences
Summary
PLG did not have any significant effect on [3H]DA uptake either in the CP or in the MBH.
1 context sentence(design, population, supporting numbers)
Summary · context
The uptake of tritiated dopamine [3H] (DMI insensitive DA uptake) by synaptosomal fractions isolated from rat mediobasal hypothalamus (MBH) and caudate putamen (CP) was measured in the presence of different concentrations of alpha-melanocyte stimulating hormone (alpha-MSH) and Pro-Leu-Gly-NH2 (PLG;…
Report a problemFND-0614952202

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
22 Oct 2026, 02:26 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC

Subjects

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