Skip to content

Study · Animal study (in vivo) · rat · 1988

4 results

Effects of neurohypophyseal hormones on food-reinforced classical conditioning in the rat.

Ibragimov RS, Kádár T, Telegdy G

Acta physiologica Hungarica1 Jan 1988Cited by 1 (Europe PMC)

PMID2898868 (opens in a new tab)PepBankPUB-02898868
Publisher pageAsk about this study
Jump to 4 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, oxytocin did not significantly affect food-reinforced conditioning, although performance tended to increase.

    In plain wordsIn rats, oxytocin did not significantly change food-reinforced conditioning, although performance tended to increase.

    Peptide
    Oxytocin
    Outcome
    No significant changeFood-reinforced conditioning
    Study

    ratn: not reported in source

    food-reinforced classical conditioning
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    150, 300 and 600 mU/kg · intraperitoneal · six daysAs given in this study (rat).

    Source sentences

    Summary
    These same mU doses of OXT did not significantly affect the food-reinforced conditioning, although a consequent tendency towards increased performance (the opposite action to vasopressin) was observed.
    2 context sentences
    Summary · context
    The highest (600 mU/kg) dose of LVP inhibited acquisition, and all LVP doses tested (150, 300 and 600 mU/kg) facilitated the extinction of conditioned behaviour.
    Summary · context
    The effects of different doses of lysine vasopressin (LVP) and oxytocin (OXT) were studied on the six-day acquisition or extinction of a food-reinforced classical conditioning reflex (conditional stimulus: light) when intraperitoneal (ip.) injections were carried out 20 min prior to the behavioural sessions.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, oxytocin significantly facilitated extinction of food-reinforced conditioning.

    In plain wordsIn rats, oxytocin increased extinction of a learned food response.

    Peptide
    Oxytocin
    Outcome
    IncreaseExtinction of food-reinforced conditioning
    Study

    ratn: not reported in source

    food-reinforced classical conditioning
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    1200 mU/kg · intraperitoneal · six daysAs given in this study (rat).

    Source sentences

    Summary
    When 2.5 or 25 micrograms/kg doses of desglycinamide-arginine-vasopressin (DGAVP), a 500 micrograms/kg dose of prolyl-leucyl-glycinamide (PLG) or a 1200 mU/kg dose of OXT was injected during the extinction sessions, 2.5 micrograms/kg DGAVP and 1200 mU/kg OXT significantly facilitated extinction; the…
    1 context sentence
    Summary · context
    The effects of different doses of lysine vasopressin (LVP) and oxytocin (OXT) were studied on the six-day acquisition or extinction of a food-reinforced classical conditioning reflex (conditional stimulus: light) when intraperitoneal (ip.) injections were carried out 20 min prior to the behavioural sessions.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats, PLG did not affect extinction of food-reinforced conditioning.

    In plain wordsIn rats, PLG did not affect extinction of a learned food response.

    Peptide
    MIF-1 (Pro-Leu-Gly-NH2)
    Outcome
    No significant changeExtinction of food-reinforced conditioning
    Study

    ratn: not reported in source

    food-reinforced classical conditioning
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    500 micrograms/kg · intraperitoneal · six daysAs given in this study (rat).

    Source sentences

    Summary
    When 2.5 or 25 micrograms/kg doses of desglycinamide-arginine-vasopressin (DGAVP), a 500 micrograms/kg dose of prolyl-leucyl-glycinamide (PLG) or a 1200 mU/kg dose of OXT was injected during the extinction sessions, 2.5 micrograms/kg DGAVP and 1200 mU/kg OXT significantly facilitated extinction; the…
    1 context sentence
    Summary · context
    The effects of different doses of lysine vasopressin (LVP) and oxytocin (OXT) were studied on the six-day acquisition or extinction of a food-reinforced classical conditioning reflex (conditional stimulus: light) when intraperitoneal (ip.) injections were carried out 20 min prior to the behavioural sessions.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In food-deprived rats, oxytocin did not influence food intake in a nonconditional situation.

    In plain wordsIn food-deprived rats, oxytocin did not change food intake outside conditioning.

    Peptide
    Oxytocin
    Outcome
    No significant changeFood intake in a nonconditional situation
    Study

    ratn: not reported in source

    22 h food-deprived rats
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    300, 600 or 1200 mU/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    LVP in a dose of 300 or 600 mU/kg and OXT in a dose of 300, 600 or 1200 mU/kg did not influence the food intake of 22 h food-deprived rats in a nonconditional situation.
    1 context sentence
    Summary · context
    The effects of different doses of lysine vasopressin (LVP) and oxytocin (OXT) were studied on the six-day acquisition or extinction of a food-reinforced classical conditioning reflex (conditional stimulus: light) when intraperitoneal (ip.) injections were carried out 20 min prior to the behavioural sessions.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 18:59 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:54 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.