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Study · Ex vivo tissue · rat · 1977

2 results

Control of bioactive corticotropin release from the neuro-intermediate lobe of the rat pituitary in vitro.

Fischer JL, Moriarty CM

Endocrinology1 Apr 1977Cited by 31 (Europe PMC)

PMID189989 (opens in a new tab)DOI10.1210/endo-100-4-1047 (opens in a new tab)PepBankPUB-00189989
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In isolated rat pituitary tissue, PLG had no effect on basal release of biologically active ACTH.

    In plain wordsIn lab tests on rat pituitary tissue, PLG did not change basal release of active ACTH.

    Peptide
    MIF-1 (Pro-Leu-Gly-NH2)
    Outcome
    No significant changeBasal ACTH release
    Study

    ratn: not reported in source

    isolated neuro-intermediate pituitary lobe
    Outcome group
    Endogenous peptide levels · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Similarly, the tripeptide, prolyl-leucyl-glycinamide, which has been reported by some to inhibit MSH release, had no effect on either the basal or stimulated release of ACTH.
    1 context sentence
    Summary · context
    The purpose of this study was to identify agents capable of regulating the release of biologically active ACTH from the isolated neuro-intermediate lobe of the rat pituitary.
  2. 02LabEx vivo tissueActivity measurement

    In isolated rat pituitary tissue, PLG had no effect on stimulated release of biologically active ACTH.

    In plain wordsIn lab tests on rat pituitary tissue, PLG did not change stimulated release of active ACTH.

    Peptide
    MIF-1 (Pro-Leu-Gly-NH2)
    Outcome
    No significant changeStimulated ACTH release
    Study

    ratn: not reported in source

    isolated neuro-intermediate pituitary lobe
    Outcome group
    Endogenous peptide levels · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Similarly, the tripeptide, prolyl-leucyl-glycinamide, which has been reported by some to inhibit MSH release, had no effect on either the basal or stimulated release of ACTH.
    1 context sentence
    Summary · context
    The purpose of this study was to identify agents capable of regulating the release of biologically active ACTH from the isolated neuro-intermediate lobe of the rat pituitary.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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