Skip to content

Study · Animal study (in vivo) · rat · 1983

3 results

Effect on brain monoamines in the rat of substituted and protected analogues of the oxytocin fragment, prolyl-leucyl-glycinamide following N-terminal substitution by homoproline.

Szabó G, Kovács GL, Baláspiri L, Telegdy G

Acta physiologica Hungarica1 Jan 1983

PMID6139932 (opens in a new tab)PepBankPUB-06139932
Publisher pageAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats, native PLG increased striatal serotonin content.

    In plain wordsIn rats, native PLG increased serotonin in the striatum.

    Peptide
    MIF-1 (Pro-Leu-Gly-NH2)
    Outcome
    IncreaseStriatal serotonin content
    Study

    ratn: not reported in source

    Brain monoamine measurements
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The parent molecule (PLG) increased the 5-HT content in the striatum and the NA and DA levels in the dorsal hippocampus.
    1 context sentence
    Title · context
    Effect on brain monoamines in the rat of substituted and protected analogues of the oxytocin fragment, prolyl-leucyl-glycinamide following N-terminal substitution by homoproline.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats, native PLG increased dorsal hippocampal noradrenaline levels.

    In plain wordsIn rats, native PLG increased noradrenaline in the dorsal hippocampus.

    Peptide
    MIF-1 (Pro-Leu-Gly-NH2)
    Outcome
    IncreaseDorsal hippocampal noradrenaline
    Study

    ratn: not reported in source

    Brain monoamine measurements
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The parent molecule (PLG) increased the 5-HT content in the striatum and the NA and DA levels in the dorsal hippocampus.
    1 context sentence
    Title · context
    Effect on brain monoamines in the rat of substituted and protected analogues of the oxytocin fragment, prolyl-leucyl-glycinamide following N-terminal substitution by homoproline.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rats, native PLG increased dorsal hippocampal dopamine levels.

    In plain wordsIn rats, native PLG increased dopamine in the dorsal hippocampus.

    Peptide
    MIF-1 (Pro-Leu-Gly-NH2)
    Outcome
    IncreaseDorsal hippocampal dopamine
    Study

    ratn: not reported in source

    Brain monoamine measurements
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The parent molecule (PLG) increased the 5-HT content in the striatum and the NA and DA levels in the dorsal hippocampus.
    1 context sentence
    Title · context
    Effect on brain monoamines in the rat of substituted and protected analogues of the oxytocin fragment, prolyl-leucyl-glycinamide following N-terminal substitution by homoproline.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 18:59 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:54 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.